| Project/Area Number |
16K19177
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical sociology
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| Research Institution | St. Luke's International University |
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Principal Investigator |
HOSHINO Eri 聖路加国際大学, 臨床疫学センター, 講師 (50598521)
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| Research Collaborator |
HAYASHI Kuniyoshi 聖路加国際大学, 専門職大学院公衆衛生学研究科(公衆衛生大学院), 講師
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 胆道閉鎖症 / 早期発見 / 硫酸抱合型胆汁酸 / 便色カラーカード / 携帯アプリ / 費用対効果分析 / ICT / 便色判定システム / スクリーニングシステム / スクリーニング / 便色判別 / パターン認識 / 費用対効果 / 医療社会学 |
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| Outline of Final Research Achievements |
To explore the effective modality for screening biliary atresia, this study includes conducting (1) a retrospective study on evaluating urinary sulfated bile acid (USBA) measure, (2) a prospective study on developing ICT-integrated screening tool, and (3) a cost-effective analysis on different modalities for biliary atresia screening. Ｔhe sensitivity of USBA measurement was 100% and the specificity was 96.2% using the Okinawa cohort study implemented from 2009-2015. As for a prospective study, we developed the iPhone application, "Baby-poop" and it was released in September 2016. The detection algorithm applied in the application was evaluated using 40 stool pictures including 5 cases of disease and both sensitivity and specificity were 100%. A cost-effectiveness analysis of the three screening methods of biliary atresia, a stool color card, USBA measurement method, and a mobile application is being conducted.
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