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Fundamental Network of Genes and Proteins for Bacterial Cell Growth

Research Project

Project/Area Number 17017026
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionNara Institute of Science and Technology

Principal Investigator

OGASAWARA Naotake  Nara Institute of Science and Technology, 情報科学研究科, 教授 (10110553)

Co-Investigator(Kenkyū-buntansha) MORI Hirotada  奈良先端科学技術大学院大学, バイオサイエンス研究科, 教授 (90182203)
KANAYA Shigehiko  奈良先端科学技術大学院大学, 情報科学研究科, 教授 (90224584)
OSHIMA Taku  奈良先端科学技術大学院大学, 情報科学研究科, 助教 (50346318)
ISHIKAWA Shu  奈良先端科学技術大学院大学, 情報科学研究科, 助教 (30359872)
小林 和夫  奈良先端科学技術大学院大学, 情報科学研究科, 助手 (70324978)
Project Period (FY) 2005 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥200,400,000 (Direct Cost: ¥200,400,000)
Fiscal Year 2009: ¥41,700,000 (Direct Cost: ¥41,700,000)
Fiscal Year 2008: ¥40,100,000 (Direct Cost: ¥40,100,000)
Fiscal Year 2007: ¥39,600,000 (Direct Cost: ¥39,600,000)
Fiscal Year 2006: ¥39,000,000 (Direct Cost: ¥39,000,000)
Fiscal Year 2005: ¥40,000,000 (Direct Cost: ¥40,000,000)
Keywords細菌細胞 / 枯草菌 / 大腸菌 / 転写制御 / ChIP-chip解析 / 必須タンパク質 / タンパク質複合体 / システム生物学 / 遺伝子発現制御 / タイリングチップ / 細胞システム
Research Abstract

Towards elucidation of fundamental networks of genes and proteins supporting growth of bacterial cells, we analyzed two model bacteria, Bacillus subtilis and Escherichia coli, using new methodologies, such as ChIP-chip analysis using a tiling chip and protein complex analysis using mass spectrometry. As the results, we obtained many new findings concerning new functions of essential genes, functional network of essential proteins, transcriptional regulatory network by transcription factors and nucleoid proteins, cell cycle regulation by nucleoid protein, and metabolome dynamics.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (96 results)

All 2010 2009 2008 2007 2006 2005

All Journal Article (49 results) (of which Peer Reviewed: 38 results) Presentation (43 results) Book (4 results)

  • [Journal Article] Update on the Keio collection of Escherichia coli single-gene deletion mutants.2009

    • Author(s)
      Yamamoto, N., Nakahigashi, K., Nakamichi, T., Yoshino, M., Takai, Y., Touda, Y., Furubayashi, A., Kinjo, S., Dose, H., Hasegawa, M., Datsenko, K.A., Nakayashiki, T., Tomita, M., Wanner, B.L., Mori H.
    • Journal Title

      Mol Syst Biol 5,335

    • NAID

      120005830849

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of transcriptional responses in Bacillus subtilis cells to an antibiotic, Enduracidin, interfering with cell wall synthesis, by using a high-density tilling chip.2009

    • Author(s)
      Rukmana, A., Morimoto, T., Takahashi, H., Giyanto, Ogasawara, N.
    • Journal Title

      Gene Genet Sys 84

      Pages: 253-267

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Noc protein binds to specific DNA sequences to coordinate cell division with chromosome segregation.2009

    • Author(s)
      Wu, L.J., Ishikawa, S., Kawai, Y., Oshima, T., Ogasawara, N., Errington, J.
    • Journal Title

      EMBO J 28

      Pages: 1940-1952

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Systematic genome-wide scanning for genes involved in ATP generation in Escherichia coli.2009

    • Author(s)
      Hara, K.Y., Shimodate, N., Ito, M., Baba, T., Mori, H.
    • Journal Title

      Metab Eng 11

      Pages: 1-7

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential binding profiles of StpA in wild-type and hns mutant cells: a comparative analysis of cooperative partners by ChIP-chip analysis.2009

