The role of Fusobacterium nucleatum in colorectal carcinoma

Research Project

Project/Area Number	16K19353
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Gastroenterology
Research Institution	Yokohama City University
Principal Investigator	UMEZAWA Shotaro 横浜市立大学, 医学研究科, 客員研究員 (90737678)
Research Collaborator	KOMIYA Yasuhiko
Project Period (FY)	2016-04-01 – 2018-03-31
Project Status	Completed (Fiscal Year 2017)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000) Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords	大腸発がん / 腸内細菌 / Fusobacterium nucleatum / 大腸発癌 / 大腸癌
Outline of Final Research Achievements	We collected sample of saliva, tissue of carcinoma and normal colon mucosa form 60 patients with colorectal carcinoma. We investigated proportion of Fusobacterium genus in the level of species. Proportion of Fusobacterium in colorectal carcinoma tissue and normal colon mucosa were 8.9% and 3.3% respectively. Proportion in carcinoma was significantly high compared with in normal mucosa (p < 0.05).

Report

(3 results)