| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Several studies have clarified that the transition among quasi-stable species with their characteristic structures is essential for protein functioning. The purposes of this study are 1) clarification of an essential role of hydrogen-bond network in the transitions; 2) optical control of the transitions with mid-infrared laser pulses.
A femtosecond time-resolved spectroscopy system with high sensitivity was developed based on reaction-trigger UV pulse, tunable mid-infrared pump pulse, and broadband probe pulse. Although a signal change induced by the mid-infrared pulse was clearly observed, it is suggested that the change does not come from the contribution of excited state or intermediate states.
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