    • Author(s)
      Uyar, E., Kurokawa, K., Yoshimura, M., Ishikawa, S., Ogasawara, N., Oshima, T.
    • Journal Title

      J Bacteriol 191

      Pages: 2388-2391

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Noc protein binds to specific DNA sequences to coordinate cell division with chromosome segregation2009

    • Author(s)
      Wu, L.J.
    • Journal Title

      EMBO J 28

      Pages: 1940-1952

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Assessment of transcriptional responses of Bacillus subtilis cells to the antibiotic enduracidin, which interferes with cell wall synthesis, using a high-density tiling chip2009

    • Author(s)
      Rukmana, A.
    • Journal Title

      Genes Gent Sys 84

      Pages: 253-267

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential binding profiles of StpA in wild-type and has mutantcells : a comparative analysis of cooperative partners by chromatin immunoprecipitation-microarray analysis2009

    • Author(s)
      Uyar, E.
    • Journal Title

      J Bacteriol 191

      Pages: 2388-2391

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] eSGA: E. coli synthetic genetic array analysis.2008

    • Author(s)
      Butland, G., Babu, M., Diaz-Mejia, J.J., Bohdana, F., Phanse, S., Gold, B., Yang, W., Li, J., Gagarinova, A.G., Pogoutse, O., Mori, H., Wanner, B.L., Lo, H., Wasniewski, J., Christopolous, C., Ali, M., Venn, P., Safavi-Naini, A., Sourour, N., Caron, S., Choi, J.Y., Laigle, L., Nazarians-Armavil, A., Deshpande, A., Joe, S., Datsenko, K.A.,Yamamoto, N., Andrews, B.J., Boone, C., Ding, H., Sheikh, B., Moreno-Hagelseib, G., Greenblatt, J.F., Emili, A.
    • Journal Title

      Nat Methods 5

      Pages: 789-795

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] High-throughput, quantitative analyses of genetic interactions2008

    • Author(s)
      Typas, A., Nichols, R.J., Siegele, D.A., Shales, M., Collins, S.R., Lim, B., Braberg, H., Yamamoto, N., Takeuchi, R., Wanner, B.L., Mori, H., Weissman, J.S., Krogan, N.J., Gross, C.A.
    • Journal Title

      E. coli. Nat Methods 5

      Pages: 781-787

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry2008

    • Author(s)
      Takahashi H, Kai K, Shinbo Y, Tanaka K, Ohta D, Oshima T, Altaf-Ul-Amin M, Kurokawa K, Ogasawara N, Kanaya S.
    • Journal Title

      Anal Bioanal Chem 391

      Pages: 2769-2782

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The functional analysis of YabA, which interacts with DnaA and regulates initiation of chromosome replication in Bacillus subtils.2008

    • Author(s)
      Cho, E., Ogasawara, N., Ishikawa, S.
    • Journal Title

      Gene Genet Sys 83

      Pages: 111-125

    • NAID

      10024395781

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Global regulation by horizontally transferred regulators establishes the pathogenicity of Escherichia coli.2008

    • Author(s)
      Abe, H., Miyahara, A., Oshima, T., Tashiro, K., Ogura, Y., Kuhara, S., Ogasawara, N., Hayashi, T., Tobe, T.
    • Journal Title

      DNA Res 15

      Pages: 25-38

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The functional analysis of YabA, which interacts with DnaA and regulates initiation of chromosome replication in Bacillus subtils2008

    • Author(s)
      Cho, E.
    • Journal Title

      Genes Genet Sys 83

      Pages: 111-125

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry2008

    • Author(s)
      Takahashi, H.
    • Journal Title

      Anal Bioanal Chem 391

      Pages: 2769-2782

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Global regulation by horizontally transferred regulators establishes the pathogenicity of Escherichia coli2008

    • Author(s)
      Abe, H.
    • Journal Title

      DNA Res 15

      Pages: 25-38

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Predicting state transitions in the transcriptome and metabolome using a linear dynamic system model.2007

