Analysis of tectal layer formation and mechanisms of retinotectal projection.

• Project/Area Number: 17023003
• Research Category: Grant-in-Aid for Scientific Research on Priority Areas
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Tohoku University
• Principal Investigator: NAKAMURA Harukazu Tohoku University, 大学院・生命科学研究科, 教授 (90079690)
• Co-Investigator(Kenkyū-buntansha): FUNAHASHI Jun-Ichi 東北大学, 加齢医学研究所, 准教授 (00270827) ; WATANABE Yuji 東北大学, 大学院・生命科学研究科, 助教 (80301042) ; OMI Minoru 東北大学, 大学院・生命科学研究科, 助教 (00400416)
• Project Period (FY): 2005 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥109,100,000 (Direct Cost: ¥109,100,000); Fiscal Year 2009: ¥20,900,000 (Direct Cost: ¥20,900,000); Fiscal Year 2008: ¥20,700,000 (Direct Cost: ¥20,700,000); Fiscal Year 2007: ¥21,100,000 (Direct Cost: ¥21,100,000); Fiscal Year 2006: ¥21,400,000 (Direct Cost: ¥21,400,000); Fiscal Year 2005: ¥25,000,000 (Direct Cost: ¥25,000,000)
• Keywords: ニワトリ胚 / 網膜視蓋投射 / 視蓋 / EphrinA2 / EphrinA5 / Fgf8 / En2 / エレクトロポレーション / 視神経線維の標識法 / 峡部オーガナイザー / Ras/ERK経路 / EphrinA2/5 / 視蓋極性 / EhrinA2 / GFP / in ovo electroporation / ERK / Fgf18 / Ras / 中脳視蓋 / Fgf8-Ras-ERKシグナル経路 / Hes5 / En-2

Research Abstract

In lower vertebrates, optic tectum is the visual center and receives retinal fibers in a retinotopic manner. We have shown that Ephrin A2 and A5, which are expressed in the posterior tectum and repel temporal retinal fibers, are induced by Fgf8, but that signal transduction to induce Ephrin A2 and A5 are different. We have elaborated new fiber tracing method, and unraveled new but transient retinotectal pathway which invade deeper layer of the tectum from the first.

Research Products

• [Journal Article] Conditional knockdown of target gene expression by tetracycline regulated transcription of double strand RNA. Dev Growth Differ 53, 69-75 (2011)
  • Author(s): Hou, X., Omi, M., Harada, H., Ishii, S., Takahashi, Y., Nakamura, H.
  • Journal Title: Dev Growth Differ Volume: 53 Pages: 69-75
  • Peer Reviewed
• [Journal Article] Genetically-defined lineage tracing of Nkx2.2-expressing cells in chick spinal cord. (2011)
  • Author(s): Gotoh H, Ono K, Takebayashi H, Harada H, Nakamura H, Ikenaka K
  • Journal Title: Dev Biol Volume: 349 Pages: 504-511
  • Peer Reviewed
• [Journal Article] Protogenin mediates cell adhesion for ingression and re-epithelialization of the paraxial mesodermal cells. Dev Biol. 351, 13-24. (2011)
  • Author(s): Ito, K., Nakamura, H., Watanabe, Y.
  • Journal Title: Dev Biol Volume: 351 Pages: 13-24
  • Peer Reviewed
• [Journal Article] Activation of Ras-ERK pathway by Fgf8 and its downregulation by Sprouty2 for the isthmus organizing activity (2010)
  • Author(s): Suzuki-Hirano A, Harada H, Sato T, Nakamura H
  • Journal Title: Dev Biol 337 Pages: 284-293
• [Journal Article] Activation of Ras-ERK pathway by Fgf8 and its downregulation by Sprouty2 for the isthmus organizing activity (2010)
  • Author(s): Suzuki-Hirano, A., Harada, H., Sato, T., Nakamura, H.
