Nuclear grading of non-small cell lung cancer assessed by an image analysis system

• Project/Area Number: 16K21201
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Human pathology; Laboratory medicine
• Research Institution: Kagawa University
• Principal Investigator: Kadota Kyuichi 香川大学, 医学部附属病院, 助教 (70448356)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 肺癌 / 病理 / 細胞診 / 細胞核 / 核グレード

Outline of Final Research Achievements

Our comprehensive evaluation of cytological nuclear morphometry suggests that nuclear size is an important prognostic marker in patients with advanced unresectable NSCLC.

Research Products

• [Journal Article] A Grading System Combining Tumor Budding and Nuclear Diameter Predicts Prognosis in Resected Lung Squamous Cell Carcinoma. (2017)
  • Author(s): Kadota K1, Miyai Y, Katsuki N, Kushida Y, Matsunaga T, Okuda M, Yokomise H, Kanaji N, Bandoh S, Haba R.
  • Journal Title: Am J Surg Pathol Volume: 41 Pages: 750-760
  • Peer Reviewed
• [Journal Article] Nuclear grade based on transbronchial cytology is an independent prognostic factor in patients with advanced, unresectable non-small cell lung cancer. (2016)
  • Author(s): Kadota K, Miyai Y, Katsuki N, Kushida Y, Matsunaga T, Okuda M, Yokomise H, Kanaji N, Bandoh S, Haba R
  • Journal Title: Cancer Cytopathol Volume: 124 Issue: 9 Pages: 630-640
  • DOI: 10.1002/cncy.21736
  • Peer Reviewed