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Investigation of behavior and cortical network for social causal attribution in primates

Research Project

Project/Area Number 16K21042
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Brain biometrics
Basic / Social brain science
Research InstitutionNiigata University

Principal Investigator

Adachi Yusuke  新潟大学, 医歯学系, 助教 (40625646)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords認知神経科学 / マカクザル / 神経科学 / 大脳皮質
Outline of Final Research Achievements

In daily life we always attribute the causes of personal events to self, other agents, or other entities. Because invasive researches in animals are indispensable to clarify the details of the neural mechanism of social causal attribution, it is necessary to construct a nonverbal behavioral task that is applicable to non-human animals. We constructed a behavior experiment system in which macaque monkeys had to judge what was the cause of good or bad events. It was confirmed that monkeys could adapt to the situation where the causal relationship changed in qualitative or quantitative manners. We also performed functional magnetic resonance imaging experiments in humans with an equivalent task and examined the brain regions related to causal attribution in this task.

Academic Significance and Societal Importance of the Research Achievements

社会的な原因帰属に偏りが生じることは健常者においてもしばしばあることだが、とくに統合失調症などの精神疾患で出来事の原因帰属に障害が伴うことが知られている。動物に適用可能な社会的原因帰属行動実験系を構築し、またヒトにおいて機能画像法を用いた関連脳領域の検討を行ったことにより、動物において侵襲的手法を用いたさらに詳細な生理学研究により社会的原因帰属行動の神経機構を解明する基盤となり、原因帰属の障害がみられる精神疾患の神経生理学的理解につながることが期待される。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (8 results)

All 2019 2018 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (6 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Dynamic laminar rerouting of inter-areal mnemonic signal by cognitive operations in primate temporal cortex2018

    • Author(s)
      Takeda, M., Hirabayashi, T., Adachi, Y., and Miyashita, Y.
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 4629-4629

    • DOI

      10.1038/s41467-018-07007-1

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Causal neural network of metamemory for retrospection in primates2017

    • Author(s)
      Miyamoto, K., Osada, T., Setsuie, R., Takeda, M., Tamura, K., Adachi, Y., and Miyashita, Y.
    • Journal Title

      Science

      Volume: 355 Issue: 6321 Pages: 188-193

    • DOI

      10.1126/science.aal0162

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] マカクザル及びヒトの質的・量的な因果構造理解に基づく自己に関わる出来事の原因帰属行動2019

    • Author(s)
      阿部湧,足立雄哉,田村滉樹,齊藤孝臣,飯島淳彦,長谷川功
    • Organizer
      第66回 中部日本生理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Neural activations linking dual-step merge processes during comprehension of sequentially presented letterstrings: an fMRI study.2019

    • Author(s)
      Kasedo R, Iijima A, Nakahara K, Adachi Y, Homae F, Hashimoto R, Yamamoto K, Fukuda M, Shirozu H, Hasegawa I
    • Organizer
      The 42nd Annual Meeting of the Japan Neuroscience Society Meeting
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 自己に関わる出来事の原因判断行動を検出するマカクザル実験パラダイム.2018

    • Author(s)
      田村 滉樹, 足立 雄哉, 阿部 湧, 飯島 淳彦, 長谷川 功.
    • Organizer
      生体医工学シンポジウム
    • Related Report
      2018 Research-status Report
  • [Presentation] fMRI を用いた文字から文への構造化プロセスに関わる脳領域の探索.2018

    • Author(s)
      渡邊 諒太, 飯島 淳彦, 中原 潔, 白水 洋史, 福多 真史, 足立 雄哉, 長谷川 功.
    • Organizer
      生体医工学シンポジウム
    • Related Report
      2018 Research-status Report
  • [Presentation] fMRIによる逐語的な文の階層構造築過程における脳内機構の解明2017

    • Author(s)
      岡本 俊輔, 渡邊 諒太, 飯島 淳彦, 中原 潔, 足立 雄哉, 長谷川 功
    • Organizer
      生体医工学シンポジウム2017
    • Related Report
      2017 Research-status Report
  • [Presentation] Hierarchical prefrontal network arising from frontal pole area 10 during contextual memory retrieval in macaques.2016

    • Author(s)
      Osada T, Adachi Y, Miyamoto K, Jimura K, Setsuie R, Watanabe T, Miyashita Y
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2021-02-19  

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