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Transportsome on biomembrane systems: its molecular assembly and physiological function.

Research Project

Project/Area Number 17081015
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionOsaka University (2007-2010)
Kyorin University (2005-2006)

Principal Investigator

KANAI Yoshikatsu  大阪大学, 医学系研究科, 教授 (60204533)

Co-Investigator(Kenkyū-buntansha) MORI Yasuo  京都大学, 工学研究科, 教授 (80212265)
TAKESHIMA Hiroshi  京都大学, 薬学研究科, 教授 (70212024)
SUZUKI Hiroshi  東京大学, 医学部附属病院, 教授 (80206523)
Project Period (FY) 2005 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥23,600,000 (Direct Cost: ¥23,600,000)
Fiscal Year 2010: ¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2009: ¥6,200,000 (Direct Cost: ¥6,200,000)
Fiscal Year 2008: ¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2007: ¥5,700,000 (Direct Cost: ¥5,700,000)
Fiscal Year 2006: ¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 2005: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywords輸送体 / プロスタグランジン / 傍糸球体装置 / 近位尿細管 / レニン / 膜輸送 / トランスポーター / 複合体 / 生体膜 / 上皮輸送 / イオンチャネル / 分子複合体 / ポンプ / 生体恒常性
Research Abstract

本終了研究領域は、膜輸送複合体トランスポートソームの実体の解明とその生理的意義の実証を目的としたものであるが、トランスポートソームの実体についての統合的共通概念の定式化とトランスポートソームの概念の定着化のため、終了研究領域の総括班員(本研究の代表者及び研究分担者)が中心となり、終了研究領域の計画研究代長者が連携研究者として加わり、終了研究領域の取りまとめを以下のように行った。(1)トランスポートソームの整理と体系付け。本領域研究の成果を総合して、「トランスポートソームの基本型」の分類表を作成した。この表は、「タンパク質相互作川により形成されるもの」と「場に依存して形成されるもの」の大分類のもとに、13類型のトランスポートソームの基本型とそれぞれの実例からなる。トランスポートソームデータベースの基本となる分類表であるとともに、これをガイドとしながら新たな研究を展開する推進力をもつ分類表となった。この分類表は、領域ホームページで公開するとともに、領域で編集した2つの総説集/解説書、および国際学術誌Channelsの特集号でも解説を加えて紹介した。(2)トランスポートソームの概念の定着化。トランスポートソームの体系を解説した解説弁を、領域関係者が分担執筆し、発行した。また、トランスポートソームの総説集を編集し、領域関係者が中心となり執筆した。加えて、本領域が創刊に貢献した国際学術誌Channelsにトランスポートソームの特集号を組み、編集した。領域ニュースレターとして好評であった「TRANSPORTSOME」の総集編を作成し、発行した。本取りまとめに際し、研究代表者と研究分担者は、計11回の取りまとめ会議を開催し、取りまとめ作業を共同で実施した。以上により、トランスポートソームの概念を定着させ、またトランスポートソーム概念の確立における本特定領域研究の寄与と功績を明示して、終了研究領域の取りまとめとした。

Report

(7 results)
  • 2010 Annual Research Report
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (333 results)

All 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article (263 results) (of which Peer Reviewed: 157 results) Presentation (48 results) Book (16 results) Remarks (5 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] SGLT阻害薬 次世代の2型糖尿病薬物治療2011

    • Author(s)
      金井好克
    • Journal Title

      Mebio

      Volume: 28 Pages: 111-117

    • Related Report
      2010 Annual Research Report
  • [Journal Article] NPC2 regulates biliary cholesterol secretion via stimulation of ABCG5/G8-mediated cholesterol transport.2011

    • Author(s)
      Yamanashi Y, Takada T, Shoda J, Suzuki H.
    • Journal Title

      Gastroenterology

      Volume: (In press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Receptor for activated C-kinase 1 regulates the cell surface expression and function of ATP binding cassette G2.2010

    • Author(s)
      Ikebuchi Y, Ito K, Takada T, Anzai N, Kanai Y, Suzuki H.
    • Journal Title

      Drug Metab Dispos.

      Volume: 38 Pages: 2320-2328

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules.2010

    • Author(s)
      Shiraya K, Hirata T, Hatano R, Nagamori S, Kanai Y, et al.
    • Journal Title

      J Biol Chem.

      Volume: 285 Pages: 22141-22151

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 癌のアミノ酸トランスポーターと代謝制御(解説/特集)癌の代謝 正常組織との代謝特性の違いから見えてくる新たな診断・治療戦略2010

    • Author(s)
      金井好克
    • Journal Title

      細胞工学

      Volume: 30 Pages: 41-46

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 薬理学からみた脳卒中 関連領域からみた脳卒中(第34回)2010

    • Author(s)
      金井好克
    • Journal Title

      分子脳血管病

      Volume: 9 Pages: 422-429

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 新たなNa調節系(解説/特集)体液恒常性機構と臨床2010

    • Author(s)
      金井好克
    • Journal Title

      腎臓

      Volume: 33 Pages: 6-11

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca^<2+> channels.2010

    • Author(s)
      Uriu Y, Kiyonaka S, Miki T, Yagi M, Mori Y., et al.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 21750-21567

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Charade of the SR K^<+->channel : two ion-channels, TRIC-A and TRIC-B, masquerade as a single K^<+->channel.2010

    • Author(s)
      Pitt S J, Park K-H, Nishi M, Takeshima H, et al.
    • Journal Title

      Biophys.J.

      Volume: 99 Pages: 417-426

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imparied Orail-mediateded resting Ca^<2+> entry reduces the cytosolic [Ca^<2+>] and SR Ca^<2+> loading in quitescent junctophilin1 knockout myotubes.2010

    • Author(s)
      Li H, Ding X, Lopez J R, Takeshima H, Ma J, Allen P D, Eltit J M.
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 39171-39179

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Receptor for activated C-kinase 1 regulates the cell surface expression and function of ATP binding cassette G2.2010

    • Author(s)
      Ikebuchi Y, Ito K, Takada T, Anzai N, Kanai Y, Suzuki H.
    • Journal Title

      Drug Metab Dispos

      Volume: 38 Pages: 2320-2328

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules.2010

    • Author(s)
      Shiraya K, Hirata T, Hatano R, Nagamori S, Wiriyasermkul P, Jutabha P, Matsubara M, Muto S, Tanaka H, Asano S, Anzai N, Endou H, Yamada A, Sakurai H, Kanai Y.
    • Journal Title

      J Biol Chem. 285

      Pages: 22141-22151

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.2010

    • Author(s)
      Koike C, Obara T, Uriu Y, Numata T, Sanuki R, Miyata K, Koyasu T, Ueno S, Funabiki K, Tani A, Ueda H, Kondo M, Mori Y, Tachibana M, Furukawa T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 107

      Pages: 332-337

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Rim2α determines docking and priming states in insulin granule exocytosis.2010

    • Author(s)
      Yasuda T, Shibasaki T, Minami K, Takahashi H, Mizoguchi A, Uriu Y, Numata T, Mori Y, Miyazaki JI, Miki T, Seino S.
    • Journal Title

      Cell Metab. 12

      Pages: 117-129

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] L-type amino acid transporter 1 inhibitors inhibit tumor cell growth.2010

    • Author(s)
      Oda K, Hosoda N, Endo H, Saito K, Tsujihara K, et al.
    • Journal Title

      Cancer Sci. 101

      Pages: 173-179

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Ca^<2+> Channel Synprint Site in Synaptic Vesicle Endocvtosis.2010

    • Author(s)
      Watanabe H, Yamashita T, Saitoh N, Kiyonaka S, et al.
    • Journal Title

      J.Neurosci. 30

      Pages: 655-660

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRPM 1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade.2010

    • Author(s)
      Koike C, Obara T, Uriu Y, Numata T, Sanuki R, et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 107

      Pages: 332-337

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A pathogenic C-terminus-truncated Polycistin-2 mutant enhances receptor-activated Ca^<2+> entry via association with TRPC3 and TRPC7.2010

    • Author(s)
      Miyagi K, Kiyonaka S, Yamada K, Miki T, et al.
    • Journal Title

      J.Biol.Chem. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Knockdown of Ca_v2.1 calcium channels is sufficient to induce neuro-logical disorders observed in natural occurring Cacna1a mutants in mice2010

    • Author(s)
      Saito H, Okada M, Miki T, Wakamori M, et al.
    • Journal Title

      Biochem.Biophys.Res.Comm. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An in vivo fluorescent sensor reveals intracellular Ins(1,3,4,5)P(4) dynamics in single cells.2010

    • Author(s)
      Sakaguchi R, Tainaka K, Shimada N, Nakano S, et al.
    • Journal Title

      Angew.Chem.Int.Ed. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ca^<2+> influx and protein scaffolding via TRPC3 sustain PKCβ and ERK activation in B cells.2010

    • Author(s)
      Numaga T, Nishida M, Kiyonaka S, Kato K, et al.
    • Journal Title

      J.Cell Sci. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential redox regulation of ORAI channels : a mechanism to tune cellular calcium responses.2010

    • Author(s)
      Bogeski I, Kummerow C, Al-Ansary D, Koehler R, et al.
    • Journal Title

      Science Signaling (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A missense mutation of the gene encoding voltage-dependent sodium channel (Na_v1.1) confers susceptibility to febrile seizures in rats.2010

    • Author(s)
      Mashimo T, Ohmori I, Ouchida M, Ohno Y, et al.
    • Journal Title

      J.Neurosci. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common Defects of ABCG2, a High-capacity Urate Exporter, Cause Gout : A Function-based Genetic Analysis in a Japanese Population.2009

