| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Outline of Final Research Achievements |
Distribution pattern of parvalbumin (PV)-positive neurons that are major GABAergic interneurons in the hippocampus and neocortex was explored using immunohistochemical method and mathematical analysis. PV neurons in the CA1 region of the hippocampus were distributed in both the stratum pyramidale and a thin lamina at the border between the stratum oriens and alveus. Somata of the latter population showed a random pattern with their dendrites extending in the same lamina and forming gap junction-coupled plexus. PV neurons in the dentate gyrus were also distributed in a thin lamina between the granule cell layer and hilus, showed a random pattern, and formed gap junction-coupled dendritic nets in the lamina. These structures are thought to facilitate flexible regulation of neuronal activities involved in memory formation.
|
