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Study of the microbial system based on high-throughput DNA sequencing

Research Project

Project/Area Number 17020007
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe University of Tokyo (2007-2009)
Kitasato University (2005-2006)

Principal Investigator

HATTORI Masahira  The University of Tokyo, 大学院・新領域創成科学研究科, 教授 (70175537)

Co-Investigator(Kenkyū-buntansha) YAMASHITA Atsushi  北里大学, 北里生命科学研究所, 助手 (20348585)
TOH Hidehiro  理化学研究所, 基幹研究所, 研究員 (10353468)
TAKAMI Hideto  海洋研究開発機構, 極限環境生物圏研究センター, グループリーダー (70359165)
Project Period (FY) 2005 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥516,300,000 (Direct Cost: ¥516,300,000)
Fiscal Year 2009: ¥103,800,000 (Direct Cost: ¥103,800,000)
Fiscal Year 2008: ¥103,100,000 (Direct Cost: ¥103,100,000)
Fiscal Year 2007: ¥103,100,000 (Direct Cost: ¥103,100,000)
Fiscal Year 2006: ¥103,100,000 (Direct Cost: ¥103,100,000)
Fiscal Year 2005: ¥103,200,000 (Direct Cost: ¥103,200,000)
Keywordsゲノム / メタゲノム / 微生物 / 腸内細菌 / 細菌 / 細菌叢 / 遺伝子 / 塩基配列 / DNA
Research Abstract

In this study, we established a new research infrastructure for the analysis of the biological system of bacteria by using high-throughput DNA sequencing technologies. Particularly, we focused on the genome analysis of human microbes such as E. coli, Bifidobacteria and Lactobacillus species, and also established a culture-independent metagenomic approach by which the biological function of human gut microbiota was clarified by comprehensively identifying genes encoded by the gut microbiota including unculturable species.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (105 results)

All 2010 2009 2008 2007 2006 2005 Other

All Journal Article (45 results) (of which Peer Reviewed: 34 results) Presentation (54 results) Book (4 results) Remarks (2 results)

  • [Journal Article] Complete genome sequence of the wild-type commensal Escherichia coli strain SE15 belonging to phylogenetic group B22010

    • Author(s)
      藤、服部, 他(全14名, 1, 14番目)
    • Journal Title

      J. Bacteriol. 192

      Pages: 1165-1166

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Complete genome sequence of the wild-type commensal Escherichia coli strain SE15 belonging to phylogenetic group B22010

    • Author(s)
      Toh H, 他
    • Journal Title

      J.Bacteriol 192

      Pages: 1165-1166

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete genome sequence of probiotic Lactobacillus rhamnosus ATCC531032009

    • Author(s)
      藤、服部, 他(全7名, 2, 7番目)
    • Journal Title

      J. Bacteriol. 191

      Pages: 7630-7631

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The human intestinal microbiome: A new frontier of human biology2009

    • Author(s)
      服部, Taylor TD
    • Journal Title

      DNA Res. 16

      Pages: 1-12

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Complete genome sequence of probiotic Lactobacillus rhamnosus ATCC 531032009

    • Author(s)
      Morita H, 他
    • Journal Title

      J.Bacteriol 191

      Pages: 7630-7631

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The identification and functional implications of human-specific "fixed" amino acid substitutions in the glutamate receptor family2009

    • Author(s)
      Goto H, 他
    • Journal Title

      BMC Evol.Biol. 9

      Pages: 224-224

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Microbial populations responding to denitrification-inductive conditions in rice paddy soil, as revealed by comparative 16S rRNA gene analysis2009

    • Author(s)
      Ishii S, 他
    • Journal Title

      Appl.Environ.Microbiol. 75

      Pages: 7070-7078

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content2009

    • Author(s)
      Maruyama F, 他
    • Journal Title

      BMC Genomics 10

      Pages: 358-358

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative genomics revealed the mechanism of parallel evolution of enterohemorrhagic Escherichia coli2009

    • Author(s)
      Ogura Y, 他
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 17939-17944

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome sequence of the lager brewing yeast, an interspecies hybrid2009

    • Author(s)
      Nakao Y, 他
    • Journal Title

      DNA Res. 16

      Pages: 115-129

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CDld-dependent regulation of bacterial colonization in the intestine of mice2009