    • Author(s)
      Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, Ikebuchi Y, Ito K, Kusanagi Y, Chiba T, Tadokoro S, Takada Y, Oikawa Y, Inoue H, Suzuki K, Okada R, Nishiyama J, Domoto H, Watanabe S, Fujita M, Morimoto Y, Naito M, Nishio K, Hishida A, Wakai K, Asai Y, Niwa K, Kamakura K, Nonoyama S, Sakurai Y, Hosoya T, Kanai Y, Suzuki H, Hamajima N, Shinomiya N.
    • Journal Title

      Science Trans Med. 1

      Pages: 41-48

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.2009

    • Author(s)
      Sun H-S, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP, Golde TE, Orser BA, MacDonald JF, Tymianski M.
    • Journal Title

      Nature Neurosci. 12

      Pages: 1300-1307

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.2009

    • Author(s)
      Kiyonaka S, Kato K, Nishida M, Mio K, Numaga T, Sawaguchi Y, Yoshida T, Wakamori M, Mori E, Numata T, Ishii M, Takemoto H, Ojida A, Watanabe K, Uemura A, Kurose H, Morii T, Kobayashi T, Sato Y, Sato C, Hamachi I, Mori Y.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 106

      Pages: 5740-5745

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A pathogenic C-terminus-truncated Polycistin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.2009

    • Author(s)
      Miyagi K, Kiyonaka S, Yamada K, Miki T, Mori E, Kato K, Numata T, Sawaguchi Y, Numaga T, Kimura T, Kanai Y, Kawano M, Wakamori M, Nomura H, Koni I, Yamagishi M, Mori Y.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 34400-34412

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4.2009

    • Author(s)
      Ikebuchi Y, Takada T, Ito K, Anzai N, Kanai Y, Suzuki H.
    • Journal Title

      Hepatol Res, Hepatol Res. 39

      Pages: 1091-1107

    • NAID

      10027405617

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] (co-corresponding authors) MG53 nucleates assembly of cell membrane repair machinery.2009

    • Author(s)
      Cai C, Masumiya H, Weisleder N, Matsuda N, Nishi M, Hwang M, Ko J-K, Lin P, Thornton A, Zhao X, Pan Z, Komazaki S, Brotto M, Takeshima H, Ma J.
    • Journal Title

      Nature Cell Biol. 11

      Pages: 56-64

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel role of the C-terminus of b0, +AT in the ER-Golgi trafficking of the rBAT-b0, +AT heterodimeric amino acid transporter.2009

    • Author(s)
      Sakamoto S, Chairoungdua A, Nagamori S, Wiriyasermkul P, Promchan K, Tanaka H, Kimura T, Ueda T, Fujimura M, Shigeta Y, Naya Y, Akakura K, Ito H, Endou H, Ichikawa T, Kanai Y.
    • Journal Title

      Biochem J. 417

      Pages: 441-448

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout : A Function-Based Genetic Analysis in a Japanese Population.2009

    • Author(s)
      Hirotaka Matsuo, Tappei Takad, Kimiyoshi Ichida, et al.
    • Journal Title

      Science Translational Medicine 1

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 18F-FMT uptake seen within primary cancer on PET helps predict outcome of non-small cell lung cancer.2009

    • Author(s)
      Kaira K, Oriuchi N, Shimizu K, Tominaga H, et al.
    • Journal Title

      J Nucl Med. 50

      Pages: 1770-1776

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A pathogenic C terminus-truncated polycystin-2 mutant enhances receptor-activated Ca2+ entry via association with TRPC3 and TRPC7.2009

    • Author(s)
      Miyagi K, Kiyonaka S, Yamada K, Miki T, Mori E, et al.
    • Journal Title

      J Biol Chem. 284

      Pages: 34400-34412

    • NAID

      120006334914

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CD98 expression is associated with poor prognosis in resected non-small-cell lung cancer with lymph node metastases.2009

    • Author(s)
      Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, et al.
    • Journal Title

      Ann Surg Oncol. 16

      Pages: 3473-3781

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4.2009

    • Author(s)
      Ikebuchi Y, Takada T, Ito K, Yoshikado T, Anzai N, et al.
    • Journal Title

      Hepatol Res. 39

      Pages: 1091-1107

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer.2009

    • Author(s)
      Imai H, Kaira K, Oriuchi N, Yanagitani N, Sunaga N, et al.
    • Journal Title

      Histopathology 54

      Pages: 804-813

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Significance of system L amino acid transporter 1 (LAT-1) and 4F2 heavy chain (4F2hc) expression in human developing intestines.2009

    • Author(s)
      Ohno C, Nakanishi Y, Honma T, Henmi A, et al.
    • Journal Title

      Acta Histochem Cytochem. 42

      Pages: 73-81

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Amino acid transporter LAT3 is required for podocyte development and function.2009

    • Author(s)
      Sekine Y, Nishibori Y, Akimoto Y, Kudo A, Ito N, et al.
    • Journal Title

      J Am Soc Nephrol. 20

      Pages: 1586-1596

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas2009

    • Author(s)
      Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, et al.
    • Journal Title

      J Surg Oncol. 99

      Pages: 433-438

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma.2009

    • Author(s)
      Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, et al.
    • Journal Title

      Lung Cancer. 66

      Pages: 120-126

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation of angiogenesis with 18F-FMT and 18F-FDG uptake in non-small cell lung cancer.2009

    • Author(s)
      Yamauchi K, Sakurai H,Kimura T, Wiriyasermkul P, et al.
    • Journal Title

      Cancer Lett. 276

      Pages: 95-101

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 栄養による固体機能制御と疾患 アミノ酸トランスポーターと癌2009

    • Author(s)
      金井好克
    • Journal Title

      細胞工学 28

      Pages: 789-793

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 上皮体制と病態2009

    • Author(s)
      金井好克
    • Journal Title

      腎臓 32

      Pages: 139-146

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Fanconi-Bickel症候群2009

    • Author(s)
      金井好克
    • Journal Title

      小児科診療 72

      Pages: 348-348

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Ca^<2+>-dependent induction of TRPM2 currents in hippocampal neurons.2009

    • Author(s)
      Olah ME, Jackson MF, et al.
    • Journal Title

      J.Physiol. 587

      Pages: 965-979

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in temperature preferences and energy homeostasis in dystroglycan mutants.2009

    • Author(s)
      Takeuchi K, Nakano Y, Kato U, Kaneda M, Aizu M, et al.
    • Journal Title

      Science 323

      Pages: 1740-1743

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.2009

    • Author(s)
      Kiyonaka S, Kato K, Nishida M, Mio K, Numaga T, et al.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 5400-5405

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tetrameric Orail is a teardrop-shaped molecule with a long, tapered cytoplasmic domain.2009

    • Author(s)
      Maruyama Y, Ogura T, Mio K, Kato K, Kaneko T, et al.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 13676-13685

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRPM2 functions as lysosomal Ca^<2+> release channel in β-cells.2009

    • Author(s)
      Lange I, Yamamoto Y, Partida-Sanchez S, Mori Y
    • Journal Title

      Science Signaling 2

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] STIM protein coupling in the activation of Orai channis.2009

    • Author(s)
      Wang Y, Deng X, Zhou Y, Hendron E, Mancarella S, et al
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 7391-7396

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via PLC/diacylglycerol and PLA_2/£s-hydroxylase/20-HETE pathways.2009

    • Author(s)
      Inoue R, Jensen LJ, JianZ, Shi J, Hai L, Lurie AI, et al.
    • Journal Title

      Circ Res. 104

      Pages: 1399-1409

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Targetted disruption of the voltage-dependent Ca^<2+> channel α_2/δ-1 subunit.2009

    • Author(s)
      Fuller-Bicer GA, Varadi G, Koch SE, Ishii M, et al.
    • Journal Title

      Am.J.Physiol. Heart Circ.Physiol. 297

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.2009

    • Author(s)
      Sun H-S, Jackson MF, Martin LJ, Jansen K, Teves L, et al.
    • Journal Title

      Nature Neurosci. 12

      Pages: 1300-1307

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of flubendiamide sensitivity in lepidopterous ryanodine receptor Ca^<2+> release channel.2009

    • Author(s)
      Kato K, Kiyonaka S, Sawa-guchi Y, Tohnishi M, et al.
    • Journal Title

      Biochemistry 48

      Pages: 10342-10352

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A single circularly permuted GFP sensor for inositol-1,3,4,5-tetrakisphosphate based on a split PH domain.2009

    • Author(s)
      Sakaguchi R, Endo T, Yama-moto S, Tainaka K, et al.
    • Journal Title

      Bioorg.Med.Chem. 17

      Pages: 7381-7386

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 活性化学種感応のチャネル機構の探求2009

    • Author(s)
      山本伸一郎、高橋重成、清中茂樹、森泰生
    • Journal Title

      蛋白質核酸酵素 54

      Pages: 212-223

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 酸化ストレス作動性TRPチャネルの化学生理学2009

    • Author(s)
      高橋重成、山本伸一郎、森泰生
    • Journal Title

      実験医学(病態解明に迫る活性酸素シグナルと酸化ストレス) 27

      Pages: 2494-2502

    • Related Report
      2009 Annual Research Report
  • [Journal Article] TRIPM2チャネルによる活性酸素シグナル増幅と慢性炎症の関連2009

    • Author(s)
      山本伸一郎、清水俊一、森泰生
    • Journal Title

      日本薬理学雑誌 134

      Pages: 122-126

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 脳はいま、化学の言葉でどこまで語れるか?2009

    • Author(s)
      森泰生
    • Journal Title

      化学 64

      Pages: 12-14

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 化学物質の感覚分子生物学-TRPチャネルはどのように物質を感知し脳へ伝えるか-2009

