Development of a method to improve QOL of elderly people by targeting new root caries bacterial species

Research Project

Project/Area Number	16K20696
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Social dentistry
Research Institution	Kagoshima University
Principal Investigator	Obata Junko 鹿児島大学, 医歯学域歯学系, 助教 (70759448)
Project Period (FY)	2016-04-01 – 2018-03-31
Project Status	Completed (Fiscal Year 2017)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords	P. acidifaciens / 根面う蝕 / 象牙質う蝕 / 高齢者 / Propionibacterium属 / う蝕細菌 / 予防歯科学 / う蝕象牙質
Outline of Final Research Achievements	Propionibacterium acidifaciens (P. acidifaciens) has newly been isolated from carious dentin lesions, but the cariogenicity of the organism remains unclear. The purpose of this study was to investigate the characteristics of the organism and their relationship to initiation of dentinal caries. P. acidifaciens was not aggregated with saliva. It had ability to adhere to hydroxyapatite beads. It had high ability to bind to collagen. It showed low resistance to hydrogen peroxide-producing bacteria. Biofilm formation was affected in acid environment. The results suggest the reasons for existence of the organism under the specific environment of carious dentin lesions.

Report

(3 results)