| Budget Amount *help |
¥69,600,000 (Direct Cost: ¥69,600,000)
Fiscal Year 2009: ¥13,500,000 (Direct Cost: ¥13,500,000)
Fiscal Year 2008: ¥13,500,000 (Direct Cost: ¥13,500,000)
Fiscal Year 2007: ¥13,800,000 (Direct Cost: ¥13,800,000)
Fiscal Year 2006: ¥13,800,000 (Direct Cost: ¥13,800,000)
Fiscal Year 2005: ¥15,000,000 (Direct Cost: ¥15,000,000)
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| Research Abstract |
We have accumulated a large amount of knowledge concerning with molecular biology by comparing biological sequences, such as DNA, RNA and amino acid sequences. On the other hand, rapid progress of sequencing technology have brought accumulation of a large amount of sequence data. Then, its quantity is now exceeding the upper limit of application of existing sequence comparison methods. Here, we have developed methods which are capable of comparing such a large amount of sequence data with high accuracy, and have tackled the challenge to biological knowledge discovery by applying the methods. As a result, we have revealed molecular mechanism of transcriptional regulation of microRNA function.
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