Roles of prostaglandin I2 in gastrointestinal functioning in irritable bowel syndrome

• Project/Area Number: 16K19326
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Gastroenterology
• Research Institution: Asahikawa Medical College
• Principal Investigator: Kumei Shima 旭川医科大学, 大学病院, 医員 (00548969)
• Project Period (FY): 2016-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: プロスタグランジン / 過敏性腸症候群 / メタボローム解析 / 内臓痛覚閾値 / プロスタグランジンI２ / IP作動薬 / 腸内細菌 / 内臓痛覚過敏 / 消化器内科

Outline of Final Research Achievements

We examined the effect of prostaglandin I2 on gastrointestinal function in irritable bowel disease by using rats. All results of this experiment will be disclosed after a patent application.

Academic Significance and Societal Importance of the Research Achievements

本研究による成果は、すべて特許出願の可能性があるため、研究成果に関与する内容は現時点では公表しない。