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The core unit supporting research, communication, network and young scientists in the cancer research field

Research Project

Project/Area Number 17012024
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionJapanese Foundation For Cancer Research

Principal Investigator

NAKAMURA Takuro  Japanese Foundation For Cancer Research, 発がん研究部, 部長 (00180373)

Co-Investigator(Kenkyū-buntansha) IMAMURA Takeshi  財団法人癌研究会, 癌研究所生化学部, 部長 (70264421)
MIYAZONO Kouhei  東京大学, 大学院・医学系研究科, 教授 (90209908)
ISHIKAWA Fuyuki  京都大学, 大学院・生命科学研究科, 教授 (30184493)
MATUDA Michiyuki  京都大学, 大学院・医学研究科, 教授 (10199812)
Project Period (FY) 2005 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥250,000,000 (Direct Cost: ¥250,000,000)
Fiscal Year 2009: ¥46,900,000 (Direct Cost: ¥46,900,000)
Fiscal Year 2008: ¥46,900,000 (Direct Cost: ¥46,900,000)
Fiscal Year 2007: ¥46,900,000 (Direct Cost: ¥46,900,000)
Fiscal Year 2006: ¥46,900,000 (Direct Cost: ¥46,900,000)
Fiscal Year 2005: ¥62,400,000 (Direct Cost: ¥62,400,000)
Keywords国際交流 / 若手支援 / 広報支援 / 青少年育成 / 広報活動
Research Abstract

The core unit (Chukaku Kyoten) supported researches in the priority area for cancer research. The unit consisted of committees for support of young scientists, international affairs, public relations and youth education, and promoted research activities of young scientists, traveling of researchers to abroad, international workshop, publication and internet service of research activities and youth education for cancer.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (27 results)

All 2008 2007 2006 2005 Other

All Journal Article (21 results) (of which Peer Reviewed: 10 results) Presentation (1 results) Remarks (4 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] BCL11A is a SUMOylated protein and recruits SUMO-conjugation enzymes in its muclear body.2008

    • Author(s)
      Kuwata T, Nakamura T.
    • Journal Title

      Genes Cells 13

      Pages: 931-940

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.2008

    • Author(s)
      Fukunaga E, Inoue Y, komiya S, Horiguchi K, Goto K, Saitoh M, MiyazawaK, Koinuma D, Hanyu A, Imamura T,
    • Journal Title

      J Biol Chem 283

      Pages: 35660-35667

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-b signaling.2008

    • Author(s)
      Ikushima H. Komuro A, IsogayaK, Shinozaki M, Hellman U, Miyazawa K, Miyazono K.
    • Journal Title

      EMBO J 27

      Pages: 2955-2965

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.2008

    • Author(s)
      Miyoshi T, Kanoh J, Saito M, Ishikawa F.
    • Journal Title

      Science 320

      Pages: 1341-1344

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imaging of Rab5 activity identifies essential regulators for phagosome maturation.2008

    • Author(s)
      Kitano M, Nakaya M, Nakamura T. Nagata S. Matsuda M.
    • Journal Title

      Nature 453

      Pages: 214-245

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pitx2 prevents osteoblastic trans-differentiation of myoblasts by bone morphogenetic proteins.2008

    • Author(s)
      Hayashi M, Maeda S, Aburatani H, et. al.
    • Journal Title

      J Biol Chem 283

      Pages: 565-571

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of candidate cooperative genes of the Apc mutation in transformation of the colon epithelial cell by retroviral insertional mutagenesis.2008

    • Author(s)
      Tanaka M, Jin G, Yamazaki Y, et. al.
    • Journal Title

      Cancer Sci. 99

      Pages: 979-985

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tribl and Evil cooperate with Hoxa and Meisl in myeloid leukemogenesis.2007

    • Author(s)
      Jin G, Yamazaki Y, Takuwa M, et. al.
    • Journal Title

      Blood 109

      Pages: 3998-4005

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of NGF-stimulated PC12 cells.2007