    • Author(s)
      Morioka, R., Kanaya, S.,, Hirai, M., Yano, M., Ogasawara, N., Saito, K.
    • Journal Title

      BMC Bioinformatics 8,343

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of stable DnaA-binding sites on the Bacillus subtilis genome detected using a modified ChIP-chip method.2007

    • Author(s)
      Ishikawa, S., Ogura, Y., Yoshimura, M., Okumura, H., Cho, E., Kawai, Y., Kurokawa, K., Oshima, T., Ogasawara, N.
    • Journal Title

      DNA Res 14

      Pages: 155-168

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.2007

    • Author(s)
      Loh, P.C., Morimoto, T., Matsuo, Y., Oshima, T., Ogasawara, N.
    • Journal Title

      Gene Genet Sys 82

      Pages: 281-289

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50S ribosomal subunit.2007

    • Author(s)
      Matsuo, Y., Oshima, T., Loh, P.C., Morimoto, T., Ogasawara, N.
    • Journal Title

      J Biol Chem 282

      Pages: 25270-25277

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic simulation of an in vitro multi-enzyme system.2007

    • Author(s)
      Ishii, N., Suga, Y., Hagiya, A., Watanabe, H., Mori, H., Yoshino, M., Tomita, M.
    • Journal Title

      FEBS Lett 581

      Pages: 413-420

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Multiple high-throughput analyses monitor the response of E. coli to perturbations.2007

    • Author(s)
      Ishii, N., Nakahigashi, K., Baba, T., Robert, M., Soga, T., Kanai, A., Hirasawa, T., Naba, M., Hirai, K., Hoque, A., Ho, P.Y., Kakazu, Y., Sugawara, K., Igarashi, S., Harada, S., Masuda, T., Sugiyama, N., Togashi, T., Hasegawa, M., Takai, Y., Yugi, K., Arakawa, K., Iwata, N., Toya, Y., Nakayama, Y., Nishioka, T., Shimizu, K., Mori, H., Tomita, M.
    • Journal Title

      Science 316

      Pages: 593-597

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of the YneS/YgiH and PlsX proteins in phospholipid biosynthesis in both Bacillus subtilis and Escherichia coli.2007

    • Author(s)
      Yoshimura, M., Oshima, T., Ogasawara, N.
    • Journal Title

      BMC Microbiol 7,69

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The entire organization of transcription units on the Bacillus subtilis genome.2007

    • Author(s)
      Kobayashi, H., Akitomi, J., Fujii, N., Kobayashi, K., Altaf-Ul-Amin, M., Kurokawa, K., Ogasawara, N., Kanaya, S.
    • Journal Title

      BMC Genomics 8,197

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The entire organization of transcription units on the Bacillus subtilis genome2007

    • Author(s)
      Kobayashi, H.
    • Journal Title

      BMC Genomics 8

      Pages: 197-197

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of the YneS/YgiH and PlsX proteins in phospholipid biosynthesis in both Bacillus subtilis and Escherichia coli2007

    • Author(s)
      Yoshimura, M
    • Journal Title

      BMC Microbiol 7

      Pages: 69-69

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple high-throughput analyses monitor the response of E. coli to perturbations2007

    • Author(s)
      Ishii, N.
    • Journal Title

      Science 316

      Pages: 593-597

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dynamic simulation of an in vitro multi-enzyme system2007

    • Author(s)
      Ishii, N.
    • Journal Title

      FEBS Lett 581

      Pages: 413-420

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50S ribosomal subunit2007

    • Author(s)
      Matsuo, Y.
    • Journal Title

      J Biol Chem 282

      Pages: 25270-25277

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis2007

    • Author(s)
      Loh, P.C.
    • Journal Title

      Gene Genet Sys 82

      Pages: 281-289

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distribution of stable DnaA-binding sites on the Bacillus subtilis genome detected using a modified ChIP-chip method2007

