| Project/Area Number |
16K18582
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Tohoku University |
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Principal Investigator |
Kohatsu Soh 東北大学, 生命科学研究科, 助教 (40571930)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ショウジョウバエ / 視覚行動 / 求愛行動 / 神経行動学 / 本能行動 / 視覚 / fruitless / 光遺伝学 / カルシウムイメージング / 神経科学 / 脳・神経 / 昆虫 |
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| Outline of Final Research Achievements |
In this study, we found that two subsets of interneurons that express a sex determination gene fruitless are involved in vision-dependent courtship regulation in male Drosophila. Optogenetically activating either of these neurons, Lv1 + Ld neurons or AL5a neurons, induced locomotion turn, which is the part female chasing that a male show during courtship. In vivo Ca2+ imaging demonstrated that these neurons show Ca2+ rise during presentation of visual stimulus that can induce locomotion turn. GRASP analysis suggested that these two subsets of interneurons have synaptic contact in a brain region optic tubercle. Collectively, these neurons are suggested to consist visual circuits that mediate behavior regulation during courtship.
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