    • Author(s)
      清中茂樹、高橋重成、香西大輔、森泰生
    • Journal Title

      化学 64

      Pages: 27-33

    • Related Report
      2009 Annual Research Report
  • [Journal Article] TRPチャネルの構造と多様な機能2009

    • Author(s)
      沼田朋大、香西大輔、外
    • Journal Title

      生化学 81

      Pages: 962-984

    • Related Report
      2009 Annual Research Report
  • [Journal Article] Protein kinase Cε regulates local calcium signaling in airway smoothmuscle cells.2009

    • Author(s)
      Liu, Q.H., Zheng, Y.M., Korde, A.S., Li, et al.
    • Journal Title

      Am.J.Respir.Cell.Mol.Biol. 40

      Pages: 663-671

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3 and dysferlin.2009

    • Author(s)
      Cai, C., Weisleder, N., Ko, J-K., Komazaki, S., et al.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 15894-15902

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Essential role of TRIC-B channel in Ca^<2+>- handling of alveolar epithelium and perinatal lung maturation.2009

    • Author(s)
      Yamazaki, D., Komazaki, S., Nakanishi, H., et al.
    • Journal Title

      Development 136

      Pages: 2355-2361

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice : decreased social contact duration in two social interaction tests.2009

    • Author(s)
      Matsuo, N., Tanda, K., Nakanishi, K., et al.
    • Journal Title

      Front.Behav.Neurosci. 3

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sarcalumenin is essential for maintaining cardiac function during endurance exercise training.2009

    • Author(s)
      Jiao,Q., Bai, Y., Akaike, T., Takeshima,H., Ishikawa, Y., et al.
    • Journal Title

      Am.J.Physiol.Heart Circ.Physiol. 297

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of flubendiamide sensitivity in lepidop-terous rvanodine receptor.2009

    • Author(s)
      Kato, K., Kiyonaka, S., Sawa-guchi, Y., Tohnish, M., et al.
    • Journal Title

      Biochemistry 48

      Pages: 10342-10352

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In-vitro characterization of the six clustered variants of NPC 1L1 observed in cholesterol low absorbers.2009

    • Author(s)
      Yamanashi Y, Takada T, Suzuki H.
    • Journal Title

      Pharmacogenet Genomics 19

      Pages: 884-892

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4.2009

    • Author(s)
      Ikebuchi Y, Takada T, Ito K, Yoshikado T., et al.
    • Journal Title

      Hepatol Res 39

      Pages: 1091-1107

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vps33a Mediates RANKL Storage in Secretory Lysosomes in Osteoblastic Cells.2009

    • Author(s)
      Kariya Y, Honma M, Aoki S, Chiba A, Suzuki H.
    • Journal Title

      J Bone Miner Res 24

      Pages: 1741-1752

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Common Defects of ABCG2, a High-capacity Urate Exporter, Cause Gout : A Function-based Genetic Analysis in a Japanese Population.2009

    • Author(s)
      Matsuo H, Takada T, Ichida K, Nakamura T, Nakayama A, et al.
    • Journal Title

      Science Translational Medicine 1

      Pages: 41-48

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of 1-type amino acid transporter 1(LAT1)and 4F2 heavy chain(CD98)expression in stage I pulmonary adenocarcinoma2009

    • Author(s)
      Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, et.al.
    • Journal Title

      Lung Cancer (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Correlation of angiogenesis with(18)F-FMT and(18)F-FDG uptake in non-small cell lung cancer2009

    • Author(s)
      Kaira K, Oriuchi N, Shimizu K, Ishikita T, Higuchi T, et.al.
    • Journal Title

      Camcer Sci (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer2009

    • Author(s)
      Sakata T, Ferdous Tsuruta T, Satoh T, Baba S, Muto T, et.al.
    • Journal Title

      Pathol Int 59

      Pages: 7-18

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Posttranslational regulation of Abcc2 expression by SUMOylation system2009

    • Author(s)
      Minami S, Ito K,_Honma M, Ikebuchi Y, Anzai Y, et.al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 296

      Pages: 406-413

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of L-type amino acid transporter 1(LAT1)and 4F2 heavy chain(CD98)expression in early stage squamous cell carcinoma of the lung2009

    • Author(s)
      Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, et.al.
    • Journal Title

      Cancer Sci (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of thoracic tumors with(18)F-FMT and(18)F-FDG PET-CT : a clinicopathological study2009

    • Author(s)
      Kaira K, Oriuchi N, Shimizu K, Ishikita T, Higuchi, et.al.
    • Journal Title

      Int J Cancer 124

      Pages: 1152-1160

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] System L amino acid transporter inhibitor enhances anti-tumor activity of cisplatin in a head and neck squamous cell carcinoma cell line2009

    • Author(s)
      Yamauchi K, Sakurai H, Kimura T, Wiriyasermkul P, Nagamori S Kanai Y, Kohno N
    • Journal Title

      Cancer Lett 276

      Pages: 95-101

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel role of the C-terminus of b 0,+ AT in the ER-Golgi trafficking of the rBAT-b 0,+ AT heterodimeric amino acid transporter2009

    • Author(s)
      Sakamoto S, Chairoungdua A, Nagamori S, et.al.
    • Journal Title

      Biochem J 417

      Pages: 141-448

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 活性化学種感応のチャネル機構の探求2009

    • Author(s)
      山本伸一郎、高橋重成、清中茂樹、森泰生
    • Journal Title

      蛋白質核酸酵素 (印刷中)

    • Related Report
      2008 Annual Research Report
  • [Journal Article] MG53 nucleates assembly of cell membrane repair machinery.2009

    • Author(s)
      Cai C, Masumiya H, Weisleder N, Matsuda N, Nishi M, et.al.
    • Journal Title

      Nat Cell Biol. 11

      Pages: 56-64

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MG53 regulates membrane budding and exocytosis in muscle cells2009

    • Author(s)
      Cai C, Masumiya H, Weisleder N, Pan Z, Nishi M, et.al.
    • Journal Title

      J Biol. Chem 284

      Pages: 3314-3322

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic evidence for functional role of ryanodine receptor 1 in pulmonary artery smooth muscle cells2009

    • Author(s)
      Li XQ, Zheng YM, Rathore R, Ma J. Takeshima H., et.al.
    • Journal Title

      Pflugers Arch 457

      Pages: 771-783

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FIC1-mediated stimulation of FXR. activity is decreased with PFIC1 mutations in HepG2 cells2009

    • Author(s)
      Koh S, Takada T, Kukuu I, and Suzuki H
    • Journal Title

      J Gastroenterol (In press)

    • NAID

      10025175644

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Posttranslational regulation of Abcc2 expression by SUMOylation system2009

    • Author(s)
      Minami S, Ito K, Honma M, Ikebuchi Y, Anzai N, et.al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 296

      Pages: 406-413

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration.2008

    • Author(s)
      Y amamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, Takeshima H, Mori Y.
    • Journal Title

      Nature Med. 14

      Pages: 738-747

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Niemann-pick C1-like 1 mediates alpha-tocopherol transport.2008

    • Author(s)
      Narushima K, Takada T, Yamanashi Y, Suzuki H.
    • Journal Title

      Mol Pharmacol. 74

      Pages: 42-49

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia.2008

    • Author(s)
      Matsuo H, Chiba T, Nagamori S, Nakayama A, Domoto H, Phetdee K, Wiriyasermkul P, Kikuchi Y, Oda T, Nishiyama J, Nakamura T, Morimoto Y, Kamakura K, Sakurai Y, Nonoyama S, Kanai Y, Shinomiya N.
    • Journal Title

      Am J Hum Genet. 83

      Pages: 744-751

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters2008

    • Author(s)
      Morimoto E, Kanai Y, Kim do K, Chairoungdua A, et.al.
    • Journal Title

      J. Pharmacol Sci 108

      Pages: 505-516

    • NAID

      10025732972

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of amino acid transport system L in HTB-41 human salivary gland epidermoid carcinoma cells2008

    • Author(s)
      Park NS, Kim SG, Kim HK, Moon SY, Kim CS, Cho SH, et.al.
    • Journal Title

      Anticancer Res 28

      Pages: 2649-2655

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mutations in glucose transporter 9 gene SLC2A9 cause renal hypouricemia2008

    • Author(s)
      Matsuo H, Chiba T, Nagamori S, Nakayama A, et.al.
    • Journal Title

      Am J Hum Genet 83

      Pages: 744-751

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] L-glutamate enhances methylmercury toxicity by synergistically increasing oxidative stress2008

    • Author(s)
      Amonpatumrat S, Sakurai H, Wiriyasermkul P, et.al.
    • Journal Title

      J Pharmacol Sci 108

      Pages: 280-289

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1-type amino acid transporter 1 and CD98 expression in primary an d metastatic sites of human neoplasms2008

    • Author(s)
      Kaira K, Oriuchi N, Imai H,S himizu K, Yanagitani. N, et.al.
    • Journal Title

      Cancer Sci 99

      Pages: 2380-2386

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of placental amino acid transporter activity by mammalian target of rapamycin2008

    • Author(s)
      Roos S, Kanai Y, Prasad PD, Powell TL, Jansson T.
    • Journal Title

      Am J Physiol Cell Physiol 296

      Pages: 142-150

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] BCH, an inhibitor of system L amino acid transporters, induces apoptosis in cancer cells2008

    • Author(s)
      Kim CS, Cho SH, Chun HS, Lee SY, Endou H, Kanai, et.al.
    • Journal Title

      Biol Pharm Bull 31

      Pages: 1096-1100

    • NAID

      110006684323

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional and immunochemical characterization of a novel organic anion transporter Oat8(Slc22a9)in rat renal collecting duct2008

    • Author(s)
      Yokoyama H, Anzai N, Ljubojevic M, Ohtsu N, Sakata T, et.al.
    • Journal Title