    • Author(s)
      Ishikawa, S.
    • Journal Title

      DNA Res 14

      Pages: 155-168

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Predicting state transitions in the transcriptome and metabolome using a linear dynamic system model2007

    • Author(s)
      Morioka, R.
    • Journal Title

      BMC Bioinformatics 8

      Pages: 343-343

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA polymerase.2006

    • Author(s)
      Oshima, T., Ishikawa, S., Kurokawa, K., Aiba, H., Ogasawara, N.
    • Journal Title

      DNA Res 13

      Pages: 141-153

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A new FtsZ-interacting protein, YlmF, complements the activity of FtsA during progression of cell division in Bacillus subtilis.2006

    • Author(s)
      Ishikawa, S., Kawai, Y., Hiramatsu, K., Kuwano, M., Ogasawara, N.
    • Journal Title

      Mol Microbiol 60

      Pages: 1364-1380

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bacillus subtilis EzrA and FtsL synergistically regulate FtsZ ring dynamics during cell division.2006

    • Author(s)
      Kawai, Y., Ogasawara, N.
    • Journal Title

      Microbiology 152

      Pages: 1129-1141

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The GTP-binding Protein YlqF Participates in the Late Step of 50 S Ribosomal Subunit Assembly in Bacillus subtilis.2006

    • Author(s)
      Matsuo, Y., Morimoto, T., Kuwano, M., Loh, P.C., Oshima, T., Ogasawara, N.
    • Journal Title

      J Biol Chem 281

      Pages: 8110-8117

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.2006

    • Author(s)
      Baba, T., Ara, T., Hasegawa, M., Takai, Y., Okumura, Y., Baba, M., Datsenko, K.A., Tomita, M., Wanner, B.L., Mori, H.
    • Journal Title

      Mol Sys Biol 2

      Pages: 8-8

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional dissection of YabA, a negative regulator of DNA replication initiation in Bacillus subtilis.2006

    • Author(s)
      Noirot-Gros, M.F., Velten, M., Yoshimura, M., McGovern, S., Morimoto, T., Ehrlich, S.D., Ogasawara, N., Polard, P., Noirot, P.
    • Journal Title

      Proc Natl Acad Sci USA 103

      Pages: 2368-2373

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The GTP-binding protein, YlqF, participates in the late step of 50S ribosomal subunit assembly in Bacillus subtilis2006

    • Author(s)
      Matsuo, Y.
    • Journal Title

      J Biol Chem 281・12

      Pages: 8110-8117

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Bacillus subtilis EzrA and FtsL synergistically regulate FtsZ ring dynamics during cell division2006

    • Author(s)
      Kawai, Y.
    • Journal Title

      Microbiol 152・4

      Pages: 1129-1141

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A new FtsZ-interacting protein, YlmF, complements the activity of FtsA during progression of cell division in Bacillus subtilis2006

    • Author(s)
      Ishikawa, S.
    • Journal Title

      Mol Microbiol 60・6

      Pages: 1364-1380

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA polymerase2006

    • Author(s)
      Oshima, T.
    • Journal Title

      DNA Res 13・4

      Pages: 141-153

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants : the Keio collection2006

    • Author(s)
      Baba, T.
    • Journal Title

      Mol Syst Biol 2

      Pages: 20060008-20060008

    • Related Report
      2006 Annual Research Report
  • [Journal Article] タイリングチップを用いた細菌ゲノム機能研究の可能性2006

    • Author(s)
      大島 拓
    • Journal Title

      細胞工学 25・10

      Pages: 1155-1160

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Functional dissection of YabA, a negative regulator of DNA replication initiation in Bacillus subtilis2006

    • Author(s)
      Noirot-Gros, M.
    • Journal Title

      Proc Natl Acad Sci USA 103

      Pages: 2368-2373

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The GTP-binding protein, YlqF, participates in the late step of 50S ribosomal subunit assembly in Bacillus subtilis2006

    • Author(s)
      Matsuo, Y.
    • Journal Title

      J Biol Chem (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Bacillus subtilis EzrA and FtsL synergistically regulate FtsZ ring dynamics during cell division2006