  • Journal Title: Dev Biol Volume: 337 Pages: 284-293
  • Peer Reviewed
• [Journal Article] Gene manipulation of chick embryos in vitro, EC culture, and long survival in transplanted eggs (2010)
  • Author(s): Tanaka, J., Harada, H., Ito, K., Ogura, T., Nakamura, H.
  • Journal Title: Dev Growth Differ. Volume: 52 Pages: 629-634
  • Peer Reviewed
• [Journal Article] Expression of chick Coactosin in cells in morphogenetic (2009)
  • Author(s): Hou X, Katahira T, Kimura J, Nakamura H
  • Journal Title: Dev Growth Differ 51 Pages: 833-840
• [Journal Article] R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development. (2008)
  • Author(s): Aoki M, Kiyonari H, Nakamura H, Okamoto H
  • Journal Title: Dev Growth Differ 50 Pages: 885-895
  • NAID: 10021095550
• [Journal Article] Isthmus organizer for mesencephalon and metencephalon. (2008)
  • Author(s): Nakamura H, Sato T, Suzuki-Hirano A
  • Journal Title: Dev Growth Differ 50
  • NAID: 10024399510
• [Journal Article] Electroporation as an efficient method of gene transfer. (2008)
  • Author(s): Odani N, Ito K, Nakamura H
  • Journal Title: Dev Growth Differ 50 Pages: 443-448
  • NAID: 10021097110
• [Journal Article] Tracing retinal fiber trajectory with a method of transposon-mediated genomic integration in chick embryo. (2008)
  • Author(s): Harada H, Takahashi Y, Kawakami K, Ogura T, Nakamura H
  • Journal Title: Dev Growth Differ 50 Pages: 697-702
  • NAID: 10022020746
• [Journal Article] Electroporation in avian embryos (2008)
  • Author(s): Funahashi, J., Nakamura H.
  • Journal Title: Methods Mol Biol 461 Pages: 377-378
  • Peer Reviewed
• [Journal Article] Tracing retinal fiber trajectory with a method of transposon-mediated genomic integration in chick embryo (2008)
  • Author(s): Harada, H., Takahashi, Y., Kawakami, K., Ogura, T., Nakamura, H
  • Journal Title: Dev Growth Differ 50 Pages: 697-702
  • NAID: 10022020746
  • Peer Reviewed
• [Journal Article] Electroporation as an efficient method bf gene transfer (2008)
  • Author(s): Odani, N., Nakamura, H.
  • Journal Title: Dev Growth Differ 50 Pages: 443-448
  • Peer Reviewed
• [Journal Article] Isthmus organizer for mesencephalon and metencephalon. (2008)
  • Author(s): Nakamura, H., Sato, T. & Suzuki-Hirano, A.
  • Journal Title: Dev Growth Differ 50(In press)
  • NAID: 10024399510
  • Peer Reviewed
• [Journal Article] Electroporation as an efficient method of gene transfer. (2008)
  • Author(s): Odani, N. & Nakamura, H.
  • Journal Title: Dev Growth Differ 50(In press)
  • NAID: 10021097110
  • Peer Reviewed
• [Journal Article] R-Spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development. (2008)
  • Author(s): Aoki, M., Kiyonari, H., Nakamura, H. & Okamoto, H.
  • Journal Title: Dev Growth Differ 50 Pages: 85-95
  • NAID: 10021095550
  • Peer Reviewed
• [Journal Article] 峡部オーガナイザーと小脳分化制御・視蓋極性形成および網膜視蓋投射形成 (2008)
  • Author(s): 仲村春和、杉山清佳、佐藤達也、鈴木-平野明日香
  • Journal Title: 蛋白質核酸酵素 53 Pages: 373-378
• [Journal Article] R-spondin3 is required for mouse placental development. (2007)
  • Author(s): Aoki M, Mieda M, Ikeda T, Hamada Y, Nakamura H, Okamoto H
  • Journal Title: Dev Biol 301 Pages: 218-226
• [Journal Article] Cloning and developmental expression of a chick G-protein-coupled receptor SCGPR1. (2007)
  • Author(s): Odani N, Pfaff SL, Nakamura H, Funahashi J
  • Journal Title: Gene Exp Pat 7 Pages: 375-380
• [Journal Article] Role of Bone morphogenetic protein 4 in zebrafish semicircular canal development. (2007)
  • Author(s): Omata, Y., Nojima, Y., Nakayama, S., Okamoto, H., Nakamura, H. & Funahashi, J.