      Cell Physiol Biochem 21

      Pages: 269-278

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of L-type amino acid transporter 1(LAT1)in neuroendocrine tumors of the lung2008

    • Author(s)
      Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, et.al.
    • Journal Title

      Pathol Res Pract 204

      Pages: 553-561

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells2008

    • Author(s)
      Kobayashi K, Ohnishi A, Promsuk J, Shimizu S, Kanai, et.al.
    • Journal Title

      Neurosurgery 62

      Pages: 503-504

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of organic anion transporters in the renal excretion of perfluorooctanoic acid2008

    • Author(s)
      Nakagawa H, Hirata T, Terada T, Jutabha P, Miura D, et.al.
    • Journal Title

      Basic Clin Pharmacol Toxicol 103

      Pages: 1-8

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アミノ酸トランスポーター : 悪性腫瘍の診断と治療の分子標的としての可能性2008

    • Author(s)
      金井好克
    • Journal Title

      遺伝子医学MOOK 12号

      Pages: 218-224

    • Related Report
      2008 Annual Research Report
  • [Journal Article] トランスポートゾーム : その概念と生体膜輸送における重要性2008

    • Author(s)
      金井好克
    • Journal Title

      遺伝子医学MOOK 12号

      Pages: 68-75

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 薬効標的のトランスポーター2008

    • Author(s)
      金井好克
    • Journal Title

      遺伝子医学MOOK 12号

      Pages: 29-34

    • Related Report
      2008 Annual Research Report
  • [Journal Article] わが国の小児科医・研究者によって新たに提唱・発見された疾患、疾患概念、原因の究明された疾患 : Hartnup病2008

    • Author(s)
      金井好克
    • Journal Title

      小児内科 40

      Pages: 1979-1984

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 調節蛋白の異常による腎疾患 : 細胞膜輸送を調節する細胞内シグナル機構とその異常による疾患2008

    • Author(s)
      金井好克
    • Journal Title

      腎臓 31

      Pages: 175-180

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 近位尿細管におけるアミノ酸輸送と代謝2008

    • Author(s)
      金井好克
    • Journal Title

      腎と透析 65

      Pages: 681-685

    • Related Report
      2008 Annual Research Report
  • [Journal Article] トランスポーター異常症と尿路結石2008

    • Author(s)
      金井好克
    • Journal Title

      腎臓 31

      Pages: 67-74

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 腫瘍細胞のアミノ酸トランスポーターの発現とそれを標的とした診断と治療への応用の可能性2008

    • Author(s)
      金井好克
    • Journal Title

      膜 33

      Pages: 108-117

    • NAID

      10021167462

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 腎尿細管における尿酸輸送の分子メカニズム尿酸トランスポーターの局在と機能2008

    • Author(s)
      金井好克
    • Journal Title

      日本臨床 66

      Pages: 659-666

    • Related Report
      2008 Annual Research Report
  • [Journal Article] アミノ酸輸送と細胞機能2008

    • Author(s)
      金井好克
    • Journal Title

      アミノ酸研究 2

      Pages: 109-120

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Characterization of a Tobacco TPK-type K^+ Channel as a Novel Tonoplast K^+ Channel Using Yeast Tonoplasts2008

    • Author(s)
      Hamamoto S, Matsuoka K, Higashihi K, Igarashi K, et.al.
    • Journal Title

      J. Biol. Chem 283

      Pages: 1991-1920

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRPM2-mediated Ca^<2+> influx induces chemokine production in monocvtes that aggravates inflammatory neutronhil infiltration2008

    • Author(s)
      Yamamoto S, Shimishu S, Kiyonaka S, Takahashi N, et.al.
    • Journal Title

      Nature Med 14

      Pages: 738-747

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two novel alleles of tottering with distinct CaV2.1 calcium channel neuropathologifes2008

    • Author(s)
      Miki T, Zwingman TA, Wakamozri M, Lutz CM, Cook SA, et.al.
    • Journal Title

      Neuroscience 155

      Pages: 31-44

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC62008

    • Author(s)
      Takahashi S, Lin H, Geshi N, Mori Y, Kawarabayashi Y, et.al.
    • Journal Title

      J. Physiol 586

      Pages: 349-354

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A CACNB4 mutation shows that altered Ca(v)2.1 function may be a genetic modifier of severe myoclonic epilepsy in infancy2008

    • Author(s)
      Ohmori I, Ouchida M, Miki T, Mimaki N, Kiyonaka S, et.al.
    • Journal Title

      Neurobiol. Dis 32

      Pages: 349-354

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of TRPA1 channel activation by cysteine-reactive inflammatory mediators2008

    • Author(s)
      Takahashi N, Mizuno Y, Kozai D, Yamamoto S, Kiyonaka, et.al.
    • Journal Title

      Channels 2

      Pages: 287-298

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ca2^<+>-dependent induction of TRPM2 currents in hippocampal neurons2008

    • Author(s)
      Dlah ME, Jackson MF, Li, et.al.
    • Journal Title

      J. Physiol (In press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 神経伝達物質放出におけるCa^<2+>チャネル複合体形成の生理的意義2008

    • Author(s)
      清中茂樹、三木崇史、瓜生幸、森泰生
    • Journal Title

      生化学 80

      Pages: 658-661

    • NAID

      10021924872

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional crosstalk between cell-surface and intracellular channels mediated by junctophilins essential for neuronal functions2008

    • Author(s)
      Kakizawa S, Moriguchi S, Ikeda A, Iino M, Takeshima H.
    • Journal Title

      Cerebellum 7

      Pages: 385-361

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration2008

    • Author(s)
      Yamamoto S, Shimizu S, Kiyonaka S. Takahashi N., et.al.
    • Journal Title

      Nat Med 14

      Pages: 738-747

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Single-channel characterization of the rabbit recombinant RyR2 reveals a novel inactivation property of physiological concentrations of ATP2008

    • Author(s)
      Stewart R, Song L, Carter SM, Sigalas C. Zaccai NR, et.al.
    • Journal Title

      J. Membr. Biol 65

      Pages: 65-77

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nociceptin-receptor deficiency prevents postherpetic pain without effects on acute herpetic pain in mice2008

    • Author(s)
      Sasaki A, Takasaki I, Andoh T, Shiraki K, Takeshima H, et.al.
    • Journal Title

      Neuroreport 19

      Pages: 83-86

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Superoxide-induced potentiation in the hippocampus requires activation of ryanodine receptor type 3 and ERK2008

    • Author(s)
      Huddleston AT, Tang W, Takeshima H, Hamilton SL, et.al.
    • Journal Title

      J. Neurophysiol 99

      Pages: 1565-1571

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ABCC2/Abcc2 transport property in different species and its modulation by heterogeneous factors2008

    • Author(s)
      Ito K, et.al.
    • Journal Title

      Drug Metab Pharmacokinet 23

      Pages: 394-405

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cholesterol but not association with detergent resistant membranes is necessary for the transport function of MRP2/ABCC22008

    • Author(s)
      Ito K, Hoekstra D, and van Ijzendoom SC., et.al.
    • Journal Title

      FEBS Lett 582

      Pages: 4153-4157

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 32008

    • Author(s)
      Kobayashi K, Ito K, Takada T, Sugiyama Y, and Suzuki H.
    • Journal Title

      Pharmacogenet Genomics 18

      Pages: 823-833

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Niemann-pick Cl-like 1 mediates alpha-tocopherol transport2008

    • Author(s)
      Narushima K, Takada T, Yamanashi Y, and Suzuki H., et.al.
    • Journal Title

      Mol Pharmacol 74

      Pages: 42-49

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information2008

    • Author(s)
      Ohno Y, Hisaka A, Ueno M, and Suzuki H.
    • Journal Title

      Clin Pharmacokinet 47

      Pages: 669-680

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differential Expression of System L Amino Acid Transporters during Wound Healing Process in the Skin of Young and Old Rats2008

    • Author(s)
      Jeong, MJ・Kim, CS・Park, JC・Kim, HJ・Ko, YM・Park, KJ, et. al.
    • Journal Title

      Biol Pharm Bull 31

      Pages: 395-399

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prognostic significance of L-type amino acid transporter I expression in resectable stage I-III nonsmall cell lung cancer.2008

    • Author(s)
      Kaira, K・Oriuchi, N・Imai, H・Shimizu, K・Yanagitani, N, et. al.
    • Journal Title

      Br J Cancer 98

      Pages: 742-748

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Membrane-Spanniing Domain of CD98 Heavy Chain Promotes {alpha}v{beta}3 Integrin Signals in Human Extravillous Trophoblasts.2008

    • Author(s)
      Kabir-Salmani, M・Fukuda, MN・Kanai-Azuma, M.・Ahmad, N, et. al.
    • Journal Title

      Mol Endocrinol 22

      Pages: 707-715

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HNF4alpha is a Crucial Modulator of the Cholesterol-Dependent Regulation of NPC1L1.2008

    • Author(s)
      Iwayanagi, Y・Takada, T・Suzuki, H.
    • Journal Title

      Pharm Res. In press

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels.2007

    • Author(s)
      Kiyonaka S, Wakamori M, Miki T, Uriu Y, Nonaka M, Bito H, Beedle AM, Mori E, Hara Y, De Waard M, Kanagawa M, Itakura M, Takahashi M, Campbell KP, Mori Y.
    • Journal Title

      Nature Neurosci. 10

      Pages: 691-701

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer : a clinicopathologic study.2007

    • Author(s)
      Kaira K, Oriuchi N, Otani Y, Shimizu K, Tanaka S, Imai H, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Dobashi K, Kanai Y, Endou H, Nakajima T, Endo K, Mori M.
    • Journal Title

      Clin Cancer Res. 13

      Pages: 6369-6378

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] TRIC channels are essential for Ca2+ handling in intracellular stores.2007

    • Author(s)
      Yazawa M, Ferrante C, Feng J, Mio K, Ogura T, Zhang M, Lin P-H, Pan Z, Komazaki S, Kato K, Nishi M, Zhao X, Weisleder N, Sato C, Ma J, Takeshima H.
    • Journal Title

      Nature. 448

      Pages: 78-82

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.2007

    • Author(s)
      Zhang M, Yamazaki T, Yazawa M, Treves S, Nishi M, Murai M, Shibata E, Zorzato F, Takeshima H.
    • Journal Title

      Cell Calcium. 42

      Pages: 83-90

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.2007

    • Author(s)
      Kakizawa S, Kishimoto Y, Hashimoto K, Miyazaki T, Furutani K, Shimizu H, Fukaya M, Nishi M, Sakagami H, Ikeda A, Kondo H, Kano M, Watanabe M, Iino M, Takeshima H.
    • Journal Title

      EMBO J. 26

      Pages: 1924-1933

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate.2007

    • Author(s)
      Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y.
    • Journal Title

      Hepatology.

