| Project/Area Number |
16K19213
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pain science
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| Research Institution | Kochi University |
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Principal Investigator |
IZUMI Masashi 高知大学, 教育研究部医療学系臨床医学部門, 助教 (60420569)
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| Research Collaborator |
IWAHORI Yusuke
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 上腕二頭筋長頭腱 / 痛み / 腱板断裂 / 肩痛 / 運動器疼痛 / トランスレーショナルリサーチ |
|---|
| Outline of Final Research Achievements |
Long head of biceps tendon (LHBT) is originated from shoulder joint and run through anterior upper arm. Though LHBT has been recognized as a pain source of shoulder, its characteristics have not been clarified yet and showing various contribution among patients. In this study, we have developed a new human pain model using ultrasound-guided injection of hypertonic saline into LHBT, which demonstrated spreading pain distribution from anterior to posterior shoulder and approximately 30% reduction of shoulder abduction and elbow flexion force without any structural change of tendon.
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| Academic Significance and Societal Importance of the Research Achievements |
腱板断裂は中高年の肩痛をきたす代表疾患であるが、その痛みにはLHBT由来の痛みが混在している可能性が高い。本研究の成果は、LHBT由来の痛みの広がり方や肩・肘の運動機能に与える重要性、および腱板修復術に際して痛みのためにLHBT切除術などの追加処置を行うことの妥当性、有効性を示唆するものである。
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