    • Author(s)
      Kawai, Y.
    • Journal Title

      Microbiol (in press)

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems2005

    • Author(s)
      Bongiorni, C
    • Journal Title

      J Bacteriol 187

      Pages: 4353-4361

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Bacillus subtilis YabA is involved in determining the timing and synchrony of replication initiation2005

    • Author(s)
      Hayashi, M.
    • Journal Title

      FEMS Microbiol Lett 247

      Pages: 73-79

    • Related Report
      2005 Annual Research Report
  • [Presentation] 大腸菌O157:H7 sakaiおよびK12株のFur結合プロファイルのChIP-chip解析による比較2010

    • Author(s)
      大島拓
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2010-03-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 大腸菌核様体タンパク質LRPとH-NS間の協同的な働き2010

    • Author(s)
      上田剛士
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2010-03-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] ChIP-qPCR法による大腸菌K-12の銅耐性機構の解析2009

    • Author(s)
      草合千嘉子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] ChAP-chip解析を用いたin vivoにおける枯草菌RNA polymerase α subunit(RoA)と相互作用するゲノム部位の網羅解析2009

    • Author(s)
      村山智彦
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] ChIP-chip解析による異なる大腸菌種におけるFurの結合領域の比較解析2009

    • Author(s)
      加賀山陽子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] FtsZのアクセサリー蛋白質と核様体閉鎖によるZ-ring形成の制御2009

    • Author(s)
      石川周
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Search of nucleoid proteins in Bacillus subtilis : comparative analysis using ChAP(ChIP)-chip analysis between in B.subtilis and E.coli.2009

    • Author(s)
      大島拓
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 枯草菌における新規核様体蛋白質の同定2009

    • Author(s)
      Ying Lei
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 枯草菌の細胞分裂におけるFtsZ複合体のメカニズム解明2009

    • Author(s)
      調真里子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] The initiation complex of Bacillus subtilis RNA polymerase is rapidly converted to the elongation complex in vivo2009

    • Author(s)
      Ishikawa, S.
    • Organizer
      5th Internatinal Conference on Gram-positive Microorizamsms
    • Place of Presentation
      San Diego, CA USA
    • Year and Date
      2009-06-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] Involvement of DnaA in the organization of B.subtilis nucleoid structure2009

    • Author(s)
      Okumura, H.
    • Organizer
      5th Internatinal Conference on Gram-positive Microorganisms
    • Place of Presentation
      San Diego, CA USA
    • Year and Date
      2009-06-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] 細菌の細胞分裂の分子メカニズム2009

    • Author(s)
      石川周
    • Organizer
      日本農芸化学会2009年度大会
    • Place of Presentation
      福岡
    • Year and Date
      2009-03-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] ChIP-chip法による大腸菌・枯草菌の核様体タンパク質の研究2009

    • Author(s)
      小笠原直毅
    • Organizer
      第3回日本ゲノム微生物学会年会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 枯草菌染色体のDnaA結合配列の機能2009

    • Author(s)
      奥村元
    • Organizer
      第3回日本ゲノム微生物学会年会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] Control of RNA polymerase dynamics by GreA in B. subtilis2009

    • Author(s)
      楠屋陽子
    • Organizer
      第3回日本ゲノム微生物学会年会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Gene-to gene and gene-to-metabolite network analysis based on the time lag between gene and metabolite in Escherichia coli.2009

    • Author(s)
      Takahashi, H., Morikawa, R., Kai, K., Ohta, D., Oshima, T., Altaf-Ul-Amin, M., Ogasawara, N., Kanaya, S.
    • Organizer
      4th European Conference on Prokaryotic Genomics
    • Place of Presentation
      Gottingen, Germany
    • Related Report
      2009 Final Research Report
  • [Presentation] Involvement of DnaA in the organization of B. subtilis nucleoid structure.2009

