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Anticancer agent-resistant mechanism elucidation and new cure development through cytokine in oral cancer.

Research Project

Project/Area Number 16K20593
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionKumamoto University

Principal Investigator

Nakagawa Yoshihiro  熊本大学, 医学部附属病院, 非常勤診療医師 (70732741)

Co-Investigator(Renkei-kenkyūsha) Nakayama Hideki  熊本大学, 医学部附属病院, 教授 (70381001)
Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
KeywordsSAS / 抗癌剤耐性 / fibronectin / 口腔扁平上皮癌 / 細胞外基質 / 癌
Outline of Final Research Achievements

I studied anticancer agent-resistant mechanism にの elucidation in fibronectin, but cell proliferation was not able to weigh it by the restraint experiment strong expression of fibronectin because a difference had appeared. I performed expression of integrin receptor restraint, strong expression, but was not able to weigh it because a difference had gone to a cell shape, the adhesion. I was not able to elucidate it about anticancer agent-related mechanism in the direct participation of fibronectin than the above.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2019-03-29  

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