  • Journal Title: Dev Growth Differ 49 Pages: 711-719
  • NAID: 10019984157
  • Peer Reviewed
• [Journal Article] Cloning and developmental expression of a chick G-protein-coupled receptor SCGPR1 (2007)
  • Author(s): Odani N, Pfaff SL, Nakamura H, Funahashi J
  • Journal Title: Gene Expr Patterns 7 Pages: 375-380
  • Peer Reviewed
• [Journal Article] Functional analysis of chick ONT1 reveals distinguishable activities among olfactomedin-related signaling factors. (2006)
  • Author(s): Sakuragi M, Sasai N, Ikeya M, Kawada M, Onai T, Katahira T, Nakamura H, Sasai Y
  • Journal Title: Mech Devel 123 Pages: 114-123
• [Journal Article] Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance. (2006)
  • Author(s): Matsunaga E, Nakamura H, Chedotal A
  • Journal Title: J Neurosci 26 Pages: 6082-6088
• [Journal Article] Cloning and developmental expression of a chick G-protein-coupled receptor SCGPR1 (2006)
  • Author(s): Odani, N., Pfaff, S.L., Nakamura, H., Funahashi, J
  • Journal Title: Gene. Exp. Pattern 7 Pages: 357-380
• [Journal Article] Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance. (2006)
  • Author(s): Matsunaga, E., Nakamura, H., Chedotal, A.
  • Journal Title: J. Neurosci 26 Pages: 6082-6088
• [Journal Article] R-spondin3 is require for mouse placental development. (2006)
  • Author(s): Aoki, M., Mieda, M., Ikeda, T., Hamada, Y., Nakamura, H., Okamoto, H.
  • Journal Title: Dev. Biol. 301 Pages: 218-226
• [Journal Article] Role of Gbx2 and Otx2 in the formation of cochlear ganglion and endolymphatic duct. (2006)
  • Author(s): Miyazaki, H., Kobayashi, T., Nakamura, H., Funahashi, J.
  • Journal Title: Dev. Growth Differ. 48 Pages: 429-438
  • NAID: 10020141479
• [Journal Article] Functional Analysis of Chick ONT1 Reveals Distinguishable Activities among Olfactomedin-Related Related Signaling Factors. (2006)
  • Author(s): Sakuragi, M., Sasai, N., Ikeya, M., Kawada, M., Katahira, T., Nakamura, H., Sasai, Y.
  • Journal Title: Mech Develop. 123 Pages: 114-123
• [Journal Article] Regulation of isthmic Fgf8 signal by sprouty2. (2005)
  • Author(s): Suzuki-Hirano A, Sato T, Nakamura H
  • Journal Title: Development 132 Pages: 257-265
• [Journal Article] Isthmus organizer and regionalization of the mesencephalon and metencephalon. (2005)
  • Author(s): Nakamura H, Watanabe Y
  • Journal Title: Int J Dev Biol 49 Pages: 231-235
• [Journal Article] Identification of protogenin, a novel immunoglobulin superfamily gene expressed during early chick embryogenesis. (2005)
  • Author(s): Toyoda R, Nakamura H, Watanabe Y
  • Journal Title: Gene Exp Pat 5 Pages: 778-785
• [Journal Article] Isthmus organizer for midbrain and hindbrain development. (2005)
  • Author(s): Nakamura H, Katahira T, Matsunaga E, Sato T
  • Journal Title: Brain research.Brain Res Rev 49 Pages: 120-126
• [Journal Article] Regulation of isthmic Fgf8 signal by Sprouty2 (2005)
  • Author(s): Suzuki-Hirano, A., Sato, Nakamura, H.
