| Budget Amount *help |
¥156,700,000 (Direct Cost: ¥156,700,000)
Fiscal Year 2009: ¥30,200,000 (Direct Cost: ¥30,200,000)
Fiscal Year 2008: ¥30,200,000 (Direct Cost: ¥30,200,000)
Fiscal Year 2007: ¥32,100,000 (Direct Cost: ¥32,100,000)
Fiscal Year 2006: ¥32,400,000 (Direct Cost: ¥32,400,000)
Fiscal Year 2005: ¥31,800,000 (Direct Cost: ¥31,800,000)
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| Research Abstract |
In order to identify susceptible gene for multi-factorial disease such as common disease, we have developed two methods, GWAS (genome-wide association study) using 30,000 microsatellites and detection of linkage between a trait and a marker in a random mating population without pedigree record. Utilizing these new methods, we could identify more than 30 disease susceptible genes. Towards genome-based drug discovery based on these disease genes, we have developed in silico network analysis and new yeast two hybrid system.
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