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Mathematical modeling of sex change in coral fishes: integration of the sex controlling gene expression and the evolutionary responses to social status

Research Project

Project/Area Number 16K18624
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ecology/Environment
Research InstitutionNara Women's University (2018-2019)
Kanagawa University (2016-2017)

Principal Investigator

YAMAGUCHI Sachi  奈良女子大学, 大和・紀伊半島学研究所, 協力研究員 (20709191)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsホルモンダイナミックス / アロマターゼ / 双方向性転換 / 社会的地位 / 遺伝子発現 / 温度性決定 / 雌雄同体 / 自家受精 / 性システム / 性転換 / 分業 / 進化生態 / 数理モデル
Outline of Final Research Achievements

In order to establish a new approach that bridges between physiology/molecular biology and ecology/behavioral biology, I focused on “sexual” phenomena, such as sex change in fish and temperature sex determination in fish and reptiles. I start with mathematical models of gene expression and physiological mechanism and examined the evolutionary processes acting on the system. I made progresses on the following four points: [1] time asymmetry in bidirectional sex change brought by hormone-enzyme kinetics; [2] the advantage of bisexual gonad in bidirectional sex changers; [3] why is bidirectional change rare? and [4] modeling the physiological mechanism of temperature-dependent sex determination. Focusing on "adaptability", I analyzed [1] coexistence conditions of selfing hermaphrodites and males, and [2] task allocation in eusocial ants.

Academic Significance and Societal Importance of the Research Achievements

生物適応戦略モデルは、生物個体が残す子どもの数が最も多い生き方が広まり集団が置き換わる、という進化プロセスに注目し、適応度最大化問題に帰着させて大きな成功を収めてきた。他方、近年の分子生物学の目覚ましい発展により、環境や社会相互作用への応答、つまり表現型可塑性の分子生物学的基盤が明らかになりつつある。本研究では、表現型をもたらす生理学的機構をモデルに取り入れ、遺伝子発現や遺伝子制御ネットワークを考慮した新しい進化生物学モデルの展開を行った。このアプローチは、分子生物学や生理学の実験研究と動物行動学や生態学の研究を、数理生物学によってつなぐ、全く新しい共同研究の在り方を推進するものである。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (25 results)

All 2020 2019 2018 2017 2016

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 2 results,  Acknowledgement Compliant: 3 results) Presentation (17 results) (of which Invited: 1 results) Book (2 results)

  • [Journal Article] Task allocation in a cooperative society: specialized castes or age-dependent switching among ant workers2020

    • Author(s)
      Yoh Iwasa, Sachi Yamaguchi
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1

    • DOI

      10.1038/s41598-020-59920-5

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Why is bidirectional sex change rare?2018

    • Author(s)
      Sachi Yamaguchi, Yoh Iwasa
    • Journal Title

      Journal of Theoretical Biology

      Volume: 453 Pages: 136-145

    • DOI

      10.1016/j.jtbi.2018.05.024

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Temperature-dependent sex determination, realized by hormonal dynamics with enzymatic reactions sensitive to ambient temperature2018

    • Author(s)
      Sachi Yamaguchi, Yoh Iwasa
    • Journal Title

      Journal of Theoretical Biology

      Volume: 453 Pages: 146-155

    • DOI

      10.1016/j.jtbi.2018.05.023

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Advantage for the sex changer who retains the gonad of the nonfunctional sex2017

    • Author(s)
      Sachi Yamaguchi, Yoh Iwasa
    • Journal Title

      Behavioral Ecology and Sociobiology

      Volume: 71 Issue: 2 Pages: 39-39

    • DOI

      10.1007/s00265-017-2269-5

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Be a good loser: a theoretical model for subordinate decision-making on bi-directional sex change in haremic fishes2017

    • Author(s)
      Kota Sawada, Sachi Yamaguchi, Yoh Iwasa
    • Journal Title

      Journal of Theoretical Biology

      Volume: 421 Pages: 127-135

    • DOI

      10.1016/j.jtbi.2017.03.029

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Time required for sex change in teleost fishes: hormonal dynamics shaped by selection2016