  • Journal Title: Development 132 Pages: 257-265
• [Journal Article] Identification of retinotectal projection pathway in the deep tectal laminae in the chick.
  • Author(s): Omi M, Harada H, Nakamura H.
  • Journal Title: J Comp Neurol 2011
• [Presentation] Novel retinotectal projection pathway in deeper laminae of the developing chick optictectum (2011)
  • Author(s): Minoru Omi, Hidekiyo Harada, Harukazu Nakamura
  • Organizer: The 1st Tohoku International Symposium on Multidisciplinary Neuroscience
  • Place of Presentation: 仙台
  • Year and Date: 2011-01-21
• [Presentation] FGF8 localizes in the nucleus The possibility of new function (2011)
  • Author(s): Ayumu Suzuki, Hidekiyo Harada, Harukazu Nakamura
  • Organizer: The 1st Tohoku International Symposium on Multidisciplinary Neuroscience
  • Place of Presentation: 仙台
  • Year and Date: 2011-01-21
• [Presentation] Involvement of Pea3/Ets transcription factor Erm in the neuronal axis formation by repressing Shh expression (2010)
  • Author(s): 原田英斉, 尾身実, 佐藤達也, 仲村春和
  • Organizer: BMB2010第33回日本分子生物学会年会
  • Place of Presentation: 神戸
  • Year and Date: 2010-12-10
• [Presentation] SOX5 is required for semicicular canal development in Zebrafish (2010)
  • Author(s): Sympei Tanino, Gembu Abe, Koichi Kawakami, Harukazu Nakamura, Jun-ichi Funahashi
  • Organizer: BMB2010第33回日本分子生物学会年会
  • Place of Presentation: 神戸
  • Year and Date: 2010-12-10
• [Presentation] ニワトリ胚網膜視蓋投射における新規軸索経路 (2010)
  • Author(s): 尾身実, 原田英斉, 仲村春和
  • Organizer: 日本動物学会第81回大会
  • Place of Presentation: 東京
  • Year and Date: 2010-09-25
• [Presentation] New retinotectal projection pathway in deeper laminae of the developing chick optictectum (2010)
  • Author(s): Minoru Omi, Hidekiyo Harada, Harukazu Nakamura
  • Organizer: 第43回日本発生生物学会
  • Place of Presentation: 京都
  • Year and Date: 2010-06-22
• [Presentation] Visualization of tangential neuronal migration in the developing chick optic tectum (2010)
  • Author(s): Yuji Watanabe, Harukazu Nakamura
  • Organizer: 第43回日本発生生物学会
  • Place of Presentation: 京都
  • Year and Date: 2010-06-21
• [Presentation] Analysis of translocation of Fgf8 to the nuclei (2010)
  • Author(s): Ayumu Suzuki, Hidekiyo Harada, Harukazu Nakamura
  • Organizer: 第43回日本発生生物学会
  • Place of Presentation: 京都
  • Year and Date: 2010-06-21
• [Presentation] Organizing signal for development of the tectum and cerebellum. (2010)
  • Author(s): Harukazu Nakamura
  • Organizer: UCL-Tohoku University Symposium, From Cell/Developmental Biology to Neuroscience. organizers : Harukazu Nakamura & Shin-ichi Ohnuma
  • Place of Presentation: London
  • Year and Date: 2010-03-15
• [Presentation] Organizing signal for development of the tectum and cerebellum. (2010)
  • Author(s): Harukazu Nakamura
  • Organizer: UCL-Tohoku University Symposium
  • Place of Presentation: London、United Kingdom
  • Year and Date: 2010-03-15
• [Presentation] 脳の設計図とその書き換えによる自在な脳の作り替え (2009)
  • Author(s): 仲村春和
  • Organizer: 第2回東北大学バイオフォーラム～脳科学の革新的な発展を目指して～
  • Place of Presentation: 東京ステーションコンファランス
  • Year and Date: 2009-06-05
• [Presentation] Transient innervation of retinal axons to the deeper laminae prior to establishment of the lamina-specific projection in chick optic tectum. (2009)
  • Author(s): Minoru Omi, Hidekiyo Harada, Harukazu Nakamura
  • Organizer: 16th International Society of Developmental Biologists Congress, Edinburgh.