    • Author(s)
      Okumura, H., Yoshimura, M., Ishikawa, S., Ogasawara, N.
    • Organizer
      15th International Conference on Bacilli (5th International Conference on Gram-positive Microorganisms)
    • Place of Presentation
      San Diego, CA USA
    • Related Report
      2009 Final Research Report
  • [Presentation] Distribution of stable DnaA binding sites on the Bacillus subtilis genome2008

    • Author(s)
      Okumura, H.
    • Organizer
      XX International Congress of Genetics
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-07-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] Distribution of RNA polymerase on the Bacillus subtilis genome2008

    • Author(s)
      Kusuya, Y.
    • Organizer
      XX International Congress of Genetics
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-07-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] Distribution of StpA across the E. coli genome and functionalrelationship with H-NS2008

    • Author(s)
      Uya, E.
    • Organizer
      XX International Congress of Genetics
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-07-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] A novel regulation mechanism for the initiation of replication in Bacillus subtilis2008

    • Author(s)
      Cho, E.
    • Organizer
      EMBO Conference on Replication and Segregation of Chromosomes
    • Place of Presentation
      Geilo, Norway
    • Year and Date
      2008-06-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Distribution of RNA polymerase on the Bacillus subtilis genome2008

    • Author(s)
      Ogasawara, N.
    • Organizer
      GENOMES 2008, Furictional Genomics of Microorganisms
    • Place of Presentation
      Paris, France
    • Year and Date
      2008-04-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Distribution of StpA across the E. coli genome and functional relationship with H-NS.2008

    • Author(s)
      Uya, E., Oshima, T., Ogasawara, N.
    • Organizer
      XX International Congress of Genetics
    • Place of Presentation
      Berlin, Germany
    • Related Report
      2009 Final Research Report
  • [Presentation] A novel regulation mechanism for the initiation of replication in Bacillus subtilis.2008

    • Author(s)
      Cho, E., Ishikawa, S., Ogasawara, N.
    • Organizer
      EMBO Conference on Replication and Segregation of Chromosomes
    • Place of Presentation
      Geilo, Norway
    • Related Report
      2009 Final Research Report
  • [Presentation] Distribution of RNA polymerase on the Bacillus subtilis genome.2008

    • Author(s)
      Kusuya, Y., Oshima, T., Ishikawa, S., Kurokawa, K., Ogasawara, N.
    • Organizer
      Functional Genomics of Microorganisms
    • Place of Presentation
      Paris, France
    • Related Report
      2009 Final Research Report
  • [Presentation] 枯草菌の50Sリボソームサブユニットの生合成におけるGTP結合タンパク質の結合モデルの提案2008

    • Author(s)
      松尾 芳隆
    • Organizer
      第2回日本ゲノム微生物学会年会
    • Place of Presentation
      大阪
    • Related Report
      2007 Annual Research Report
  • [Presentation] Distribution of StpA across the E. coli genome and its functional relationship with H-NS2008

    • Author(s)
      EBRU UYAR
    • Organizer
      第2回日本ゲノム微生物学会年会
    • Place of Presentation
      大阪
    • Related Report
      2007 Annual Research Report
  • [Presentation] 転写伸長因子NusAとGreAの枯草菌ゲノム上での分布2008

    • Author(s)
      楠屋 陽子
    • Organizer
      第2回日本ゲノム微生物学会年会
    • Place of Presentation
      大阪
    • Related Report
      2007 Annual Research Report
  • [Presentation] 枯草菌染色体のDnaA結合配列の機能2008

    • Author(s)
      奥村 元
    • Organizer
      第2回日本ゲノム微生物学会年会
    • Place of Presentation
      大阪
    • Related Report
      2007 Annual Research Report
  • [Presentation] Distribution of RNA polymerase on the Bacillus subtilis genome2008

    • Author(s)
      Ogasawara, N.
    • Organizer
      Functional Genomics of Microorganisms
    • Place of Presentation
      Paris, France
    • Related Report
      2007 Annual Research Report
  • [Presentation] N-terminal deletion mutant of YlqF, which is essential GTP-binding protein, displays dominant negative phenotype in Bacillus subtilis.2007

