| Project/Area Number |
16K21225
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied anthropology
Applied health science
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| Research Institution | Hokkaido University (2017)
Kyushu University (2016) |
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Principal Investigator |
LEE SANGIL 北海道大学, 工学研究院, 助教 (70738880)
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| Research Collaborator |
HIGUCHI Shigekazu
OHASHI Michihiro
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 概日リズム / ヒト / 社会的時差ボケ / 栄養 / メラトニン / フィールド / 光 / 光環境 / 睡眠習慣 / 覚醒度 / フィールド実験 / 光の非視覚的作用 / 睡眠 |
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| Outline of Final Research Achievements |
The aim of this study was to determine whether L-serine intake can promote circadian photoentrainment in real life. Thirty-five healthy university students (18 males and 17 females, 21.5 ± 2.2 yrs) participated in a four-week field study. During the experiment, we did not control participants’ sleep habits and social schedules. The participants were randomly divided into two groups (L-serine and placebo groups, double-blinded). In the L-serine group, a trend of phase advance was found after intake for 10 days, but it was not significantly greater than that of the placebo group. However, the L-serine group showed a relative circadian advance to sleep phase, whereas the placebo groups did not. In the data obtained from winter experiment, we found a greater circadian advance in the L-serine group compared with that in the placebo group.
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