| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Outline of Final Research Achievements |
In this study we researched relationship between diffraction resolution of protein crystals and high pressure. For several kinds of proteins, diffraction data of crystals were collected and analyzed. High pressure tended to improve diffraction resolution of proteins which have low molecular weight. The reason is considered that high pressure makes hydration structure ordered and as a result diffraction ability of entire crystal improve. High pressure could improve crystal resolution of proteins which have low molecular weight, regardless of kinds of proteins or crystallization conditions.
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