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Elucidation and clinical application of the palatal muscle function by embryological approach

Research Project

Project/Area Number 16K20354
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionKyoto University

Principal Investigator

KISHIMOTO Hideaki  京都大学, 医学研究科, 助教 (10748271)

Research Collaborator SUZUKI Shigehiko  
KAWAI Katsuya  
YAMADA Shigehito  
IMAI Hirohiko  
MATSUDA Tetsuya  
YONEYAMA Akio  
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords小口蓋神経 / 口蓋帆挙筋 / 口蓋裂 / 鼻咽腔閉鎖機能不全 / 言語成績 / 再建外科学
Outline of Final Research Achievements

We studied the samples of the embryo and fetus at Congenital Anomaly Research Center at Kyoto University and stimulated the lesser palatine nerve in palatoplasty in order to elucidate the cause of the velopharyngeal insufficiency which lasts after palatoplasty. As a result, we gained new knowledge about innervation of the levator veli palatini muscle which is important for the palatal surgery. It is suggested that preserving the lesser palatine nerve which has not been paid attention in palatoplasty may lead to improvement of speech result after palatoplasty. It is thought that the lesser palatine nerve derives from the facial nerve, but this study does not reveal. Therefore, additional work is needed.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (5 results)

All 2018 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (4 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] The lesser palatine nerve innervates the levator veli palatini muscle.2016

    • Author(s)
      Kishimoto H, Matsuura Y, Kawai K, Yamada S, Suzuki S.
    • Journal Title

      Plast Reconstr Surg Glob Open

      Volume: 29;4(9) Issue: 9 Pages: e1044-e1044

    • DOI

      10.1097/gox.0000000000001044

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 小口蓋神経温存の口蓋形成手術2018

    • Author(s)
      岸本英明、三河内章子、竹内真理子、松浦喜貴、野田和男、鈴木茂彦
    • Organizer
      日本形成外科学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The importance of the lesser palatine nerve during palatoplasty2017

    • Author(s)
      Kishimoto Hideaki
    • Organizer
      第13回国際口蓋裂学会
    • Place of Presentation
      チェンナイ(インド)
    • Year and Date
      2017-02-08
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The importance of the lesser palatine nerve during palatoplasty2017

    • Author(s)
      Kishimoto H, Yamada S, Katsube M, Matsuura Y, Kawai K, Suzuki S
    • Organizer
      国際口蓋裂学会
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 当科における口蓋形成術後の言語成績について2017

    • Author(s)
      岸本英明、三河内章子、竹内真理子、松浦喜貴、野田和男、益岡弘、河合勝也、鈴木茂彦
    • Organizer
      日本形成外科学会総会
    • Related Report
      2017 Annual Research Report

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Published: 2016-04-21   Modified: 2019-03-29  

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