      Pages: 1046-1055

    • NAID

      130005449292

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study.2007

    • Author(s)
      Kaira, K・Oriuchi, N・Otani, Y・Shimizu, K・Tanaka, S, et. al.
    • Journal Title

      Clin Cancer Res 13

      Pages: 6369-6378

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Spermatogenesis in aged rats after prenatal 3,3^1,4,4^1,5-pentachlorobiphenyl exposure.2007

    • Author(s)
      Wakui, S・Takagi, F・Muto, T・Yokoo, K・Hirono, S, et. al.
    • Journal Title

      Toxicology 238

      Pages: 186-191

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract.2007

    • Author(s)
      Nakanishi, K・Ogata, S・Matsuo, H・Kanai, Y・Endou, H, et. al.
    • Journal Title

      Virchows Arch 451

      Pages: 681-690

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gene expression profiles in T24 human bladder carcinoma cells by inhibiting an L-type amino acid transporter, LAT1.2007

    • Author(s)
      Baniasadi, S・Chairoungdua, A・Iribe, Y・Kanai, Y・Endou, H, et. al.
    • Journal Title

      Arch Pharm Res 30

      Pages: 444-445

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate.2007

    • Author(s)
      Shin, HJ・Anzai, N・Enomoto, A・He, X・Kim do, K・Endou, et. al.
    • Journal Title

      Hepatology 45

      Pages: 1046-1055

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones.2007

    • Author(s)
      Ljubojevic, M・Balen, D・Brrljak, D・Kusan, K・Anzai, N, et. al.
    • Journal Title

      Am J Physiol Renal Physiol. 292

      Pages: 361-372

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mg2+ activates the ryanodine receptor type 2 (RyR2) at intermediate Ca2+ concentrations.2007

    • Author(s)
      Chugun, A・Sato, O・Takeshima, H・Ogawa, Y
    • Journal Title

      Am J Cell Phys 292

      Pages: 535-544

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ORL1 receptor-mediated down-regulation of mRER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle.2007

    • Author(s)
      Miyakawa, K・Uchida, A・Shiraki, T・Tesjo,a, K・Takeshima, H, et. al.
    • Journal Title

      Neuropharmacol 52

      Pages: 1055-1064

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.2007

    • Author(s)
      Kakizawa, S.・Kishimoto, Y.・Hashimoto, K・Miyazaki, T・Furutani, K, et. al.
    • Journal Title

      EMBO J 26

      Pages: 1924-1933

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nociceptin receptor (NOP)-deficient mice show memory and learning enhancement in a novel KUROBOX apparatus using stress-free positive cue task.2007

    • Author(s)
      Nagai, J.・Kurokawa, M.・Takeshima, H.・Kieffer, B.・L. Ueda, H
    • Journal Title

      J. Pharmacol. Exp. Ther. 321

      Pages: 195-201

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Conformation-dependent staility of junctophilin 1(JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols.2007

    • Author(s)
      Phimister, A.J.・Lango, J.・Lee., E.H.・Ernst-Russell, M.・Takeshima, H.・Ma, J.・Allen, P.D.・Pessah, I.N
    • Journal Title

      J. Biol. Chem 282

      Pages: 8667-8677

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.2007

    • Author(s)
      Zhang, M.・Yamazaki, T.・Yazawa, M.・Treves, S.・Nishi, M.・Murai, M.・Shibata, E., et. al.
    • Journal Title

      Cell Calcium 42

      Pages: 83-90

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladdersmooth muscle.2007

    • Author(s)
      Hotta, S.・Morimura, K.・Ohya, S.・Muraki, K.・Takeshima, H.・Imaizumi, Y.
    • Journal Title

      J Physiol 582

      Pages: 489-506

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mutations of junctophilin type 2 associated with hypertrophic cardiomyopathy.2007

    • Author(s)
      Matsushita, Y.・Furukawa, T.・Kasanuki, H.・Nishibatake, M.・Kurihara, Y.・Ikeda, A., et. al.
    • Journal Title

      J Hum Genet 52

      Pages: 543-548

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRIC channels are essential for Ca2+ handling in intracellular stores.2007

    • Author(s)
      Yazawa, M.・Ferrante, C.・Feng, J.・Mio. K.・Ogura, T.・Zhang, M.・Lin, P-H.・Pan, Z.・Komazaki, S., et. al.
    • Journal Title

      Nature 448

      Pages: 78-82

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Systemic ablation of RyR3 Ca2+ spark signaling in adult skeletal muscle.2007

    • Author(s)
      Weisleder, N.・Ferrante, C.・Hirata, Y.・Collet, C.・Chu, Y.・Cheng, H.・Takeshima, H.・Ma, J
    • Journal Title

      Cell Calcium 42

      Pages: 548-555

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Augmentation of drug-induced cell death by ER protein BRI3BP.2007

    • Author(s)
      Yamazaki, T.・Sasaki, N.・Nishi, M.・Yamazaki, D.・Ikeda, et. al.
    • Journal Title

      Biochem. Biophys. Res. Commun 362

      Pages: 971-975

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.2007

    • Author(s)
      Ikeda, A.・Miyazaki, T.・Kakizawac, S.・Okuno, Y.・Tsuchiya, S., et. al.
    • Journal Title

      Biochem. Biophys. Res. Commun 363

      Pages: 835-839

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Loss of skeletal muscle strength by ablation of the sarcoplasmic reticulum protein JP45.2007

    • Author(s)
      Delbono, O.・Xia, J.・Treves, S.・Wang, Z-M., et. al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 104

      Pages: 20108-20113

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels.2007

    • Author(s)
      Kiyonaka, S・Wakamori, M・Miki, T・Uriu, Y・Nonaka, M・Bito, H・Beedle, AM・Mori, E, et. al.
    • Journal Title

      Nature Neurosci. 10

      Pages: 691-701

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas.2007

    • Author(s)
      Mio, K・Ogura, T・Kiyonaka, S・Hiroaki, Y・Tanimura, Y・Fujiyoshi, Y・Mori, Y, et. al.
    • Journal Title

      J. Mol. Biol. 367

      Pages: 373-383

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transient receptor potential (TRP) protein 7 acts as a G proteinactivated Ca2+ channel mediating angiotensin II-induced myocardial apoptosis.2007

    • Author(s)
      Satoh, S・Tanaka, H・Ueda, Y・Oyama, JI・Sugano, M・Sumimoto, H・Mori, Y・Makino, N
    • Journal Title

      Mol. Cell Biochem. 294

      Pages: 205-215

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Properties of human Cav2.1 channel with a spinocerebellar ataxia type 6 mutation expressed in Purkinje cells.2007

    • Author(s)
      Saegusa, H・Wakamori, M・Matsuda, Y・Wang, J・Mori, Y・Zong, S・Tanabe, T
    • Journal Title

      Mol. Cell. Neurosci 34

      Pages: 261-270

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Upregulation of TRPC1 in the development of cardiac hypertrophy.2007

    • Author(s)
      Ohba, T・Watanabe, H・Murakami, M・Takahashi, Y・Iino, K・Kuromitsu, S・Mori, Y・Ono, K・Iijima, T・Ito, H
    • Journal Title

      J. Mol. Cell. Cardiol. 42

      Pages: 498-507

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Myosin light chain kinase-independent inhibition by ML-9 of murine TRPC6 channels expressed in HEK293 cells.2007

    • Author(s)
      Shi, J・Takahashi, S・Jin, X-H・Ki, Y-Q・Ito, Y・Mori, Y・Inoue, R
    • Journal Title

      British J. Pharmacol. 152

      Pages: 122-131

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ga12/13-mediated upregulation of TPPC6 negatively regulates endothelin-induced cardiac myofibroblast formation and collagen synthesis through NFAT activation.2007

    • Author(s)
      Nishida, M・Onohara, N・Sato, Y・Suda, R・Ogushi, M・Tanabe, S・Inoue, R・Mori, Y・Kurose, H
    • Journal Title

      J. Biol. Chem. 282

      Pages: 23117-23128

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Solution structure of agelenin, an insecticidal peptide isolated from the spider Agelena opulenta, and its structural similaritiesto insect-specific calcium channel inhibitors.2007

    • Author(s)
      Yamaji, N・Sugase, K・Nakajima, T・Miki, T・Wakamori, M・Mori, Y・Iwashita, T
    • Journal Title

      FEBS Lett 581

      Pages: 3789-3794

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mutation associated with an autosomal dominant cone-rod dystrophy CORD7 modifies RIM1-mediated modulation of voltage-dependent Ca2+ channels.2007

    • Author(s)
      Miki, T・Kiyonaka, S・Uriu, Y・De, Waard M・Wakamori, M・Beedle, AM・Campbell, KP・Mori, Y
    • Journal Title