    • Author(s)
      Aoki K, Nakamura T, Inoue T, et. al.
    • Journal Title

      J Cell Biol 177

      Pages: 817-827

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transforming growth factor-b promotes survival of mammary carcinoma cells through induction of anti-apoptotic transcription factor DEC1.2007

    • Author(s)
      Ehata S, Hanyu A, Hayashi M, et. al.
    • Journal Title

      Cancer Res. 67

      Pages: 9694-9703

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Improvement of cancer-targeting therapy using nanocarriers for intractable solid tumors by inhibition of TGF-6 signaling.2007

    • Author(s)
      Kano M.R., Bae Y., Mivazono K.et al.
    • Journal Title

      Proc Natl Acad Sci USA 104・9

      Pages: 3460-3465

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation.2006

    • Author(s)
      Kawamura-Saito M., Yamazaki Y., Kaneko K., Kawaguchi N., Nakamura T.et al.
    • Journal Title

      Hum Mot Genet 15・13

      Pages: 2125-2137

    • Related Report
      2006 Annual Research Report
  • [Journal Article] CCAAT/enhancer-binding protein homologous protein (CHOP) regulates osteoblast differentiation.2006

    • Author(s)
      Shirakawa K., Maeda M., Gotoh T., Imamura T.et al.
    • Journal Title

      Mol Cell Biol 26・16

      Pages: 6105-6116

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Loss of Linker Histone H1 in Cellular Senescence.2006

    • Author(s)
      Funayama R., Saito M., Tanobe H., Ishikawa F.
    • Journal Title

      J. Cell Biol 175・6

      Pages: 869-880

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.2006

    • Author(s)
      Terai K., Matsuda M.
    • Journal Title

      EMBO J 25・15

      Pages: 3556-3564

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cell-cycle-dependent Xenopus TRF1 recruitment to telomere chromatin regulated by Polo-like kinase.2006

    • Author(s)
      Nishiyama A, Muraki K, Saito M, Ohsumi K, Kishimoto T, Ishikawa F.
    • Journal Title

      EMBO J 25・3

      Pages: 575-584

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model.2005

    • Author(s)
      Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, Osato M, Ito Y, Kroon E, Sauvageau G, Nakamura T.
    • Journal Title

      Blood 105

      Pages: 784-793

    • Related Report
      2005 Annual Research Report
  • [Journal Article] EWSR1 is fused to POU5F1 in a bone tumor with translocation t(6;22)(p21;q12).2005

    • Author(s)
      Yamaguchi S, Yamazaki Y, Ishikawa Y, Kawaguchi N, Mukai H, Nakamura T
    • Journal Title

      Chromosomes Cancer 43

      Pages: 217-222

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta.2005

    • Author(s)
      Tojo M, Hamashima Y, Hanyu A, Kajimoto T, Saitoh M, Miyazono K, Node M, Imamura T.
    • Journal Title

      Cancer Sci 96

      Pages: 791-800

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.2005

    • Author(s)
      Azuma H, Ehata S, Miyazaki H, Watabe T, Miyazono K. et al.
    • Journal Title

      J.Natl.Cancer Inst 97・23

      Pages: 1734-1746

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Dynamics of the RAS/ERK map kinase cascade as monitored by fluorescence probes.

    • Author(s)
      Fujioka A, Terai K, Itoh RE, Aoki K, Nakamura T, Kuroda S, Nishida E, Matsuda M.
    • Journal Title

      J Biol Chem (In press)

    • Related Report
      2005 Annual Research Report
  • [Presentation] Molecular mechanisms of Hoxa9/Meisl-induced myeloid leukemogenes is2007

    • Author(s)
      中村卓郎
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-10-04
    • Related Report
      2007 Annual Research Report
  • [Remarks]

    • URL

      http://gantoku3.umin.jp/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://gantoku3.umin.jp/about/chukaku.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://gantoku3.umin.jp/about/chukaku.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://gantoku3.umin.jp/about/chukaku.html

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] TGF-βシグナル阻害剤と抗腫瘍剤の組み合せ使用2006

    • Inventor(s)
      宮園浩平 他7名
    • Industrial Property Number
      2006-024843
    • Filing Date
      2006-02-01
    • Related Report
      2006 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2018-03-28  

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