| Project/Area Number |
16K19241
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical Physics and Radiological Technology
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| Research Institution | National Institutes for Quantum and Radiological Science and Technology |
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Principal Investigator |
Ahmed Abdella 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 計測・線量評価部, 博士研究員(任常) (30749932)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Discontinued (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | PET / radiation detector / image reconstruction / Computing |
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| Outline of Annual Research Achievements |
The dominant factor that limits the intrinsic spatial resolution of a PET system is the size of the crystal elements in the detector. To increase the sensitivity and achieve high spatial resolution, it is essential to use advanced depth-of-interaction (DOI) detectors and arrange them close to the subject. The DOI detectors help to maintain high spatial resolution by mitigating the parallax error caused by the thickness of the scintillator at the peripheral regions in the field-of-view. As an optimal geometry for a brain PET scanner with high sensitivity and high spatial resolution, we proposed and developed the helmet-chin PET using 54 4-layered DOI detectors consisting of 16×16×4 array of GSOZ scintillator crystals with dimensions of 2.8×2.8×7.5 mm3. All the detectors used in the helmet-chin PET had the same spatial resolution. In this study, we conducted a feasibility simulation of a new add-on detector arrangement for the helmet PET by replacing the chin detector with a segmented crystal cube, having high spatial resolution in all directions, which can be placed inside the mouth. The crystal cube (which we call the mouth-insert detector) has 20×20×20 LYSO crystal segments with dimensions of 1×1×1 mm3. Thus, the scanner is formed by the combination of the helmet and mouth-insert detectors, and is referred to as the helmet-mouth-insert PET. The results show that the sensitivity of the helmet-mouth-insert PET had a comparable sensitivity and an improved spatial resolution near the center of the hemisphere compared to those of the helmet chin PET.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
Simulation study was completed as scheduled.
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| Strategy for Future Research Activity |
H29 plan will have to be changed (shortened) due to the personnel change of the principal investigator, who will leave NIRS for ANSTO (in Australia) by the end of April 2017.
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