  • Place of Presentation: UK
• [Presentation] Coordination of midbrain A-P and D-V axis formation by mutual-repression of FGF and SHH signaling. (2009)
  • Author(s): Hidekiyo Harada, Tatsuya Sato, Harukazu Nakamura
  • Organizer: 16th International Society of Developmental Biologists Congress, Edinburgh.
  • Place of Presentation: UK
• [Presentation] Fgf signaling in tectal polarity formation. (2008)
  • Author(s): Harada, H., Nakamura, H.
  • Organizer: Godon Conference' Fibroblast Growth Factors in Development & Disease'
  • Place of Presentation: Il Ciocco, Italy
• [Presentation] Regulation of ERK phosphorylation for the MHB formation and cerebellar development. (2008)
  • Author(s): Suzuki-Hirano, A., Sato, T., Nakamura, H.
  • Organizer: Gordon Conference 'Fibroblast Growth Factors in Development & Disease'
  • Place of Presentation: Il Ciocco, Italy
• [Presentation] Regulation of the Fgf8-Ras-ERK signaling pathway for cerebellar development. (2008)
  • Author(s): Suzuki A., Sato T., Nakamura, H.
  • Organizer: ZAO Conference, The 1^<st> International Conference of Tohoku Neuroscience GCOE, "from GENES to DEVELOPMENT and BEHAVIOR"
  • Place of Presentation: Miyagi Zao Royal Hotel
• [Presentation] Fgf signaling and En2 for tectal polarity formation. (2008)
  • Author(s): Harada, H.Tanaka, J.Matsuda, Y.Suzuki-Hirano, A.Nakamura, H.
  • Organizer: ZAO Conference, The 1^<st> International Conference of Tohoku Neuroscience GCOE, "from GENES to DEVELOPMENT and BEHAVIOR"
  • Place of Presentation: Miyagi Zao Royal Hotel
• [Presentation] Analysis of coactosin, an actin binding protein, in neural crest cell migration. (2008)
  • Author(s): Hou X.Katahira T.Kimura J.Nakamura H.
  • Organizer: ZAO Conference, The 1^<st> International Conference of Tohoku Neuroscience GCOE, "from GENES to DEVELOPMENT and BEHAVIOR"
  • Place of Presentation: Miyagi Zao Royal Hotel
• [Presentation] Protogenin (PRTG) is involved in gastrulation cell movement. (2008)
  • Author(s): Ito, K.Toyoda, R.Nakamura, H.Watanabe, Y.
  • Organizer: ZAO Conference, The 1^<st> International Conference of Tohoku Neuroscience GCOE, "from GENES to DEVELOPMENT and BEHAVIOR"
  • Place of Presentation: Miyagi Zao Royal Hotel
• [Presentation] Analysis of EphrinA2/A5 expressioin in the optic tectum. (2008)
  • Author(s): Tanaka, J., Harada, H., Nakamura, H.
  • Organizer: ZAO Conference, The 1st International Conference of Tohoku Neuroscience GCOE, "from GENES to DEVELOPMENT and BEHAVIOR"
  • Place of Presentation: Miyagi Zao Royal Hotel
• [Presentation] Fgf 8 for ephrinA 2/A 5 expression in chick optic tectum (2008)
  • Author(s): Tanaka, J., Harada, H., Nakamura, H.
