Black-blood magnetic resonance imaging for detection of nodular lung lesions and assessment of interstitial pneumonia

• Project/Area Number: 16K19828
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kyushu University
• Principal Investigator: Kamei Ryotaro 九州大学, 医学研究院, 共同研究員 (70772044)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2016: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
• Keywords: 核磁気共鳴画像法 / MRI / 肺結節 / 間質性肺炎 / 核磁気共鳴 / 呼吸器 / 磁気共鳴画像 / 医療・福祉 / 画像 / 癌 / 臨床

Outline of Final Research Achievements

Black-blood imaging is widely used in magnetic resonance imaging to suppress signals arising from blood flow. It could contribute to improving the conspicuity of lesions within the areas adjacent to blood vessels. The results of our volunteer study suggested that peripheral pulse gating is a feasible method for black-blood lung MR imaging. Systolic phase should be selected to obtain a strong and uniform black-blood effect.
In the clinical study, black-blood lung MR imaging provided an acceptable detection rate for nodular lung lesions compared with CT examination. MR could be a feasible and promising imaging modality in detecting lung nodules.

Research Products

• [Presentation] 2D-Turbo Spin-Echo Sequence with Incremental Trigger Delay Time for Monitoring Vascular Signal Suppression in Peripheral Pulse Gated Black-blood Lung MR Imaging (2017)
  • Author(s): Ryotaro Kamei, Yuji Watanabe, Koji Sagiyama, Sungtak Hong, Satoshi Kawanami, Hiroshi Honda
  • Organizer: ISMRM 25th Annual Meeting
• [Presentation] 2D-TSE Sequence with Incremental Trigger Delay Time for Monitoring Vascular Signal Suppression in PPU-gated Black-blood Lung MR imaging (2017)
  • Author(s): Ryotaro Kamei, Yuji Watanabe, Koji Sagiyama, Sungtak Hong, Satoshi Kawanami, Hiroshi Honda
  • Organizer: The 76th Annual Meeting of the Japan Radiological Society
• [Presentation] Breath-Hold Black-Blood T2-weighted Lung Magnetic Resonance Imaging: Optimization of Blood-Flow Signal Suppression using Peripheral Pulse Unit Gating (2016)
  • Author(s): Kamei R, Watanabe Y, Sagiyama K, Hong S, Kawanami S, Honda
  • Organizer: 102nd Annual Meeting for Radiological Society of North America
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2016-11-27
  • Int'l Joint Research
• [Presentation] Detection of ground-glass opacity lesions using breath-hold black-blood magnetic resonance imaging of the lungs (2016)
  • Author(s): Kamei R, Watanabe Y, Sagiyama K, Hong S, Kawanami S, Honda H
  • Organizer: 102nd Annual Meeting for Radiological Society of North America
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2016-11-27
  • Int'l Joint Research
• [Presentation] Detection of ground-glass opacity lesions using breath-hold black-blood magnetic resonance imaging of the lungs (2016)
  • Author(s): Kamei R, Watanabe Y, Sagiyama K, Kawanami S, Honda H
  • Organizer: 第44回日本磁気共鳴医学会大会
  • Place of Presentation: 埼玉県さいたま市
  • Year and Date: 2016-09-09
• [Presentation] Breath-Hold Peripheral Pulse-Gated Black-Blood T2-Weighted Lung Magnetic Resonance Imaging with the Variable Refocusing Flip Angle Technique (2016)
  • Author(s): Kamei R, Watanabe Y, Sagiyama K, Takemura A, Yoneyama M, Kawanami S, Honda H
  • Organizer: 24th Annual Meeting for International Society for Magnetic Resonance in Medicine
  • Place of Presentation: Singapore
  • Year and Date: 2016-05-07
  • Int'l Joint Research
• [Presentation] Investigating the Optimal Acquisition Time of Black-blood Lung MR with Peripheral Pulse Gating (2016)
  • Author(s): Kamei R, Watanabe Y, Sagiyama K, Kawanami S, Honda H
  • Organizer: 第75回日本医学放射線学会学術集会
  • Place of Presentation: 神奈川県横浜市
  • Year and Date: 2016-04-14