| Project/Area Number |
16K20246
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tottori University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 頭頸部癌 / 超音波 / 頸部リンパ節転移 / ARFI / shear wave / エラストグラフィ / 頸部リンパ節転移診断 / リンパ節転移 / shear wave エラストグラフィ / shear wave elastography |
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| Outline of Final Research Achievements |
First, we evaluated the utility of shear wave elastography as an adjunct to diagnose lymph node metastasis of head and neck cancer. The results showed that the shear wave velocities of around 35% of metastatic lymph nodes could be measured in vivo. We, therefore, focused on strain imaging using acoustic radiation force impulse (ARFI) in the next phase. Secondly, we clarified that the novel strain imaging namely ARFI imaging has high sensitivity and high specificity to diagnose metastatic lymph node of head and neck squamous cell carcinoma. The ARFI imaging also showed high reproducibility. Then we invented a new scoring system of the ARFI imaging to diagnose metastatic lymph node of head and neck cancer and clarified the correlation between the images of each score and the pathological structure of metastatic lymph nodes. Finally, our study showed the novel strain imaging (ARFI imaging) is superior to other conventional elastography.
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