  • Organizer: 41 st Annual Meeting for the Japanese Society of Developmental Biologists
  • Place of Presentation: 徳島市
• [Presentation] Regulation of the Fgf8-Ras-ERK signaling pathway for cerebellar development. (2008)
  • Author(s): Suzuki A., Sato T. & Nakamura, H.
  • Organizer: ZAO Conference, The 1st International Conference of Tohoku Neuroscience GCOE, "from GENES to DEVELOPMENT and BEHAVIOR"
  • Place of Presentation: Zao Royal Hotel, Miyagi, Japan
• [Presentation] Fgf signalingin tectal polarity formation. (2008)
  • Author(s): Harada, H. & Nakamura, H.
  • Organizer: Gordon Conference, Fibroblast Growth Factors in Development & Disease.
  • Place of Presentation: II Ciocco, ltaly
• [Presentation] Regulation of ERK phosphorylation for the MHB formation and cerebellar development. (2008)
  • Author(s): Suzuki-Hirano, A. & Nakamura, H.
  • Organizer: Gordon Conference, Fibroblast Growth Factors in Development & Disease.
  • Place of Presentation: II Ciocco, ltaly
• [Presentation] Establishment of anteroposterior axis of the chick optic tectum by Fgf-Ras-ERK signaling. (2007)
  • Author(s): Harada, H., Matsuda, Y., Tanaka, J., Suzuki-Hirano, A., Nakamura, H.
  • Organizer: International Chick Meeting
  • Place of Presentation: Barcelona, Spain.
• [Presentation] Analysis of coactosin, an actin binding protein, in neural crest cell migration. (2007)
  • Author(s): Hou, X., Katahira, T., Kimura, J. , 仲村春和
  • Organizer: International Chick Meeting
  • Place of Presentation: Barcelona, Spain.
• [Presentation] Sequential regulations of ERK signaling activity and celebellar development. (2007)
  • Author(s): Suzuki-Hirano, A., Sato, T. , Nakamura, H.
  • Organizer: International Chick Meeting
  • Place of Presentation: Barcelona, Spain.
• [Presentation] Establishment of anteroposterior axis of the chick optic tectum by Fgf-Ras-ERK signaling. (2007)
  • Author(s): Harada, H., Matsuda, Y., Tanaka, J., Suzuki-Hirano, A., & Nakamura, H.
  • Organizer: International Chick Meeting
  • Place of Presentation: Barcelona, Spain
• [Presentation] Analysis of coactosin, an actin binding protein, in neural crest cell migration (2007)
  • Author(s): Hou, X., Katahira, T., Kimura, J., & Nakamura, H.
  • Organizer: International Chick Meeting
  • Place of Presentation: Barcelona, Spain
• [Presentation] Sequential regulations of ERK signaling activity and ceebellar development. (2007)
  • Author(s): Suzuki-Hirano, A., Sato, T., & Nakamura, H.
  • Organizer: International Chick Meeting
  • Place of Presentation: Barcelona, Spain
• [Presentation] Role of En2 and Fgf signaling in tectal polarity formation (2007)
  • Author(s): H. HARADA, J. TANAKA, Y. MATUSDA, A. SUZUKI-HIRANO, ^*H. NAKAMURA
  • Organizer: SFN2007
  • Place of Presentation: San Diego, USA
• [Presentation] 「脳を組み立てる」生命科学研究科シンポジューム「脳と社会」 (2006)
  • Author(s): 仲村春和
  • Organizer: 東北大学脳研究者プラットフォーム
  • Place of Presentation: 仙台市
  • Year and Date: 2006-11-13
• [Presentation] Regulation of Fgf8 signaling for the cerebellar development : Special attention paid to ERK activity level. (2006)
  • Author(s): Suzuki-Hirano, A, Sato,T., Nakamura, H.
  • Organizer: Neuroscience2006.
  • Place of Presentation: Atlanta.