    • Author(s)
      Nieuwenhuis E, 他
    • Journal Title

      J.Clin.Invest. 119

      Pages: 1241-1250

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 次世代シークエンサーの現状と展望2009

    • Author(s)
      服部正平
    • Journal Title

      Cancer Frontier 11

      Pages: 121-130

    • Related Report
      2009 Annual Research Report
  • [Journal Article] メタゲノミクスとヒト腸内細菌叢の機能2009

    • Author(s)
      服部正平
    • Journal Title

      実験医学 27

      Pages: 121-127

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 腸内細菌叢のメタゲノム解析とヒト生物学への展開2009

    • Author(s)
      服部正平
    • Journal Title

      感染・炎症・免疫 39

      Pages: 2-13

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SE11 isolated from a healthy adult2008

    • Author(s)
      藤、服部, 他(全12名, 2, 12番目)
    • Journal Title

      DNA Res. 15

      Pages: 375-386

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genome of an endosymbiont coupling N2 fixation to cellulolysis within protist cells in termite gut2008

    • Author(s)
      本郷、服部, 他(全11名, 5, 10番目)
    • Journal Title

      Science 322

      Pages: 1108-1109

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.2008

    • Author(s)
      大西、服部, 他(全9名, 8番目)
    • Journal Title

      J. Bacteriol. 190

      Pages: 4050-4060

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Complete genome of the uncultured 'Termite Group 1' bacteria in a single host protist cell2008

    • Author(s)
      Hongoh, Y, 他
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages: 5555-5560

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the antimicrobial peptide attacin loci from Glossinc morsitans2008

    • Author(s)
      Wang, J, 他
    • Journal Title

      Insect Mol. Biol 17

      Pages: 293-302

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BAC library construction and BAC end sequencing of five Drosophila species : the comparative map with the D. melanogaster genome2008

    • Author(s)
      Murakami, K, 他
    • Journal Title

      Genes Genet Syst 83

      Pages: 245-256

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production2008

    • Author(s)
      Morita, H, 他
    • Journal Title

      DNA Res 15

      Pages: 151-161

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cloning and characterization of mevalonate pathway genes in natural rubber producina plant. Hevea brasiliensis2008

    • Author(s)
      Sando, T, 他
    • Journal Title

      Biosci. Biotechnol. Biochem 72

      Pages: 2049-2060

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome sequence determination of Porphyromonas gingivalis strain ATCC 33277 and genomic comparison with strain W83 revealed extensive genome rearrangements in P. gingivalis2008

    • Author(s)
      Naito, M, 他
    • Journal Title

      DNA Res 15

      Pages: 215-225

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The whole-genome sequencing of Orientia tsutsugarnushi revealed an explosive gene amplification with the reductive genome evolution in an obligate intracellular bacterium2008

    • Author(s)
      Nakayama, K, 他
    • Journal Title

      DNA Res 15

      Pages: 185-199

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Systematic identification and sequence analysis of the genomic islands of the enteropathogenic Escherichia coli strain B171-8 by the combined use of whole genome PCR scanning and fosmid mapping2008

    • Author(s)
      Ogura, Y, 他
    • Journal Title

      J. Bacteriol. 190

      Pages: 6948-6960

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genome of an endosymbiont coupling N_2 fixation to cellulolysis withinprotist cells in termite gut2008

    • Author(s)
      Hongoh, Y, 他
    • Journal Title

      Science 322

      Pages: 1108-1109

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Large-scale microfabricated channel plates for high-throughput, fully automa'ted DNA sequencing2008

    • Author(s)
      Kumagai, H, 他
    • Journal Title

      Electrophoresis 29

      Pages: 4723-4732

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cloning and characterization of the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway genes of a natural-rubber producing plant, Hevea brasiliensis2008

    • Author(s)
      Sando, T, 他
    • Journal Title

      Biosci Biotechnol Biochem 72

      Pages: 2903-2917

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete genome sequence and comparative analysis of the wild-type commensal Escherichia coli strain SEll isolated from a healthy adult2008

    • Author(s)
      Oshima, K, 他
    • Journal Title

      DNA Res 15

      Pages: 375-386

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The human intestinal microbiome : A new frontier of human biology2008

    • Author(s)
      Hattori M and Taylor TD
    • Journal Title

      DNA Res 16

      Pages: 1-12

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete Genome Sequence of Finegoldia magna, an Anaerobic Opportu nistic Pathogen2008

    • Author(s)
      Goto T, 他
    • Journal Title

      DNA Research 15

      Pages: 39-47

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes.2007

    • Author(s)
      黒川、藤、高見、服部, 他(全20名, 5, 7, 20番目)
    • Journal Title

      DNA Res. 14

      Pages: 169-181

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] An improved isolation method for metagenomic analysis of the microbial flora of the human intestine2007