      Channels 1

      Pages: 144-147

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] TRPM7 a possible extracellular divalent cation sensor in hippocampal neurons.2007

    • Author(s)
      Wei, W-L・Olah, ME・Czerwinska, E・Czerwinski, W・Mori, Y・Orser, BA, et. al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 16323-16328

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Subunit dissociation of trpc3 ion channel under high-salt condition.2007

    • Author(s)
      Mio, K・Ogura, T・Kiyonaka, S・Mori, Y・Sato, C.
    • Journal Title

      J. Electron Microsc. (Tokyo) 56

      Pages: 111-117

    • NAID

      10028200220

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] General framework for the quantitative prediction of CYP3A4-mediated oral drug interactions based on the AUC increase by coadministration of standard drugs.2007

    • Author(s)
      Ohno, Y・Hisaka, A・Suzuki, H.
    • Journal Title

      Clin Pharmacokinet 46

      Pages: 681-696

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.2007

    • Author(s)
      Okada, K・Shoda, J・Kano, M・Suzuki, S・Ohtake, N・Yamamoto, M・Takahashi, H・Utsunomiya, H.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 292

      Pages: 1450-1463

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bezafibrate induces multidrug-resistance P-Glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice.2007

    • Author(s)
      Shoda, J・Okada, K・Inada, Y・Kusama, H・Utsunomiya, H・Oda, K・Yokoi, T・Yoshizato, K・Suzuki, H.
    • Journal Title

      Hepatol Res 37

      Pages: 548-556

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cholesterol-lowering effect of ezetimibe in uridine diphosphate glucuronosyltransferase 1A-deficient (Gunn) rats.2007

    • Author(s)
      Yamamoto, T・Ito, K・Honma, M・Takada, T・Suzuki, H
    • Journal Title

      Drug Metab Dispos 35

      Pages: 1455-1458

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New Insights into Renal Transport of Urate.2007

    • Author(s)
      Anzai N, et al.
    • Journal Title

      Curr Opin Rheumatol. 19

      Pages: 151-157

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Role of Mouse Organic Anion Transporter 3 (mOat3) as a Basolateral Prostaglandin E(2) Transport Pathway.2007

    • Author(s)
      Nilwarangkoon S, et al.
    • Journal Title

      J Pharmacol Sci. 103

      Pages: 48-55

    • Related Report
      2006 Annual Research Report
  • [Journal Article] LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR.2007

    • Author(s)
      Okuwaki M, et al.
    • Journal Title

      Pharm Res. 24

      Pages: 390-398

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Niemann-Pick Cl-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.2007

    • Author(s)
      Yamanashi Y, et al.
    • Journal Title

      J Pharmacol Exp Ther 320

      Pages: 559-564

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity.2006

    • Author(s)
      Noshiro R, Anzai N, Sakata T, Miyazaki H, Terada T, Shin HJ, He X, Miura D, Inui K, Kanai Y, Endou H.
    • Journal Title

      Kidney Int. 70

      Pages: 275-282

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nitric oxide activates TRP channels by cysteine S-nitrosylation.2006

    • Author(s)
      Yoshida T, Inoue R, Morii T, Takahashi N, Yamamoto S, Hara Y, Tominaga M, Shimizu S, Sato Y, Mori Y.
    • Journal Title

      Nature Chem.Biol. 2

      Pages: 596-607

    • NAID

      130007038569

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.2006

    • Author(s)
      Baba Y, Hayashi K, Fujii Y, Mizushima A, Watarai H, Wakamori M, Numaga T, Mori Y, Iino M, Hikida M, Kurosaki T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 103

      Pages: 16704-16709

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006

    • Author(s)
      Shigeta Y, Kanai Y, Chairoungdua A, Ahmed N, Sakamoto S, Matsuo H, Kim DK, Fujimura M, Anzai N, Mizoguchi K, Ueda T, Akakura K, Ichikawa T, Ito H, Endou H.
    • Journal Title

      Kidney Int. 69

      Pages: 1198-1206

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Muscle aging is associated with compromised Ca2+ spark signaling and segregated intracellular Ca2+ release.2006

    • Author(s)
      Weisleder N, Brotto M, Komazaki S, Pan Z, Zhao X, Nosek T, Parness J, Takeshima H, Ma J.
    • Journal Title

      J.Cell Biol. 174

      Pages: 639-645

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins.2006

    • Author(s)
      Moriguchi S, Nishi M, Komazaki S, Sakagami H, Miyazaki T, Masumiya H, Saito S, Watanabe M, Kondo H, Yawo H, Fukunaga K, Takeshima H.
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 103

      Pages: 10811-10816

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impaired cerebellar functions in mutant mice lacking DNER.2006

    • Author(s)
      Togho A, Eiraku M, Miyazaki T, Miura E, Kawaguchi S, Nishi M, Watanabe M, Hirano T, Kengaku M, Takeshima H.
    • Journal Title

      Mol.Cell.Neurosci. 31

      Pages: 326-333

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006

    • Author(s)
      Shigeta Y, et al.
    • Journal Title

      Kidney Int. 69

      Pages: 1198-1206

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity.2006

    • Author(s)
      Noshiro R, et al.
    • Journal Title

      Kidney Int. 70

      Pages: 275-282

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Organic anion transporter family : current knowledge.2006

    • Author(s)
      Anzai N, et al.
    • Journal Title

      Pharmacol Sci. 100

      Pages: 411-426

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Renal elimination of p-aminohippurate (PAH) in respose to three days of biliary obstruction in the rat. The role of OAT1 and OAT3.2006

    • Author(s)
      Brandoni A, et al.
    • Journal Title

      Biochim Biophys Acta. 1762

      Pages: 673-682

    • Related Report
      2006 Annual Research Report
  • [Journal Article] L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors.2006

    • Author(s)
      Nawashiro H, et al.
    • Journal Title

      Int. J. Cancer 119

      Pages: 484-492

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Differential expression and functional characterization of system L amino acid transporters in human normal osteoblast cells and osteogenic sarcoma cells.2006

    • Author(s)
      Kim SG, et al.
    • Journal Title

      Anticancer Res. 26(3A)

      Pages: 1989-1996

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Expression of amino acid transporter LAT1 and 4F2hc in the healing process after the implantation of a tooth ash and plaster of Paris mixture.2006

    • Author(s)
      Kim SG, et al.
    • Journal Title

      In Vivo. 20

      Pages: 591-597

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity.2006

    • Author(s)
      Kim CH, et al.
    • Journal Title

      Anticancer Res. 26

      Pages: 2943-2948

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Localization of Ang-l, -2, Tie-2, and VEGF expression at endothelial-pericyte interdigitation in rat angiogenesis.2006

    • Author(s)
      Wakui S, et al.
    • Journal Title

      Lab Invest. 86

      Pages: 1172-1184

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Ca^<2+>/calmodulin dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK-cells.2006

    • Author(s)
      Shimizu S et al.
    • Journal Title

      J. Physiol. 570

      Pages: 219-235

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Phoneutria nigriventer ω-Phonetoxin IIA : A new tool for anti-calcium channel autoantibody assays in Lambert-Eaton myasthenic syndrome.2006

    • Author(s)
      Martin-Moutot N, et al.
    • Journal Title

      Neurobiol. Dis. 22

      Pages: 57-63

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A functional AMPA receptor-calcium channel complex in the postsynaptic membrane.2006

    • Author(s)
      Kang, MG, et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 5561-5566

    • Related Report
      2006 Annual Research Report
  • [Journal Article] TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion.2006

    • Author(s)
      Togashi K, et al.
    • Journal Title

      EMBO J. 25

      Pages: 1804-1815

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cyclosporin and Timothy syndrome increase mode 2 gating of Cav1.2 calcium channels through aberrant phosphorylation of S6 helices.2006

    • Author(s)
      Erxleben C., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A. 103

      Pages: 3932-3937

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Intracellular-produced hydroxyl radical mediates H_2O_2-induced TRPM2 channel activation and cell death in rat □-cell line RIN-5F.2006

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Cell Calcium 39

      Pages: 487-494

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A critical role of TRPM2 in neuronal cell death by hydrogen peroxide2006

    • Author(s)
      Kaneko S, et al.
    • Journal Title

      J Pharmacol. Sci. 101

      Pages: 66-76

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Blocker-resistant presynaptic voltage-dependent Ca^<2+> channels underlying glutamate release im mice nucleus tractus solitarii2006

    • Author(s)
      Yamazaki K, et al.
    • Journal Title

      Brain Res. 1104

      Pages: 103-113

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Extracellular-added ADP-ribose increases intracellular free Ca^<2+> concentration through Ca^<2+> release from stores but not through TRPM2-mediated Ca^<2+> entry, in rat β-Cell line RIN-5F.2006

    • Author(s)
      Ishii M, et al.
    • Journal Title

      J Pharmacol. Sci. 101

      Pages: 174-178

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Native TRPC7 channel activation by an inositol trisphosphate receptor-dependent mechanism.2006

    • Author(s)
      Vazquez G, et al.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 25250-25258

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Arachidonic acid can function as a signal modulator by activating the TI cation channel in taste receptor cells.2006

    • Author(s)
      Oike H, et al.
    • Journal Title

      Biochim. Biophys. Acta. 1761

      Pages: 1078-1084

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Nitric oxide activates TRP channels by cysteine S-nitrosylation2006

    • Author(s)
      Yoshida T, et al.
    • Journal Title

      Nature Chem. Biol. 2

      Pages: 596-607

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Coupling of STIM1 to store-operated Ca^<2+> entry through its constitutive and inducible movement in the endoplasmic reticulum.2006

    • Author(s)
      Baba Y, et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 16704-16709

