Relationship between physical activity and mandibular growth: morphometric analysis of human facial skeleton and experiment using a mouse voluntary climbing exercise model
| Project/Area Number |
16K20639
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
Shimizu Yasuhiro 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (60631968)
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| Research Collaborator |
AOKI kazuhiro
KAIFU yousuke
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 身体運動 / 咀嚼刺激 / 顎骨成長 / 顎骨形態 / 咬筋 / 顎顔面形態 / 咀嚼運動 / 身体運動刺激 / マイクロCT |
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| Outline of Final Research Achievements |
We have shown that physical activity during growth period may affect morphological changes in the mandible using by a mouse voluntary climbing exercise model.
In human specimens, morphometric analysis between high ranked warrior and townspeople in the Edo period and between races in modern women (Japanese and Spanish) suggested that differences in masticatory muscle movement may affect morphological changes in the mandible.
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| Academic Significance and Societal Importance of the Research Achievements |
研究成果として成長期における生活習慣が顎骨形態に影響を与える可能性が示唆された。
歯科領域において成長期に顎骨の成長をコントロールすることは正常咬合を獲得する上で重要であるため、顎骨成長に与える要因を明らかにすることは臨床的意義が高い。顎骨の成長を鑑みた成長期における生活習慣の重要性が明らかとなれば、将来の応用展開に向けた学術基盤を構築することとなり、社会的意義は大きいと考える。
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Low-intensity pulsed ultrasound reduces periodontal atrophy in occlusal hypofunctional teeth.2017
Author(s)
Kasahara Y, Usumi-Fujita R, Hosomichi J, Kaneko S, Ishida Y, Shibutani N, Shimizu Y, Okito A, Oishi S, Kuma Y, Yamaguchi H, Ono T.
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Journal Title
The ANGLE ORTHODONTIST
Volume: 印刷中
Issue: 5
Pages: 709-716
DOI
Related Report
Peer Reviewed / Open Access
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