    • Author(s)
      森田、高見、服部, 他(全8名, 6, 8番目)
    • Journal Title

      Microbes Environ. 22

      Pages: 214-222

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Complete nucleotide sequence of pLD-TEX-KL, a 66-kb plasmid of Legionella dumoffii TEX-KL strain2007

    • Author(s)
      Qin T, 他
    • Journal Title

      Plasmid 58

      Pages: 261-268

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes2007

    • Author(s)
      Kurokawa K, 他
    • Journal Title

      DNA Research 14

      Pages: 169-181

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The 160-kilobase genome of the bacterial endosymbiont Carsonella2006

    • Author(s)
      中鉢、藤、服部, 他(全7名, 3, 7番目)
    • Journal Title

      Science 314

      Pages: 267-267

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Massive genome erosion and functional adaptations provide insights into the commensalistic lifestyle of the tsetse endosymbiont, Sodalis glossinidius2006

    • Author(s)
      藤、山下、服部, 他(全7名, 1, 4, 6番目)
    • Journal Title

      Genome Res. 16

      Pages: 149-156

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficient and stable transformation of Lactuca sativa L. cv. Cisco (lettuce) Plastids2006

    • Author(s)
      Kanamoto H他
    • Journal Title

      Transgenic Res. 15・2

      Pages: 205-217

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The 160-kilobase genome of the bacterial endosymbiont Carsonella2006

    • Author(s)
      Nakabachi A他
    • Journal Title

      Science 314・5797

      Pages: 267-267

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A large-scale full-length cDNA analysis to explore the budding yeast transcriptome2006

    • Author(s)
      Miura F 他
    • Journal Title

      Proc Natl. Acad. Sci. USA 103・47

      Pages: 17846-17851

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Massive genome erosion and functional adaptations provide insights into the commensalistic lifestyle of the tsetse endosymbiont, Sodalis glossinidius2006

    • Author(s)
      Toh H他
    • Journal Title

      Genome Research 16・2

      Pages: 149-156

    • Related Report
      2005 Annual Research Report
  • [Journal Article] A rapid and simple transcriptional sequencing method for GC-rich DNA regions2006

    • Author(s)
      Izawa M他
    • Journal Title

      Jpn J Vet Res 53・3-4

      Pages: 159-168

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection2005

    • Author(s)
      Kuroda M他
    • Journal Title

      Proc Natl.Acad.Sci.USA 102・37

      Pages: 13272-13277

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The genome sequence of Clostridium botulinum type C neurotoxin-converting phage and the molecular mechanisms of unstable lysogeny2005

    • Author(s)
      Sakaguchi Y他
    • Journal Title

      Proc Natl.Acad.Sci.USA 102・48

      Pages: 17472-17477

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Identification of large ancient duplications associated with human gene deserts2005

    • Author(s)
      Itoh T他
    • Journal Title

      Nature Genetics 37・10

      Pages: 1041-1043

    • Related Report
      2005 Annual Research Report
  • [Presentation] High-throughput analysis of human gut microbiomes by next generation sequencing2010

    • Author(s)
      服部
    • Organizer
      第83回日本細菌学会: International Symposium‘Microbiota and Intestinal Homeostasis'
    • Place of Presentation
      横浜
    • Year and Date
      2010-03-29
    • Related Report
      2009 Final Research Report
  • [Presentation] High-throughput analysis of human gut microbiomes by next generation sequencing2010

    • Author(s)
      Hattori M
    • Organizer
      第83回細菌学会 国際シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 次世代シークエンサーを用いた微生物ゲノムと細菌叢メタゲノム研究2010

    • Author(s)
      Oshima K, 他
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metagenomics-based 16S ribosomal RNA gene profiling-A new strategy for the taxonomic analysis of human gut microbiota with high quantification-2010

    • Author(s)
      Kim S-W, 他
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] P1様バクテリアに支持される微生物マットのメタゲノム解析2010

    • Author(s)
      Takami H, 他
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] ピロリ菌10株のゲノム比較によるゲノム再編の検出2010

    • Author(s)
      Kawai M, 他
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 吸血衛生害虫トコジラミにおける菌細胞必須栄養共生細菌ボルバキアの発見およびゲノム解析2010

