| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
Five-week old male mice were constantly fed either with high fat diet (including 32% fat) or control diet (including 4.6% fat), both of which were commercially available. The body weight and blood sugar levels of the high fat diet-fed mice were increased compared with control diet-fed mice after 3 months, although the animals did not have diabetes. The inflammatory cytokines and macrophage markers were increased in the RPE-choroid samples of the high fat diet-fed mice compared with control diet-fed mice.
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