    • Author(s)
      Sachi Yamaguchi
    • Journal Title

      Journal of Theoretical Biology

      Volume: 407 Pages: 339-348

    • DOI

      10.1016/j.jtbi.2016.07.012

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 性比と他殖/自殖性の共進化:マングローブ・キリフィッシュを例に2020

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      第67回日本生態学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 性比と他殖/自殖性の共進化:マングローブ・キリフィッシュを例に2020

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      ゲーム理論ワークショップ2020
    • Related Report
      2019 Annual Research Report
  • [Presentation] 来るべき性転換のチャンスに備える魚2019

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      2019年度(第29回)日本数理生物学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 性比と他殖/自殖性の共進化:マングローブ・キリフィッシュを例に2019

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      第38回動物行動学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] なぜ双方向性転換は稀なのかーアロマターゼ遺伝子発現ダイナミックスによる説明2019

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      第42回日本分子生物学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 爬虫類は卵の孵化温度で性が決まる:適応性と分子機構2019

    • Author(s)
      山口幸
    • Organizer
      ゲーム理論ワークショップ2019
    • Related Report
      2018 Research-status Report
  • [Presentation] 温度性決定をもたらす生理機構の数理的研究:アレニウス則が語ること2019

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      日本生態学会第66回大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 温度性決定をもたらす生理機構について2018

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      日本動物行動学会 第37回大会
    • Related Report
      2018 Research-status Report
  • [Presentation] なぜ双方向性転換は稀なのかーホルモンのダイナミックスによる説明2018

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      第34回 個体群生態学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 生物の性の多様性を数理モデルで理解する2018

    • Author(s)
      山口幸
    • Organizer
      数理工学ワークショップ マルチエージェントシステムの数理とシミュレーション
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 性転換するサンゴ礁の魚は、両性の生殖巣を持つべきか?2017

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      日本生態学会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2017-03-16
    • Related Report
      2016 Research-status Report
  • [Presentation] 性転換するサンゴ礁の魚は、両性の生殖巣を持つべきか?2017

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      ゲーム理論ワークショップ2017
    • Place of Presentation
      電気通信大学
    • Year and Date
      2017-03-05
    • Related Report
      2016 Research-status Report
  • [Presentation] 性転換するサンゴ礁の魚は、両性の生殖腺を持つべきか?2017

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      日本動物行動学会
    • Related Report
      2017 Research-status Report
  • [Presentation] なぜ双方向性転換は稀なのかーホルモンダイナミックスによる説明2017

    • Author(s)
      山口幸、巌佐庸
    • Organizer
      日本数理生物学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 温度性決定をもたらす生理機構について2017

    • Author(s)
      巌佐庸、山口幸
    • Organizer
      日本数理生物学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Advantage for the sex changer who retains the gonad of the nonfunctional sex2017

    • Author(s)
      Sachi Yamaguchi, Yoh Iwasa
    • Organizer
      個体群生態学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Time required for sex change in teleost fishes: hormonal dynamics shaped by selection2016

    • Author(s)
      Sachi Yamaguchi
    • Organizer
      日本数理生物学会
    • Place of Presentation
      九州大学
    • Year and Date
      2016-09-09
    • Related Report
      2016 Research-status Report
  • [Book] An evolutionary ecological approach to sex allocation and sex determination in crustaceans. In Cothran R, Thiel M (eds) "The Natural History of the Crustacea: Reproductive Biology: Volume VI." pp. 177-196.2020

    • Author(s)
      Kota Sawada, Sachi Yamaguchi
    • Total Pages
      568
    • Publisher
      Oxford University Press
    • ISBN
      9780190688554
    • Related Report
      2019 Annual Research Report
  • [Book] Life history constraints facilitate the evolution of androdioecy and male dwarfing. In Leonard JL (ed) "Transitions between sexual systems: understanding the mechanisms of, and pathways between, dioecy, hermaphroditism and other sexual systems." pp. 247-267.2019

    • Author(s)
      Sachi Yamaguchi
    • Total Pages
      363
    • Publisher
      Springer
    • ISBN
      9783319941394
    • Related Report
      2019 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2021-02-19  

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