    • Related Report
      2006 Annual Research Report
  • [Journal Article] TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.2006

    • Author(s)
      Onohara N, et al.
    • Journal Title

      EMBO J. 25

      Pages: 5305-5316

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Muscle aging is associated with compromised Ca2+ spark signaling and segregated intracellular Ca2+ release.2006

    • Author(s)
      Weisleder, N, et al.
    • Journal Title

      J. Cell Biol. 174

      Pages: 639-645

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Efflux mechanism of taurocholate across the rat intestinal basolateral membrane.2006

    • Author(s)
      Sakamoto S, et al.
    • Journal Title

      Mol Pharm. 3

      Pages: 275-281

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.2006

    • Author(s)
      Mita S, et al.
    • Journal Title

      Drug Metab Dispos 34

      Pages: 1575-1581

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area.2006

    • Author(s)
      Tsuji K
    • Journal Title

      Cancer Res 66

      Pages: 303-306

    • Related Report
      2005 Annual Research Report
  • [Journal Article] LAT1 expression in normal lung and in atypical adenomatous hyperplasia and adenocarcinoma of the lung.2006

    • Author(s)
      Nakanishi K
    • Journal Title

      Virchows Arch 448

      Pages: 142-150

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Prenatal 3,3',4,4',5-pentachlorobiphenyl exposure modulates induction of rat hepatic CYP 1A1,1B1, and AhR by 7,12-dimethylbenz[a]anthracene.2006

    • Author(s)
      Wakui S
    • Journal Title

      Toxicol Appl Pharmacol 210

      Pages: 200-211

    • Related Report
      2005 Annual Research Report
  • [Journal Article] アミノ酸トランスポーター2006

    • Author(s)
      金井 好克
    • Journal Title

      Medical Tribune 39(2)

      Pages: 34-34

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 有機カチオン/アニオントランスポーター2006

    • Author(s)
      金井 好克
    • Journal Title

      分子腎臓病学-分子生物学的アプローチと分子病態生理学-(日本臨牀2006年増刊号) 2006年増刊号

      Pages: 169-175

    • Related Report
      2005 Annual Research Report
  • [Journal Article] アミノ酸輸送体と疾患2006

    • Author(s)
      金井 好克
    • Journal Title

      医学のあゆみ 216

      Pages: 692-698

    • Related Report
      2005 Annual Research Report
  • [Journal Article] アミノ酸トランスポーター2006

    • Author(s)
      金井 好克
    • Journal Title

      細胞工学 25

      Pages: 280-286

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Ca^<2+>/calmodulin dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK cells.2006

    • Author(s)
      Shimizu S, Yoshida T, Wakamori M, Ishii M, Okada T, Takahashi M, Seto M, Sakurada K, Kiuchi Y, Mori Y
    • Journal Title

      J.Physiol. 570

      Pages: 219-235

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005

    • Author(s)
      Miyazaki H, Anzai N, Ekaratonawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, Xin H, Nonotuchi H, Tomita K, Kanai Y, Endou H.
    • Journal Title

      J.Am.Soc Nephol. 16

      Pages: 3498-3506

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impaired Ca2+ store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice.2005

    • Author(s)
      Yoshida M, Minamisawa S, Komazaki S, Shimura M, Kume H, Zhang M, Matsumura K, Nishi M, Saito M, Ishikawa Y, Yanagisawa T, Takeshima H.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 3500-3506

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule.2005

    • Author(s)
      Park SY
    • Journal Title

      Arch Parm Res 28(4)

      Pages: 421-432

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Amino acid transport system L is differently expressed in human normal oral keratinocytes and human oral cancer cells2005

    • Author(s)
      Yoon JH
    • Journal Title

      Cancer Lett. 222

      Pages: 237-245

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Integrated physiology and proximal tubular organic anion transport.2005

    • Author(s)
      Anzai N
    • Journal Title

      Curr Opin Nephrol Hypertens 14

      Pages: 472-479

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Functional Characterization of rat organic anion transporter 5 (Slc 22a19) at the apical membrane of renal proximal tubules.2005

    • Author(s)
      Anzai N
    • Journal Title

      J Pharmacol Exp Ther 315

      Pages: 534-544

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005

    • Author(s)
      Miyazaki H
    • Journal Title

      J.Am.Soc Nephol 16

      Pages: 3498-3506

    • Related Report
      2005 Annual Research Report
  • [Journal Article] CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl.2005

    • Author(s)
      Wakui S
    • Journal Title

      Toxicology 211

      Pages: 231-241

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction.2005

    • Author(s)
      Villar SR
    • Journal Title

      Kidney Int. 68

      Pages: 2704-2713

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Renal urate handling : clinical relevance of recent advances.2005

    • Author(s)
      Anzai N
    • Journal Title

      Curr Rheumatol Rep. 7

      Pages: 227-234

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Altered renal elimination of organic anions in rats with chronic renal failure.2005

    • Author(s)
      Monica Torres A
    • Journal Title

      Biochim Biophys Acta 1740

      Pages: 29-37

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Glucose transpoter2 (GLUT2)2005

    • Author(s)
      金井 好克
    • Journal Title

      腎と透析 59

      Pages: 582-584

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Urate transporter1 (URAT1)2005

    • Author(s)
      金井 好克
    • Journal Title

      腎と透析 59

      Pages: 586-588

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 腎尿細管のトランスポーター:疾患から機能へのアプローチ2005

    • Author(s)
      金井 好克
    • Journal Title

      日本尿路結石症学会誌 4(2)

      Pages: 1-17

    • Related Report
      2005 Annual Research Report
  • [Journal Article] FPL-64176 modification of CaV1.2 L-type calcium channels : dissociation of effects on ionic current and gating current.2005

    • Author(s)
      McDonough SI, Mori Y, Bean BP
    • Journal Title

      Biophys.J. 81

      Pages: 211-223

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Comprehensive analysis of the ascidian genome reveals novels insights into the molecular evolution of ion channel genes2005

    • Author(s)
      Mori Y et al.
    • Journal Title

      Physiological Genomics 222

      Pages: 269-282

    • Related Report
      2005 Annual Research Report
  • [Journal Article] selective cation permeable channel TRPC3 is a tetrahedron with a cap in the large cytoplasmic end2005

    • Author(s)
      Mio K, Ogura T, Hara Y, Mori Y, Sato C The non
    • Journal Title

      Biochem.Biophys.Res.Comm. 333

      Pages: 768-777

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The non-selective cation permeable channel TRPC3 is a tetrahedron with a cap in the large cytoplasmic end2005

    • Author(s)
      Mio K, Ogura T, Hara Y, Mori Y, Sato C
    • Journal Title

      Biochem.Biophys.Res.Comm. 333

      Pages: 768-777

    • Related Report
      2005 Annual Research Report
  • [Journal Article] The role of canonical transient receptor potential 7 (TRPC7) in B-cell receptor-activated channels.2005

    • Author(s)
      Lievremont J-P, Numaga T, Vazquez G, Lemonnier L, Hara Y, Mori E, Trebak M, Trebak M, Moss SE, Bird GS, Mori Y, Putney Jr JW
    • Journal Title

      J.Biol.Chem. 280

      Pages: 35346-35351

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Methamphetamine sensitization in nociceptin receptor knockout mice : locomotor and c-fos expression.2005

    • Author(s)
      Okabe ほか3名
    • Journal Title

      Eur.J.Pharmacol. 507

      Pages: 57-67

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Impaired Ca^<2+> store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice.2005

    • Author(s)
      Yoshida ほか11名
    • Journal Title

      J.Biol.Chem. 280

      Pages: 3500-3506

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells.2005

    • Author(s)
      Matsuya ほか11名
    • Journal Title

      J.Neurochem. 93

      Pages: 674-685

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Enhanced hippocampal acetylcholine release in nociceptin receptor knockout mice.2005

    • Author(s)
      Umezu ほか9名
    • Journal Title

      Brain Res. 1050

      Pages: 118-123

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation.2005

    • Author(s)
      Taverna ほか9名
    • Journal Title

      J.Physiol. 565

      Pages: 579-591

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Enhanced resistance to fatigue and altered calcium handling properties of sarcalumenin knockout mice.2005

    • Author(s)
      Zhao ほか8名
    • Journal Title

      Physiol.Genomics 23

      Pages: 72-78

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Regulation of the cell surface expression of human BCRP/ABCG2 by the phosphorylation state of Akt in polarized cells.2005

    • Author(s)
      Takada T., Suzuki H., Gotoh Y.Sugiyama Y.
    • Journal Title

      Drug Metab.Dispos 33

      Pages: 905-909

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11.2005

    • Author(s)
      Hayashi H., Takada T., Suzuki H., Akita H., Sugiyama Y.
    • Journal Title

      Hepatology. 41

      Pages: 916-924

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Characterization of polarized expression of point- or deletion-mutated human BCRP/ABCG2 in LLC-PK1 cells.2005

    • Author(s)
      Takada T., Suzuki H., Sugiyama Y.
    • Journal Title

      Pharm.Res. 22

      Pages: 458-464

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate : A comparison of human BSEP with rat Bsep.2005

    • Author(s)
      Hayashi H., Takada T., Suzuki H., Onuki R., Hofmann AF., Sugiyama Y.
    • Journal Title

      Biochim.Biophys.Acta 1738

      Pages: 54-62

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Impaired expression of hepatic multidrug resistance protein 2 is associated with posthepatectomy hyperbilirubinemia in patients with biliary cancer.2005

    • Author(s)
      Yamada T., Arai T., Nagino M., Oda K., Shoda J., Suzuki H., Sugiyama Y., Nimura Y.
    • Journal Title

      Langenbecks Arch.Surg 390

      Pages: 421-429

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.2005

    • Author(s)
      Matsushima S., Maeda K., Kondo C., Hirano M., Sasaki M., Suzuki H., Sugiyama Y.
    • Journal Title

