| Budget Amount *help |
¥123,000,000 (Direct Cost: ¥123,000,000)
Fiscal Year 2009: ¥22,800,000 (Direct Cost: ¥22,800,000)
Fiscal Year 2008: ¥24,600,000 (Direct Cost: ¥24,600,000)
Fiscal Year 2007: ¥24,600,000 (Direct Cost: ¥24,600,000)
Fiscal Year 2006: ¥26,400,000 (Direct Cost: ¥26,400,000)
Fiscal Year 2005: ¥24,600,000 (Direct Cost: ¥24,600,000)
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| Research Abstract |
Genetic change in meiosis is driven by homologous recombination. The recombination not only generates diversity in the genome, but also plays an essential role in chromosome segregation at meiosis I. Meiotic recombination is mechanistically different from that in mitosis with more complex regulation. From this study, we have identified several key proteins/genes in the recombination which tell us a new idea on the mechanisms of meiotic recombination. Particularly, we have identified an active role of chromosome dynamics and structure in the control of the recombination.
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