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Real time functional brain network diagnosis combining with electrocorticogram and evoked potentials

Research Project

Project/Area Number 16K20887
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Brain biometrics
Neurosurgery
Research InstitutionAsahikawa Medical College

Principal Investigator

Ogawa Hiroshi  旭川医科大学, 医学部, 助教 (60632536)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
KeywordsElectrocorticography / High gamma activity / Electrical stimulation / CCEP / Brain machine interface / Electrocorticogram / Functional brain mapping / Brain function / Awake surgery / Epilepsy surgery / 脳・神経
Outline of Final Research Achievements

We have studied the feasibility of real-time HGA mapping in clinical use. HGA mapping allows us to rapidly and precisely map areas without the risk of evoking seizure. Real-time HGA mapping has the potential to be an alternative to ECS mapping. We found the facial cognition system in right temporal base applying HGA mapping and ECS mapping. The result was published in PNAS and that was approved world widely. The main problem of HGA mapping technique is that the patients with severe aphasia or bad consciousness are excluded from the study because they are not able to perform language tasks sufficiently. To overcome this limitation, we developed a passive language mapping technique combining task-related high gamma activity (HGA) and cortico-cortical evoked potential (CCEP). We have already reported a single case report of the combined mapping technique. Further study of HGA mapping may provide new possibilities for functional brain mapping.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (11 results)

All 2018 2017 2016

All Journal Article (5 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 5 results,  Open Access: 4 results) Presentation (6 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] Real-Time Detection and Discrimination of Visual Perception Using Electrocorticographic Signals.2018

    • Author(s)
      Kapeller C, Ogawa H, Schalk G, Kunii N, Coon WG, Scharinger J, Guger C, Kamada K.
    • Journal Title

      J Neural Eng.

      Volume: 15(3) Issue: 3 Pages: 1-16

    • DOI

      10.1088/1741-2552/aaa9f6

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 非覚醒下で言語機能マッピングを施行した脳腫瘍手術症例2018

    • Author(s)
      小川 博司、広島 覚、安栄 良悟、真田 隆広、竹内 文也、鎌田 恭輔
    • Journal Title

      CI研究

      Volume: in press

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Facephenes and rainbows: Causal evidence for functional and anatomical specificity of face and color processing in the human brain2017

    • Author(s)
      Schalk Gerwin、Kapeller Christoph、Guger Christoph、Ogawa Hiroshi、Hiroshima Satoru、Lafer-Sousa Rosa、Saygin Zeynep M.、Kamada Kyousuke、Kanwisher Nancy
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 114 Issue: 46 Pages: 12285-12290

    • DOI

      10.1073/pnas.1713447114

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Clinical Impact and Implication of Real-Time Oscillation Analysis for Language Mapping2017

    • Author(s)
      Ogawa H, Kamada K, Kapeller C, Pruckle R, Takeuchi F, Hiroshima S, Anei R, Guger C
    • Journal Title

      World Neurosurgery

      Volume: 97 Pages: 123-131

    • DOI

      10.1016/j.wneu.2016.09.071

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Passive language mapping combining real-time oscillation analysis with cortico-cortical evoked potentials for awake craniotomy2016

    • Author(s)
      Tamura Y, Ogawa H, Kapeller C, Prueckl R, Takeuchi F, Anei R, Rittaccio A, Guger C, *Kamada K
    • Journal Title

      J neurosurgery

      Volume: 印刷中 Issue: 6 Pages: 1580-1588

    • DOI

      10.3171/2015.4.jns15193

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] 高周波律動を用いた側頭葉底部に対する脳機能マッピングの有用性2018

    • Author(s)
      小川 博司、 高島 諒、広島 覚、鎌田 恭輔
    • Organizer
      てんかん外科学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] リアルタイムHGAマッピングを用いた言語課題別の経時的活動変化2018

    • Author(s)
      小川 博司、 竹内 文也、佐藤 正夫、 広島 覚、鎌田 恭輔
    • Organizer
      CI学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Clinical Application of Electrocorticography to the Functional Brain Mapping.2018

    • Author(s)
      Hiroshi Ogawa, Christoph Kapeller, Robert Prückl, Johannes Grünwald, Kyousuke Kamada, Christoph Guger
    • Organizer
      Neurotalk2018
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 非覚醒下での言語機能マッピング2017

    • Author(s)
      小川 博司、佐藤 広崇、田村 有希恵、安栄 良悟、竹内 文也 、鎌田 恭輔
    • Organizer
      日本脳神経CI学会総会
    • Place of Presentation
      鹿児島サンロイヤルホテル
    • Year and Date
      2017-03-03
    • Related Report
      2016 Research-status Report
  • [Presentation] てんかん外科手術における脳皮質脳波の臨床応用2017

    • Author(s)
      小川 博司、広島 覚、竹内 文也、鎌田 恭輔
    • Organizer
      日本てんかん外科学会
    • Place of Presentation
      ナレッジキャピタルコングレコンベンションセンター
    • Year and Date
      2017-01-26
    • Related Report
      2016 Research-status Report
  • [Presentation] 覚醒下手術における高周波律動を用いた言語機能マッピング2016

    • Author(s)
      小川 博司, 竹内 文也, 広島 覚, 鎌田 恭輔
    • Organizer
      日本脳神経外科学会総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2016-09-29
    • Related Report
      2016 Research-status Report

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Published: 2016-04-21   Modified: 2019-03-29  

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