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Investigation of plant breeding for Ephedra species

Research Project

Project/Area Number 16K18894
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Natural medicines
Research InstitutionKanazawa University

Principal Investigator

ANDO Hirokazu  金沢大学, 薬学系, 助教 (00768731)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsマオウ / 育種 / エフェドリン / 栽培
Outline of Final Research Achievements

This research aims to grow a new breed and to develop a quality evaluation method of Ephedra species which is required to cultivate domestic. In plant breeding, we successfully produce two types through breed E. sinica and E. likiangensis; one contains high total alkaloids, the other does not contain them. This is a first attempt to breed Ephedra species and it suggests a possible way to control the amount of components. In addition we revealed a correlation between total alkaloids and total tannin contents which is useful to evaluate a quality of Ephedra species not including alkaloids.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (11 results)

All 2018 2017 2016 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (6 results) Remarks (1 results)

  • [Journal Article] The Botanical Origin of Ephedra Herb used in Xinjiang Uyghur Autonomous Region of China2018

    • Author(s)
      Si-ran Ni, Mutalifu Nilufaer, Hirokazu Ando, Yohei Sasaki, Masayuki Mikage
    • Journal Title

      The Japanese Journal of Medicinal Resources

      Volume: 39(2) Pages: 37-43

    • NAID

      40022285481

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マオウ属植物の栽培研究(第9報)マオウ属植物 Ep-13 草質茎のアルカロイド含量の局在性について2016

    • Author(s)
      安藤広和、草場大作、御影雅幸、佐々木陽平
    • Journal Title

      薬用植物栽培研究

      Volume: 38(2) Pages: 10-16

    • NAID

      40022285241

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] マオウ属植物の栽培研究(第8報)旧国立衛生試験所が導入し保存されてきたマオウ属植物 Ep-13 の遺伝的背景について2016

    • Author(s)
      安藤広和、北村雅史、佐々木陽平、北岡文美代、御影雅幸
    • Journal Title

      薬用植物栽培研究

      Volume: 38(2) Pages: 1-9

    • NAID

      40022285223

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] マオウ属植物の栽培研究(第7報)圃場栽培株の総アルカロイド含量の経年変化と日局麻黄の生産2016

    • Author(s)
      安藤広和、倪斯然、佐々木陽平、御影雅幸
    • Journal Title

      薬用植物栽培研究

      Volume: 38(1) Pages: 20-27

    • NAID

      40022285373

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 麻黄に含まれるエフェドリンの簡易測定法の開発2018

    • Author(s)
      織田枝里子、安藤広和、佐々木陽平
    • Organizer
      日本薬学会第138年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 漢方生薬麻黄の煎法による煎液中の成分変化2018

    • Author(s)
      伊藤ほのか、安藤広和、佐々木陽平
    • Organizer
      日本薬学会第138年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 漢方生薬「麻黄」原植物の研究―DNA配列に基づく簡易鑑別法とアルカロイドの局在について―2017

    • Author(s)
      草場大作、北村雅史、安藤広和、佐々木陽平
    • Organizer
      日本薬学会北陸支部
    • Related Report
      2017 Annual Research Report
  • [Presentation] Ephedra 属植物の育種研究2017

    • Author(s)
      安藤 広和、佐々木 陽平、倪 斯然、御影 雅幸
    • Organizer
      日本生薬学会第64回年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Ephedra 属植物 Ep-13 系統株の性質に関する研究2016

    • Author(s)
      草場大作、安藤広和、佐々木陽平、御影雅幸
    • Organizer
      日本生薬学会第63回年会
    • Place of Presentation
      富山
    • Year and Date
      2016-09-24
    • Related Report
      2016 Research-status Report
  • [Presentation] 漢方生薬「麻黄」の国産化研究(第二報)2016

    • Author(s)
      安藤広和、倪斯然、佐々木陽平、安井廣迪、御影雅幸
    • Organizer
      第33回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
  • [Remarks] 金沢大学薬学系 分子生薬学研究室 研究活動

    • URL

      http://www.p.kanazawa-u.ac.jp/~bunshishoyaku/information.html

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2019-03-29  

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