    • Author(s)
      Fukatsu T, 他
    • Organizer
      第4回日本ゲノム微生物学会年会
    • Place of Presentation
      九州大学
    • Related Report
      2009 Annual Research Report
  • [Presentation] 超高速シークエンス時代の環境微生物研究2009

    • Author(s)
      Hattori M
    • Organizer
      バイオエンジニアリング(JBA)研究会講演会
    • Place of Presentation
      東京 JBA
    • Year and Date
      2009-12-04
    • Related Report
      2009 Annual Research Report
  • [Presentation] メタゲノム科学:微生物研究の新たなフロンティア2009

    • Author(s)
      Hattori M
    • Organizer
      かわさきサイエンス&テクノロジーフォーラム2009
    • Place of Presentation
      かながわサイエンスパーク
    • Year and Date
      2009-11-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metagenomics: a gene-centric approach for the human gut microbiome research2009

    • Author(s)
      服部
    • Organizer
      2009 symposium on the metabolism of foods and drugs by intestinal microflora
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-10-20
    • Related Report
      2009 Final Research Report
  • [Presentation] Metagenomics : a gene-centric approach for the human gut microbiome research2009

    • Author(s)
      Hattori M
    • Organizer
      2009 symposium on the metabolism of foods and drugs by intestinal mycroflora
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-10-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional profiling of the human gut microbiome by metagenomics2009

    • Author(s)
      Hattori M
    • Organizer
      MARCO Symposium Satellite Workshop
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2009-10-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト腸内細菌叢のメタゲノム・ゲノム解析2009

    • Author(s)
      Hattori M
    • Organizer
      日本遺伝学会第81回大会
    • Place of Presentation
      信州大学
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト腸内細菌叢の高速ゲノム解析2009

    • Author(s)
      Hattori M
    • Organizer
      第26回和漢医薬学会学術大会
    • Place of Presentation
      千葉 幕張メッセ
    • Year and Date
      2009-08-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] 環境細菌叢のメタゲノム解析2009

    • Author(s)
      Hattori M
    • Organizer
      水産総合研究センターシンポジウム
    • Place of Presentation
      東京 発明会館
    • Year and Date
      2009-08-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metagenomics of the Human Gut Microbiome : A New Frontier of Human Biology2009

    • Author(s)
      Hattori M
    • Organizer
      The 2nd RIKEN-University of Edinburgh Joint Workshop for Computational and Systems Biology
    • Place of Presentation
      英国大使館
    • Year and Date
      2009-05-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Gene-centric metagenomics decoding the human intestinal microbiome2009

    • Author(s)
      Hattori, M.
    • Organizer
      The 2nd Sympojium on the MEXT Priority research for Immunological Self -Recognition and its Dsi orders
    • Place of Presentation
      京都大学
    • Year and Date
      2009-02-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] 腸内細菌のメタゲノミクス2009

    • Author(s)
      服部正平
    • Organizer
      国立遺伝学研究所研究会
    • Place of Presentation
      国立遺伝学研究所
    • Year and Date
      2009-01-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] 次世代シークエンサーを用いた微生物ゲノムとヒト腸内細菌叢メタゲノム研究2009

    • Author(s)
      Oshima K, 他
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metagenomics-based 16S ribosomal RNA gene profiling2009

    • Author(s)
      Kim S-W, 他
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2009 Annual Research Report
  • [Presentation] Assessment of microbial DNA extraction methods for metagenomics2009

    • Author(s)
      Kikuchi M, 他
    • Organizer
      The 8^<th> Advance Genomics Workshop
    • Place of Presentation
      国立情報学研究所
    • Related Report
      2009 Annual Research Report
  • [Presentation] Multiple omics identified microbial metabolites to protect host from enterohemorrhagic Escherichia coli O157:H7 lethal infection2009

    • Author(s)
      Fukuda S, 他
    • Organizer
      The 8^<th> Advance Genomics Workshop
    • Place of Presentation
      国立情報学研究所
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metagenomics and genomics decoding human intestinal microbiomes2009

    • Author(s)
      Kim S-W, 他
    • Organizer
      The 8^<th> Advance Genomics Workshop
    • Place of Presentation
      国立情報学研究所
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metagenomics and genomics decoding human intestinal microbiomes2009

    • Author(s)
      Kim S-W, 他
    • Organizer
      The Biology of Genomes
    • Place of Presentation
      Cold Spring Harbor 研究所(米国ニューヨーク)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 微生物ゲノム解析の支援と共同、独自研究の現状2009

