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Cell growth in hypergravity using centrifugal microfluidic device and its application to cell culture systems

Research Project

Project/Area Number 16K21493
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Nano/Microsystems
General pharmacology
Research InstitutionOsaka University

Principal Investigator

Tonomura Wataru  大阪大学, 産業科学研究所, 特任助教(常勤) (50581493)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsマイクロ・ナノ流体デバイス / メカノバイオロジー / マイクロ・ナノデバイス / 流体工学 / 細胞・組織
Outline of Final Research Achievements

Centrifugal microfluidic devices were developed in order to observe single-cell growth in environment of hypergravity. Qualitative analysis of microparticle behavior inside centrifugal microfluidic channels in environment of hypergravity, quantitative analysis of microparticle behavior inside centrifugal microfluidic channels in environment of hypergravity, and evaluation of deformability of single cell (blood cell) in centrifugal microfluidic channels, which was fabricated by softlithography technique using silicon rubber or nanoimprint technique using COP film, were observed.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • Research Products

    (1 results)

All 2017

All Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Dual-height fluidic-channel-integrated micropore sensor for high-throughput single-particle detections2017

    • Author(s)
      W. Tonomura, M. Tsutsui, K. Yokota, A. Arima, M. Taniguchi, T. Kawai
    • Organizer
      The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2019-03-29  

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