| Project/Area Number |
16K19521
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurology
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 運動イメージ / 脳卒中 / 片麻痺 / リハビリテーション / 電気生理学 / 臨床神経生理学 |
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| Outline of Final Research Achievements |
The combination of motor imagery and afferent input with electrical stimulation (MI+ES) enhances the excitability of the corticospinal tract compared with motor imagery alone or electrical stimulation alone in healthy subjects. We performed an examination of the therapeutic effects of MI+ES on upper motor function in patients with chronic stroke.Ten patients with chronic stroke demonstrating severe hemiparesis participated. The imagined task was extension of the affected finger. Peripheral nerve electrical stimulation was applied to the radial nerve. MI+ES intervention was conducted for 10 days, and pre- and post-intervention clinical and neurophysiological examinations were compared. Upper motor function was assessed with Fugl-Meyer assessments. These features were significantly improved after MI+ES intervention. Reciprocal inhibition from the forearm extensor to flexor muscle was increased after MI+ES intervention.
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