| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
Mycoplasma pneumoniae infection is known to be accompanied by a variety of complications called extrapulmonary manifestations with a frequency of about 25%, and the translocation of M. pneumoniae to the extrapulmonary site is thought to be partly involved in the development of these extrapulmonary diseases. In this study, we investigated the translocation mechanism of M. pneumoniae across the human bronchial epithelial barrier, and found M. pneumoniae translocates through paracellular or transcellular route without affecting epithelial barrier integrity.
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