• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Establishment of CT angiography and optimal imaging timing prediction method using small amount contrast medium

Research Project

Project/Area Number 16K19833
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionKyushu University

Principal Investigator

Shirasaka Takashi  九州大学, 大学病院, 診療放射線技師 (00380486)

Project Period (FY) 2016-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords至適撮影タイミング予測法 / 造影剤量低減 / 冠動脈CT / 冠動脈CT angiography / 至適スキャンタイミング / 至適撮影タイミング予測 / 心拍出量 / 時間濃度曲線 / X線 / 放射線 / 画像診断 / 造影剤 / CT
Outline of Final Research Achievements

In this study, we aimed to develop a method to predict the optimal imaging timing for each patient, and to conduct examinations with the minimum amount of contrast medium necessary.
First, we focused on the patient's cardiac function, reviewed the past coronary CT examination, and confirmed that the imaging timing was different depending on the flow speed. Next, the proposed timing prediction method was applied to clinical examinations. We confirmed optimization of imaging timing and improvement of heterogeneity of the contrast enhancement. Furthermore, by combining low tube voltage scanning, which is another contrast agent reduction technology, with the proposed method, we could achieve further contrast medium dose reduction.

Academic Significance and Societal Importance of the Research Achievements

CT検査において、腎機能低下患者への造影剤投与による造影剤腎症が問題となっており、使用造影剤量の低減は、腎負荷を軽減することから重要な課題である。 我々が開発した撮影タイミングを予測法は、造影効果が最大となるタイミングを予測でき、余剰に投与される分の造影剤量を低限することが可能である。また、至適撮影タイミング達成率の向上だけでなく冠動脈の造影効果も不均一性が改善されたことから、冠動脈疾患の診断能向上につながる。

Report

(4 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (6 results)

All 2019 2018 2017 2016

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (5 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Feasible scan timing for 320-row coronary CT angiography generated by the time to peak in the ascending aorta.2019

    • Author(s)
      Shirasaka T, Nagao M, Yamasaki Y, Kojima T, Kondo M, Shimomiya Y, Kamitani T, Honda H
    • Journal Title

      Clinical Imaging

      Volume: 54 Pages: 153-158

    • DOI

      10.1016/j.clinimag.2019.01.005

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 320-row Coronary CT Angiography using a Novel Timing-bolus Protocol and Low-tube Voltage can Reduce Amount of Contrast Media2018

    • Author(s)
      白坂 崇
    • Organizer
      The 74th Annual Meeting of the JSRT Japanese Society of Radiological Technology
    • Related Report
      2018 Annual Research Report
  • [Presentation] Optimal Scan Timing for 320-row Coronary Computed Tomography Angiography (CCTA) Generated by Time to Peak at Ascending Aorta Using a Test-bolus Injection2017

    • Author(s)
      白坂 崇
    • Organizer
      The 73rd scientific assembly and annual meeting of the Japanese Society of Radiological Technology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Optimal scan timing for 320-row coronary computed tomography angiography (CCTA) generated by the time to peak at the ascending aorta using a test-bolus injection2016

    • Author(s)
      白坂 崇
    • Organizer
      Radiological Society of North America (RSNA) 2016 Annual Meeting
    • Place of Presentation
      Chicago McCormick place
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 320列冠動脈CTの至適撮影タイミング:大動脈時間濃度曲線による新たな決定法2016

    • Author(s)
      白坂 崇
    • Organizer
      Society of advanced medical imaging SAMI2016
    • Place of Presentation
      東京 東京コンベンションホール
    • Year and Date
      2016-07-30
    • Related Report
      2016 Research-status Report
  • [Presentation] Relationship Between Cardiac Function and Aortic Peak Time at Coronary CT- Angiography2016

    • Author(s)
      白坂 崇
    • Organizer
      第72回 日本放射線技術学会総会
    • Place of Presentation
      神奈川県 パシフィコ横浜
    • Year and Date
      2016-04-14
    • Related Report
      2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2020-03-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi