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Making of a neurodifferentiation amnion sheet of dental pulp cell aiming at treatment of the dental pulp disease

Research Project

Project/Area Number 16K20542
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Dental engineering/Regenerative dentistry
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

honjo kenichi  京都府立医科大学, 医学(系)研究科(研究院), 特任助教 (00756877)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords歯髄由来細胞 / 羊膜 / 培養細胞シート / 神経分化誘導 / 再生医学 / 細胞・組織 / 免疫学 / トランスレーショナルリサーチ
Outline of Final Research Achievements

Making of a neurodifferentiation amnion sheet of dental pulp cell and aiming for the development of the new treatment for dental pulp disease. I cultured dental pulp cell on the amnion and differentiated to nerve it. I transplanted a culture sheet to the molar tooth of approximately 20 weeks of age Fischer 344 nude rats (male). Approximately four weeks later, performing examination of the histologic immunohistology, accepted the local existence of the culture sheet. But the morphological change of the organization did not accept it.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (2 results)

All 2017

All Presentation (2 results)

  • [Presentation] 神経分化誘導した羊膜上培養歯髄由来細胞シートの作成2017

    • Author(s)
      山本俊郎、本城賢一、堀口智史、佐藤良樹、遠藤悠美、足立圭司、大迫文重、雨宮傑、中村亨、金村成智
    • Organizer
      第147回日本歯科保存学会 2017年度秋季学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 羊膜上培養歯髄由来細胞シートの神経分化誘導2017

    • Author(s)
      本城賢一、山本俊郎、佐藤良樹、足立圭司、大迫文重、雨宮傑、金村成智
    • Organizer
      平成29年度 日本歯周病学会60周年記念京都大会
    • Related Report
      2017 Annual Research Report

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Published: 2016-04-21   Modified: 2019-03-29  

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