• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of diagnostic and therapeutic strategy for inducible uricarias

Research Project

Project/Area Number 16K19722
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dermatology
Research InstitutionKobe University

Principal Investigator

Washio Ken  神戸大学, 医学研究科, 医学研究員 (80770388)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords蕁麻疹 / コリン性蕁麻疹 / 日光蕁麻疹 / 採血検査 / 好塩基球刺激試験 / 汗アレルギー / フローサイトメトリー / アレルギー・ぜんそく / 免疫学 / じんましん / アナフィラキシー
Outline of Final Research Achievements

The investigators sought to develop the diagnostic and therapeutic strategy for inducible urticarias, especially for cholinergic and solar urticaria. During the first year, we have reported that there are specific groups of cholinergic urticaria with palpebral angioedema in which sweat allergy are responsible for disease pathophysiology. Further, we have found that the basophil activation test has higher accuracy for the diagnosis of sweat allergy than the histamine release test. We have also shown the clinical utility of basophil activation test for solar urticaria. Our findings suggested the clinical potency of blood-test based diagnosis of inducible urticarias.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (9 results)

All 2018 2017

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] Anaphylaxis caused by a centipede bite: A “true” type-I allergic reaction2018

    • Author(s)
      Washio Ken、Masaki Taro、Fujii Shotaro、Hatakeyama Mayumi、Oda Yoshiko、Fukunaga Atsushi、Natsuaki Masaru
    • Journal Title

      Allergology International

      Volume: 67 Issue: 3 Pages: 419-420

    • DOI

      10.1016/j.alit.2018.01.005

    • NAID

      130007420802

    • ISSN
      1323-8930, 1440-1592
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A case of eperisone hydrochloride-induced anaphylaxis: A true type I reaction?2017

    • Author(s)
      Miki Yasukoi, Washio Ken, Masakki Taro, Nakata Kaori, Fukunaga Atsushi, Nishigori Chikako
    • Journal Title

      Allergology International

      Volume: 66 Issue: 1 Pages: 152-153

    • DOI

      10.1016/j.alit.2016.07.004

    • NAID

      130005308496

    • ISSN
      1323-8930, 1440-1592
    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Contact anaphylaxis caused by Basic Blue 99 in hair dye2017

    • Author(s)
      Washio Ken、Ijuin Keiko、Fukunaga Atsushi、Nagai Hiroshi、Nishigori Chikako
    • Journal Title

      Contact Dermatitis

      Volume: 77 Issue: 2 Pages: 122-123

    • DOI

      10.1111/cod.12740

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical characteristics in cholinergic urticaria with palpebral angioedema: Report of 15 cases2017

    • Author(s)
      Washio K, Fukunaga A, Onodera M, Hatakeyama M, Taguchi K, Ogura K, Horikawa T, Nishigori C.
    • Journal Title

      Journal of Dermatological Science

      Volume: 85 Issue: 2 Pages: 135-137

    • DOI

      10.1016/j.jdermsci.2016.11.001

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Cholinergic urticaria: epidemiology, physiopathology, new categorization, and management2017

    • Author(s)
      Atsushi Fukunaga, Ken Washio, Mayumi Hatakeyama, Yoshiko Oda, Kanako Ogura, Tatsuya Horikawa, Chikako Nishigori
    • Journal Title

      Clinical Autonomic Research

      Volume: 印刷中 Issue: 1 Pages: 103-113

    • DOI

      10.1007/s10286-017-0418-6

    • NAID

      120006599255

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Case of harlequin ichthyosis with a favorable outcome: Early treatment and novel, differentially expressed, alternatively spliced transcripts of the ATP-binding cassette subfamily A member 12 gene.2017

    • Author(s)
      Washio K, Sumi M, Nakata K, Fukunaga A, Yamana K, Koda T, Morioka I, Nishigori C, Yamanishi.
    • Journal Title

      Journal of Dermatology

      Volume: 印刷中 Issue: 8 Pages: 950-953

    • DOI

      10.1111/1346-8138.13823

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] 高齢者の皮膚疾患における汗の関与の検討2017

    • Author(s)
      鷲尾健, 織田好子, 正木太朗, 藤井翔太郎, 畠山真弓, 福永淳
    • Organizer
      第4回汗と皮膚疾患の研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 汗アレルギー患者における汗によるBATの有用性について2017

    • Author(s)
      織田好子, 鷲尾健, 畠山真弓, 福永淳, 錦織千佳子
    • Organizer
      第47回日本皮膚アレルギー・接触皮膚炎学会総会学術大会・第41回皮膚脈管・膠原病研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ムカデ咬症によるアナフィラキシーの1例2017

    • Author(s)
      鷲尾健, 正木太朗, 藤井翔太郎, 畠山真弓, 福永淳, 夏秋優
    • Organizer
      第47回日本皮膚アレルギー・接触皮膚炎学会総会学術大会・第41回皮膚脈管・膠原病研究会
    • Related Report
      2017 Annual Research Report

URL: 

Published: 2016-04-21   Modified: 2021-01-27  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi