| Budget Amount *help |
¥360,400,000 (Direct Cost: ¥360,400,000)
Fiscal Year 2009: ¥72,500,000 (Direct Cost: ¥72,500,000)
Fiscal Year 2008: ¥72,500,000 (Direct Cost: ¥72,500,000)
Fiscal Year 2007: ¥72,500,000 (Direct Cost: ¥72,500,000)
Fiscal Year 2006: ¥72,500,000 (Direct Cost: ¥72,500,000)
Fiscal Year 2005: ¥70,400,000 (Direct Cost: ¥70,400,000)
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| Research Abstract |
It is now well established that chromosomal aberrations play a major role in carcinogenesis. Yet, the precise mechanisms how aberrant chromosomes are formed remain unknown. In this study, we focused on the telomere, the terminal domain of linear chromosomes. First, we identified novel chromatin structures at telomeres, and next we examined how chromosomes would become unstable in dysfunctional telomeres.
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