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Development of optimization system for high-precision radiotherapy using by structure data of planning and image of multi-modality

Research Project

Project/Area Number 16K19233
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Research InstitutionKyushu University

Principal Investigator

Yoshidome Satoshi  九州大学, 大学病院, 診療放射線技師 (70419612)

Research Collaborator ARIMURA Hidetaka  
Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords高精度放射線治療 / 画像誘導放射線治療 / kV-CBCT画像 / 体幹部定位放射線治療 / テンプレートマッチング技術 / kV-CBCT 画像 / 肺定位放射線治療 / 放射線治療技術学 / 適応放射線治療
Outline of Final Research Achievements

Author developed the automated estimation method of the location of tumor in kV-CBCT images. In the results, the proposed method could estimate the location of tumor less than 2 mm in kV-CBCT images. These results were reported in the magazine of medical imaging and information sciences.
Author examined that the proposed method apply to tumor region with rotation and form change. In addition, author considered that the proposed method was supported by machine learning algorithm for applying to organ at risk.

Academic Significance and Societal Importance of the Research Achievements

本研究における提案手法を用いて,実際に放射線治療を行っている際の腫瘍位置を自動的に推定することは,その放射線治療の精度を確認することに繋がり,放射線治療の適切な対象に十分な放射線を投与する一助となる.また,提案手法を基礎として,治療時の腫瘍の位置や状態によって日々の放射線治療を最適化できる可能性が示され,それが実現することで局所腫瘍制御率の向上や正常組織障害の低減につながると考えられる.

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (4 results)

All 2018 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Automated and robust estimation framework for lung tumor location in kilovolt cone-beam computed tomography images for target-based patient positioning in lung stereotactic body radiotherapy2018

    • Author(s)
      Satoshi Yoshidome, Hidetaka Arimura, Kotaro Terashima, Masakazu Hirakawa, Taka-aki Hirose, Junichi Fukunaga, Yasuhiko Nakamura, Hiroshi Honda
    • Journal Title

      Medical Imaging and Information Sciences

      Volume: 35 Issue: 3 Pages: 48-54

    • DOI

      10.11318/mii.35.48

    • NAID

      130007493980

    • ISSN
      0910-1543, 1880-4977
    • Year and Date
      2018-09-28
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Presentation] Automated estimation framework for lung tumor location in kilovolte cone-beam computed tomography images for target-based positioning in lung stereotactic body radiotherapy.2018

    • Author(s)
      Satoshi Yoshidome, Hidetaka Arimura, Kotaro Terashima, Masakazu Hirakawa, Taka-aki Hirose, Junichi Fukunaga, Yasuhiko Nakamura
    • Organizer
      the 18th Asia-Oceania Congress of Medical Physics (AOCMP)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Automated Framework for Estimation of Lung Tumor Locations in Kilovolt Cone-beam Computed Tomography Images for Target-based Patient Positioning in Stereotactic Lung Body Radiotherapy2018

    • Author(s)
      Satoshi Yoshidome
    • Organizer
      第74回日本放射線技術学会総会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Automated framework for estimation of lung tumor locations in kV-CBCT images for tumor-based patient positioning in stereotactic lung body radiotherapy2017

    • Author(s)
      Satoshi Yoshidome
    • Organizer
      SPIE medical imaging 2017
    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2020-03-30  

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