| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
We focused on the fused technology of drug delivery and imaging by using light, which is called "Theranostics". Near-infrared laser which is safe and has high permeability was used for the experiment with liposome which is lipid nanocapsule. We estimated that light-sensitive liposome is accumulated into the cancer tissue and the irradiation of near-infrared laser make the liposomes broken in the site, resulting in the drug release in cancer tissue. We assumed the liposome which contains fluorescence gold nanocluster is also useful for the monitoring of liposome in vitro and in vivo.
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