    • Author(s)
      Matsuo, Y., Loh, P.C., Morimoto, T., Oshima, T., Ogasawara, N.
    • Organizer
      14th International Conference on Bacilli
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2009 Final Research Report
  • [Presentation] Regulation of initiation of replication of the Bacillus subtilis genome by DnaA and YabA2007

    • Author(s)
      Cho, E.
    • Organizer
      14th Conference on Functional Genomics of Gram-Positive Microorganisms
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] Distribution of stable DnaA binding sites on the Bacillus subtilis genome revealed by a modified ChIP-chip method2007

    • Author(s)
      Okumura, H.
    • Organizer
      14th Conference on Functional Genomics of Gram-Positive Microorganisms
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] N-terminal deletion mutant of YlqF, which is essential GTP-binding protein, displays dominant negative phenotype in Bacillus subtilis2007

    • Author(s)
      Matsuo, Y.
    • Organizer
      14th Conference on Functional Genomics of Gram-Positive Microorganisms
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] The GTP-binding protein YqeH is essential for the biogenesis of 30S ribosome subunit in Bacillus subtilis2007

    • Author(s)
      Loh, P. C.
    • Organizer
      14th Conference on Functional Genomics of Gram-Positive Microorganisms
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] Distribution of Transcription Elongation Factor NusA and GreA in Bacillus subtilis2007

    • Author(s)
      Kusuya, Y.
    • Organizer
      14th Conference on Functional Genomics of Gram-Positive Microorganisms
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] In vivo dynamics of the Bacillus subtilis RNA polymerase on the genome2007

    • Author(s)
      Ishikawa, S.
    • Organizer
      14th Conference on Functional Genomics of Gram-Positive Microorganisms
    • Place of Presentation
      Pisa, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] 枯草菌の細胞システムのゲノムからの理解2007

    • Author(s)
      小笠原 直毅
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 枯草菌の細胞分裂初期にFtsZに直接結合するFtsA、YlmFの分子機能の解析2007

    • Author(s)
      大藤 仁夢
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 大腸菌核様体タンパクLhpのChIP-chip解析2007

    • Author(s)
      中川 隆生
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 大腸菌核様体タンパク質H-NSの高浸透圧下でのゲノムへの分布と遺伝子発現制御機構の解析2007

    • Author(s)
      上田 剛士
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 枯草菌のリン酸飢餓時に発現するグローバル調節因子PhoPの標的部位の網羅的解析2007

    • Author(s)
      川岸 敏也
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] The GTP-binding protein YqeH participates in the biogenesis of 30S ribosome subunit in Bacillus subtilis.2006

    • Author(s)
      Loh, P.C., Morimoto, T., Matsuo, Y., Ogasawara, N.
    • Organizer
      Translational Control
    • Place of Presentation
      Cold Spring Harbor, NY USA
    • Related Report
      2009 Final Research Report
  • [Book] 枯草菌でシステム生物学(吉川寛、堀寛編, 研究を支えるモデル生物)2009

    • Author(s)
      小笠原直毅
    • Publisher
      化学同人
    • Related Report
      2009 Final Research Report
  • [Book] 大腸菌でシステム生物学(吉川寛、堀寛編, 研究を支えるモデル生物)2009

    • Author(s)
      森浩禎
    • Publisher
      化学同人
    • Related Report
      2009 Final Research Report
  • [Book] 蛋白質核酸酵素(細菌の細胞分裂の分子メカニズム, 53)2008

    • Author(s)
      石川周、小笠原直毅
    • Publisher
      共立出版
    • Related Report
      2009 Final Research Report
  • [Book] 細胞工学(タイリングチップを用いた細菌ゲノム機能研究の可能性, 25)2006

    • Author(s)
      大島拓、石川周、黒川顕、小笠原直毅
    • Publisher
      秀潤社
    • Related Report
      2009 Final Research Report

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Published: 2005-04-01   Modified: 2018-03-28  

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