• [Presentation] Pea3/Ets transcription factors as downstream factors of Fgf8-Ras-Erk signaling around the isthmic organizer. (2006)
  • Author(s): Harada, H, Sato,T., Nakamura, H.
  • Organizer: Neuroscience2006.
  • Place of Presentation: Atlanta.
• [Presentation] Expression of Canopy2 in the optic tectum and its involvement in cell proliferation. (2006)
  • Author(s): Harada, H., Sato, T., Hirate, Y,. Okamoto, H., Nakamura, H.
  • Organizer: 20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress
  • Place of Presentation: Kyoto.
• [Presentation] Analysis of Ras-ERK signaling pathway for the cerebellar development. (2006)
  • Author(s): Suzuki-Hirano, A., Sato, T., Nakamura, H.
  • Organizer: 20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11^<th> FAOBMB Congress
  • Place of Presentation: Kyoto.
• [Presentation] Regulation of Ras-ERK signaling pathway for cerebellar development. (2006)
  • Author(s): Sato, T., Nakamura, H.
  • Organizer: Gordon Conference : Fibroblast Growth Factors in Development & Disease. Organizers : Olwin B.B., Ornitz, D.M.
  • Place of Presentation: Ventura, CA, USA
• [Presentation] Hes5 expression and rostrocaudal polarity formation of the tectum. (2005)
  • Author(s): Katahira, T., Kimura, J. Watanabe, Y., Nakamura, H.
  • Organizer: 35nd Annual Meeting of Society for Neuroscience.
  • Place of Presentation: Washington, DC.
• [Presentation] Isthmus organizing signal for the tectum and cerebellard evelopment. (2005)
  • Author(s): Nakamura, H., Sato, T., Suzuki, A.
  • Organizer: 2^<nd> International Symposium and annual meeting of Dynamics of Developmental System
  • Place of Presentation: Kisarazu, Chiba
• [Presentation] Regionalization and laminar formation of the optic tectum in relation to retinotectal projection map. Symposium 'Formation, Development and Function of Neural Circuit' Organizer M. Kano & T. Manabe (2005)
  • Author(s): Harukazu Nakamura
  • Organizer: The 28^<th> Annual Meeting of the Japan Neuroscience Society
  • Place of Presentation: Yokohama
• [Book] Electroporation and Sonoporation in Developmental Biology (2009)
  • Author(s): 仲村春和(編集)
  • Total Pages: 331
  • Publisher: シュプリンガージャパン
• [Book] Electroporation and Sonoporation in Developmental Biology (2009)
  • Author(s): Harukazu Nakamura(editor)
  • Total Pages: 331
  • Publisher: Springer Japan
• [Book] Methods in Molecular Biology, Vol 461: Molecular Embryology: Meht-hods and Protocols, 2nd ed(Electroporation as an efficient method of gene transfer) (2008)
  • Author(s): Funahashi, J., Nakamura, H. (eds. P. Sharpe and I. Mason)
  • Publisher: Humana Press, Totowa, NJ.(印刷中)
• [Book] Encyclopedia of Neuroscience (Regionalization of the vertebrate central nervous system) (2008)
  • Author(s): Nakamura, H
  • Publisher: Springer-Verlag(印刷中)
• [Book] 加齢医学 (2007)
  • Author(s): 仲村春和
  • Publisher: 東北大学出版会
• [Book] 加齢医学(第VII章 脳はいかにしてかたちづくられるか) (2007)
  • Author(s): 仲村春和(帯刀益夫、佐竹正延編)
  • Total Pages: 300
  • Publisher: 東北大学出版会
• [Remarks] ホームページ等
  • URL: http://www.idac.tohoku.ac.jp/dep/molneuro/Dept_Mol_Neurobiol/Welcome.html
• [Remarks]
  • URL: http://www.lifesci.tohoku.ac.jp/outline/neuro/neuroscience/molecular_neurobiology.html