| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Lactobacillus plantarum possess tRNAIle(UAU)-like molecules. As the first aim, the RNA was analyzed to clarify its use for translation. The RNA binds to AUA codon on the ribosome. However its binding with translation factor EF-Tu has not been confirmed. In order to investigate the extra translational function of tRNAIle (UAU)-like molecule, some affinity proteins of the RNA were identified. In addition, a deletion mutant of both two tRNAIle(UAU) genes is considered to be lethal since the double deletion mutant has not been obtained.
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