| Budget Amount *help |
¥71,500,000 (Direct Cost: ¥71,500,000)
Fiscal Year 2009: ¥14,300,000 (Direct Cost: ¥14,300,000)
Fiscal Year 2008: ¥14,300,000 (Direct Cost: ¥14,300,000)
Fiscal Year 2007: ¥14,300,000 (Direct Cost: ¥14,300,000)
Fiscal Year 2006: ¥14,300,000 (Direct Cost: ¥14,300,000)
Fiscal Year 2005: ¥14,300,000 (Direct Cost: ¥14,300,000)
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| Research Abstract |
This study focused on investigating the molecular basis of epigenetic cell deregulation in cancer, through analyzing the abnormalities of nuclear factors including methylated DNA binding protein MBD1 and its associated factor MCAF1, CTCF-mediated chromatin insulator, HMGA proteins, SUMOylation of nuclear proteins, and nuclear substructure. These findings strongly contribute to promoting cancer diagnosis and therapy.
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