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the assessment of molecular pathology and choroid in retinal vein occlusion

Research Project

Project/Area Number 16K20321
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionKagoshima University

Principal Investigator

OTSUKA Hiroki  鹿児島大学, 附属病院, 医員 (20611817)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords網膜静脈閉塞症 / 黄斑浮腫 / 分子病態 / 網膜色素上皮 / 眼科学 / 生体分子
Outline of Final Research Achievements

Purpose: To investigate the effectiveness of surgery for macular edema after retinal vein occlusion.
Methods: We examined the relation between the data obtained by optical coherence tomography and vitreous humor of patients who underwent surgery. Results: 6 eyes of 6 patients who underwent surgery were examined. The average age of patients was 68.3 ± 11.5 years old, the median of corrected visual acuity before surgery was 0.5, the median at 3 months after surgery was 0.7. The median retinal foveal thickness was 191 μm before surgery, and 233 μm at the 3 months after surgery. In 5 eyes of 6 patients, there was no improvement of macular edema by 3 months. In future, we will increase the number of cases, and evaluate between long-term visual acuity and the data of optical coherence tomography and vitreous humor.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (11 results)

All 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (9 results)

  • [Journal Article] Acute bacterial endophthalmitis after scleral buckling surgery with chandelier endoillumination2017

    • Author(s)
      Sakono T, Otsuka H, Shiihara H, Yoshihara N, Sakamoto T
    • Journal Title

      Am J Ophthalmol Case Rep

      Volume: 21 Pages: 7-10

    • DOI

      10.1016/j.ajoc.2017.07.007

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reproducibility and differences in area of foveal avascular zone measured by three different optical coherence tomographic angiography instruments.2017

    • Author(s)
      Shiihara H, Sakamoto T, Yamashita T, Kakiuchi N, Otsuka H, Terasaki H, Sonoda S.
    • Journal Title

      Sci Rep

      Volume: 29 Issue: 1 Pages: 9853-9853

    • DOI

      10.1038/s41598-017-09255-5

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 裂孔原性網膜剥離と黄斑円孔、黄斑前膜の僚眼についての検討2017

    • Author(s)
      大塚寛樹、坂本泰二
    • Organizer
      第121回日本眼科学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 2型黄斑部網膜血管拡張症に黄斑円孔を合併した3例2017

    • Author(s)
      吉永就正、山下敏史、大塚寛樹、土居範仁、坂本泰二
    • Organizer
      第71回日本臨床眼科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 人工血管感染に起因する内因性眼内炎が疑われた1例2017

    • Author(s)
      椎原秀樹、大塚寛樹、坂本泰二
    • Organizer
      23回日本糖尿病眼学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 鹿児島大学における糖尿病網膜症に対する硝子体手術後早期硝子体出血例の経過2017

    • Author(s)
      吉永就正、山下敏史、大塚寛樹、坂本泰二
    • Organizer
      第23回日本糖尿病眼学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 周辺部網膜分離症に合併した網膜剥離と黄斑前膜の2症例2017

    • Author(s)
      大塚寛樹、鮫島誠治、吉永就正、山下敏史、園田祥三、坂本泰二
    • Organizer
      第56回日本網膜硝子体学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 黄斑剥離を伴う裂孔原性網膜剥離に対する硝子体手術後の残存網膜下液の検討2016

    • Author(s)
      大塚 寛樹、坂本 泰二
    • Organizer
      臨床眼科学会
    • Place of Presentation
      国立京都国際会館(京都府、京都市)
    • Year and Date
      2016-11-03
    • Related Report
      2016 Research-status Report
  • [Presentation] 大型黄斑円孔へのinverted ILM flap technique手術とPRN-Posturing法の治療成績2016

    • Author(s)
      山下 敏史、大塚 寛樹、山切 啓太、園田 祥三、坂本 泰二
    • Organizer
      臨床眼科学会
    • Place of Presentation
      国立京都国際会館(京都府、京都市)
    • Year and Date
      2016-11-03
    • Related Report
      2016 Research-status Report
  • [Presentation] 低眼圧を伴う裂孔原性網膜剥離の初回手術についての検討2016

    • Author(s)
      大塚 寛樹、山下 敏史、山切 啓太、園田 祥三、 園田 恭志、坂本 泰二
    • Organizer
      日本眼科学会総会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-04-07
    • Related Report
      2016 Research-status Report
  • [Presentation] 特発性黄斑円孔へのPRN-posturing治療成績と円孔閉鎖時間関連因子についての検討2016

    • Author(s)
      山下 敏史、山下 高明、山切 啓太、大塚 寛樹、園田 祥三、坂本 泰二
    • Organizer
      日本眼科学会総会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-04-07
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2019-03-29  

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