    • Author(s)
      大島健志朗, 他
    • Organizer
      第3回日本ゲノム微生物学会大会
    • Place of Presentation
      中央大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] A large-scale analysis of 16S ribosomal gene sequences in the human intestinal microbiota2009

    • Author(s)
      金錫元, 他
    • Organizer
      第3回日本ゲノム微生物学会大会
    • Place of Presentation
      中央大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] 腸内細菌叢のメタゲノム解析における細菌DNA抽出法の確立2009

    • Author(s)
      上野真理子, 他
    • Organizer
      第3回日本ゲノム微生物学会大会
    • Place of Presentation
      中央大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト内部環境マイクロバイオームのメタゲノム解析2008

    • Author(s)
      服部正平
    • Organizer
      農業環境技術研究所公開セミナー
    • Place of Presentation
      エポカルつくば
    • Year and Date
      2008-12-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] メタゲノム解析 : 腸内細菌研究の新たな展開2008

    • Author(s)
      服部正平
    • Organizer
      第46回小腸研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト内部環境マイクロバイオームのメタゲノミクス2008

    • Author(s)
      服部正平
    • Organizer
      第5回コンビナトリアル・バイオエンジニアリング会議
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 次世代型超高速シークエンサーの展望とヒトマイクロバイオーム解析2008

    • Author(s)
      服部正平
    • Organizer
      日本人類遺伝学会(第53回大会)
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-09-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] Metagenomics of the human gut microbiome2008

    • Author(s)
      Hattori, M.
    • Organizer
      The 8th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      兵庫県淡路島
    • Year and Date
      2008-09-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト腸内常在菌のゲノム及びメタゲノム解析2008

    • Author(s)
      服部正平
    • Organizer
      日本進化学会第10回東京大会
    • Place of Presentation
      東京大学
    • Year and Date
      2008-08-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト腸内細菌叢の大規模シークエンス解析2008

    • Author(s)
      服部正平
    • Organizer
      バイオインダストリー協会発酵と代謝研究会シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2008-07-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト腸内細菌叢のメタゲノム解析-健康未来科学をめざして2008

    • Author(s)
      服部正平
    • Organizer
      日本化学療法学会総会(第56回)
    • Place of Presentation
      岡山大学
    • Year and Date
      2008-06-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヒト腸内細菌叢の大規模ゲノム解析2008

    • Author(s)
      服部正平
    • Organizer
      日本農芸化学会2008年度大会
    • Place of Presentation
      名城大学
    • Year and Date
      2008-03-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] A large-scale analysis of 16S ribosomal RNA gene profiling for the human gut microbiota2008

    • Author(s)
      金 錫元, 他
    • Organizer
      第2回日本ゲノム微生物学会大会
    • Place of Presentation
      大阪大学
    • Year and Date
      2008-03-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒト腸内常在大腸菌のゲノム解析2008

    • Author(s)
      藤 英博, 他
    • Organizer
      第2回日本ゲノム微生物学会大会
    • Place of Presentation
      大阪大学
    • Year and Date
      2008-03-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] 微生物ゲノムシークエンシングプロジェクト2008

    • Author(s)
      大島 健志朗, 他
    • Organizer
      第2回日本ゲノム微生物学会大会
    • Place of Presentation
      大阪大学
    • Year and Date
      2008-03-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超高速シークエンスと腸内細菌叢メタゲノム解析2008

    • Author(s)
      服部正平
    • Organizer
      第2回神戸統合医療研究会合同講演会
    • Place of Presentation
      神戸大学
    • Year and Date
      2008-02-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Metagenomic analysis of the human gut microbiota: A new frontier of human biology2008

    • Author(s)
      服部
    • Organizer
      JSPS-DST Asian Academic Seminar 2008
    • Place of Presentation
      インドバンガロール
    • Related Report
      2009 Final Research Report
  • [Presentation] Comparative metagenomics revealed commonly enriched gene sets in human intestine2008

    • Author(s)
      黒川顕, 他
    • Organizer
      The Biology of Genomes
    • Place of Presentation
      Cold Spring Harbor Labor atoly(米国)
    • Related Report
      2008 Annual Research Report
  • [Presentation] Metagenomics of the human gut microbiota : A new frontier of human biology2008

    • Author(s)
      Hattori, M.
    • Organizer
      Function of Intestinal Microbiota and Food (FIMF) Forum 2008
    • Place of Presentation
      東京大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] Metagenomic analysis of the human gut microbiota : A new frontier of human biology2008

    • Author(s)
      Hattori, M.
    • Organizer
      JSPS-DST Asian Academic Seminar 2008
    • Place of Presentation
      インド・Bangalore
    • Related Report
      2008 Annual Research Report
  • [Presentation] メタゲノム解析から見えてきたヒト腸内細菌叢の機能2008

    • Author(s)
      服部正平
    • Organizer
      第17回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      九州大学
    • Related Report
      2008 Annual Research Report
  • [Presentation] High-throughput sequencing of the human gut microbiome2008

    • Author(s)
      服部正平, 大島健志朗
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会一合同大会
    • Place of Presentation
      神戸ポートピアホテル
    • Related Report
      2008 Annual Research Report
  • [Presentation] A Large-scale analysis of 16S ribosomal RNA gene profiling for the human gut microbiota2008

    • Author(s)
      金錫元, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会一合同大会
    • Place of Presentation
      神戸ポートピアホテル
    • Related Report
      2008 Annual Research Report
  • [Presentation] プロバイオティクス乳酸菌Lactobacillus rhamnosusのゲノム解析2008

    • Author(s)
      藤英博, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会一合同大会
    • Place of Presentation
      神戸ポートピアホテル
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超高速シークエンサーを用いたゲノム(メタゲノム)解析2008

    • Author(s)
      大島健志朗, 他
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会一合同大会
    • Place of Presentation
      神戸ポートピアホテル
    • Related Report
      2008 Annual Research Report
  • [Presentation] Sequencing of human gut microbiomes2007

    • Author(s)
      Hattori M
    • Organizer
      The 7th Advance Genomics Workshop
    • Place of Presentation
      東京フォーラム
    • Year and Date
      2007-11-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヒト腸内細菌叢ゲノムのシークエンシング2007

    • Author(s)
      服部正平
    • Organizer
      第23回日本微生物生態学会松山大会
    • Place of Presentation
      愛媛大学
    • Year and Date
      2007-09-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] Sequencing of bacterial genomes and metagenomes2007

    • Author(s)
      Hattori M
    • Organizer
      Metagenomics 2007
    • Place of Presentation
      米国カルフォルニア大学サンディエゴ校
    • Year and Date
      2007-07-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] Sequencing of human gut microbiomes2007

    • Author(s)
      服部
    • Organizer
      The 7th Advance Genomics Workshop
    • Place of Presentation
      東京
    • Related Report
      2009 Final Research Report
  • [Presentation] Sequencing of bacterial genomes and metagenomes2007

    • Author(s)
      服部
    • Organizer
      Metagenomics 2007
    • Place of Presentation
      米国サンディエゴ
    • Related Report
      2009 Final Research Report
  • [Book] 遺伝子医学の最前線と次世代シーケンサー(メタゲノミクスとヒト腸内細菌叢の機能 実験医学増刊号, 実験医学, 27(12))2009

    • Author(s)
      服部
    • Publisher
      羊土社
    • Related Report
      2009 Final Research Report
  • [Book] 感染・炎症・免疫(腸内細菌叢のメタゲノム解析とヒト生物学への展開, 39(1))2009

    • Author(s)
      服部
    • Publisher
      医薬の門社
    • Related Report
      2009 Final Research Report
  • [Book] ヒトの腸内細菌叢の全体像-メタゲノム解析から見えてきたこと-(科学 78(1))2008

    • Author(s)
      服部
    • Publisher
      岩波書店
    • Related Report
      2009 Final Research Report
  • [Book] ヒトゲノム完全解読から「ヒト」理解へ2005

    • Author(s)
      服部正平
    • Total Pages
      294
    • Publisher
      東洋書店
    • Related Report
      2005 Annual Research Report
  • [Remarks] 内容:ヒト腸内細菌叢を構成する腸内細菌のゲノム配列と遺伝子アミノ酸配列情報/ヒト腸内細菌叢メタゲノムデータベース

    • URL

      http://metagenome.jp/microbes/

    • Related Report
      2009 Final Research Report
  • [Remarks] 報道関連情報(朝日新聞2005. 11. 26;毎日新聞2006. 10. 13;日刊工業新聞2006. 12. 7;朝日新聞2007. 7. 23;日経新聞2007. 9. 17;毎日新聞2007. 10. 19;日経新聞2007. 10. 7;読売新聞2008. 7. 6;読売新聞2008. 11. 17; NHKサイエンスゼロ2008. 7. 26)

    • Related Report
      2009 Final Research Report

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Published: 2005-04-01   Modified: 2018-03-28  

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