      J.Pharmacol.Exp.Ther. 314

      Pages: 1059-1067

    • Related Report
      2005 Annual Research Report
  • [Journal Article] reatment of hyperbilirubinemia in Eisai hyperbilirubinemic rat by transfecting human MRP2/ABCC2 gene.2005

    • Author(s)
      Hirouchi M., Suzuki H., Sugiyama Y.
    • Journal Title

      Pharm.Res. 22

      Pages: 661-666

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Lack of improvement of oral absorption of ME3277 by prodrug formation is ascribed to the intestinal efflux mediated by breast cancer resistant protein (BCRP/ABCG2).2005

    • Author(s)
      Kondo C., Onuki R., Kusuhara H., Suzuki H., Suzuki M., Okudaira N., Kojima M., Ishiwata K., Jonker JW., Sugiyama Y.
    • Journal Title

      Pharm.Res. 22

      Pages: 613-618

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen.2005

    • Author(s)
      Adachi Y., Suzuki H., Schinkel AH., Sugiyama Y.
    • Journal Title

      Mol.Pharmacol. 67

      Pages: 923-928

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.2005

    • Author(s)
      Kobayashi D., Ieiri I., Hirota T., Takane H., Maegawa S., Kigawa J., Suzuki H., Nanba E., Oshimura M., Terakawa N., Otsubo K., Mine K., Sugiyama Y.
    • Journal Title

      Drug Metab.Dispos. 33

      Pages: 94-101

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.2005

    • Author(s)
      Mita S., Suzuki H., Akita H., Stieger B., Meier PJ, Hofmann AF., Sugiyama Y.
    • Journal Title

      Am.J.Physiol.Gastrointest.Liver Physiol. 288

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport.2005

    • Author(s)
      Ito K., Suzuki H., Horie T., Sugiyama Y.
    • Journal Title

      Pharm.Res. 22

      Pages: 1559-1577

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Sodium-dependent phosphate cotransporter type 1 (NPT1) sequence polymorphisms in male patients with gout.

    • Author(s)
      Urano W, Taniguchi A, Anzai N, Inoue E, Kanai Y, et al.
    • Journal Title

      Ann Rheum Dis.(電子版) (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular mechanisms of membrane transport of vitamin E.

    • Author(s)
      Takada T, Suzuki H.
    • Journal Title

      Mol Nutr Food Res. (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells.

    • Author(s)
      Kobayashi K, et al.
    • Journal Title

      Neurosurgery (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Oligo-Asp Tag/Zn(II)-complex probe as a new pair for labeling and fluorescence imaging of proteins

    • Author(s)
      Ojida A, et al.
    • Journal Title

      J. Am. Chem. Soc. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Trasient receptor potential (TRP) protein 7 acts as a G protein-activated Ca^<2+> channel mediating angiotensin II-induced myocardial apoptosis.

    • Author(s)
      Satoh S, et al.
    • Journal Title

      Mol. Cell Biochem. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas.

    • Author(s)
      Mio K, et al.
    • Journal Title

      J Mol. Biol. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] RIM1 confers sustained ctivity and neurotransmitter vesicle anchoring to presynaptic Ca^<2+> channels

    • Author(s)
      Kiyonaka S, et al.
    • Journal Title

      Nature Neurosci. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.

    • Author(s)
      Zhang, M, et al.
    • Journal Title

      Cell Calcium (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.

    • Author(s)
      Kakizawa, S, et al.
    • Journal Title

      EMBO J. (in press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Inchinkoto, an Herbal Medicine and Its Ingredients Dually Exerts Mrp2/MRP2-Mediated Choleresis and Nrf2-Mediated Antioxidative Action in Rat Livers.

    • Author(s)
      Okada K, et al.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol. (In press)

    • Related Report
      2006 Annual Research Report
  • [Presentation] トランスポートソームと上皮輸送2011

    • Author(s)
      金井好克
    • Organizer
      日本薬学会第131年会シンポジウム「物質透過を支配する生体バリアとしての上皮の組織構築と機能」
    • Place of Presentation
      静岡市(招待講演)
    • Year and Date
      2011-03-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] レドックス感受性TRPチャネル2010

    • Author(s)
      森泰生
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] アミノ酸トランスポーター:機能と病態2010

    • Author(s)
      金井好克
    • Organizer
      第11回日本毒性病理学会教育セミナー
    • Place of Presentation
      大阪市(招待講演)
    • Year and Date
      2010-11-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] Transporters in medical and pharmaceutical sciences2010

    • Author(s)
      金井好克
    • Organizer
      Lecture in Tianjin University of Traditional Chinese Medicine
    • Place of Presentation
      Tianjin, China(招待講演)
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] New aspects of organic anion and drug transporters of SLC22 family2010

    • Author(s)
      金井好克
    • Organizer
      2010 Shanghai ISSX/CSSX Workshop
    • Place of Presentation
      Shanghai China(招待講演)
    • Year and Date
      2010-10-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Posttraslational regulation of Abcc2 through sumoylation.2010

    • Author(s)
      Suzuki H, Sekine S, Horie T, Ito K.
    • Organizer
      Falk Symposium 175 : XXI International Bile Acid Meeting
    • Place of Presentation
      Freiburg, Germany(招待講演)
    • Year and Date
      2010-10-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] アミノ酸・有機酸の膜輸送-分子から生体へ-2010

    • Author(s)
      金井好克
    • Organizer
      金沢大学薬学シンポジウム 2010-創薬動態フォーラムin金沢-
    • Place of Presentation
      金沢(招待講演)
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 栄養学におけるトランスポーター研究の進歩2010

    • Author(s)
      金井好克
    • Organizer
      第64回日本栄養・食糧学会教育講演
    • Place of Presentation
      徳島市(招待講演)
    • Year and Date
      2010-05-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 尿酸輸送体の同定と機能解析2010

    • Author(s)
      金井好克
    • Organizer
      第1回佐賀尿酸研究会
    • Place of Presentation
      佐賀市(招待講演)
    • Year and Date
      2010-04-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] トランスポーター研究:辿ってきた道とこれから歩む道2010

    • Author(s)
      金井好克
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 有機溶質トランスポートソーム:その構築と機能的意義2010

    • Author(s)
      金井好克
    • Organizer
      特定領域研究公開シンポジウム「生体膜トランスポートソームの分子構築と生理機能」
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-19
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 腎皮質局所プロスタグランジンクリアランスにおける新規腎特異プロスタグランジントランスポーターの役割シンポジウム「シグナル分子トランスポーターの新たな展開」2010

    • Author(s)
      金井好克
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 芳香族アミノ酸誘導体の抗腫瘍効果の確立2010

    • Author(s)
      金井好克
    • Organizer
      第11回未来医療交流会
    • Place of Presentation
      大阪
    • Year and Date
      2010-01-12
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] 新規腎特異プロスタグランジントランスポーターOAT-PGの生理機能と代謝酵素15-hydroxyprostaglandin dehydrogenaseとの共役機構2009

    • Author(s)
      金井好克
    • Organizer
      脂質メディエーターワークショップ
    • Place of Presentation
      滋賀
    • Year and Date
      2009-12-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] アミノ酸トランスポーターの機能と病態-悪性腫瘍の診断と治療の分子標的としての可能性-2009

    • Author(s)
      金井好克
    • Organizer
      第9回「アミノ酸セミナー」
    • Place of Presentation
      東京
    • Year and Date
      2009-12-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] A cholesterol transporter NPC1L1 is transcriptionally and post-transcriptionally regulated by fatty acid-related factors.2009

    • Author(s)
      高田龍平, 中村英寛, 岩柳有起, 山梨義英, 鈴木洋史
    • Organizer
      第31回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metabolomics reveals in vivo functions of transporters2009

    • Author(s)
      金井好克
    • Organizer
      24th JSSX Annual Meeting in Kyoto
    • Place of Presentation
      京都
    • Year and Date
      2009-11-29
    • Related Report
      2009 Final Research Report
  • [Presentation] Metabolomics reveals in vivo functions of transporter2009

    • Author(s)
      金井好克
    • Organizer
      24^<th> JSSX Annual Meeting in Kyoto
    • Place of Presentation
      京都
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] 世界初の主要な痛風遺伝子の発見2009

    • Author(s)
      松尾洋孝, 高田龍平, 市田公美, 鈴木洋史
    • Organizer
      Science Translational Medicine創刊記念講演会
    • Place of Presentation
      横浜
    • Year and Date
      2009-11-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 胆汁脂質輸送体発現系を用いた薬物誘発性胆汁うっ滞のメカニズム解析2009

    • Author(s)
      吉門崇, 高田龍平, 山本武人, 山道寛子, 鈴木洋史, 外
    • Organizer
      第31回胆汁酸研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウルソデオキシコール酸による胆管形態変化2009

    • Author(s)
      清水秀俊, 伊藤晃成, 鈴木洋史
    • Organizer
      第31回胆汁酸研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] メタボロミクスによるトランスポーターの解析2009

    • Author(s)
      金井好克, 曽我朋義
    • Organizer
      第82回日本生化学会大会シンポジウム「メタボロミクスが切り拓くヒトシステム生物学」
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-23
    • Related Report
      2009 Final Research Report
  • [Presentation] メタボロミクスによるトランスポーターの解析 シンポジウム「メタボロミクスが切り拓くヒトシステム生物学」2009

    • Author(s)
      金井好克、曽我朋義
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Transcriptional regulation of NPC1L1 by nuclear receptors.2009

    • Author(s)
      Takada T, Iwayanagi Y, Suzuki H.
    • Organizer
      Asian Federation for Pharmaceutical Sciences 2009
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Amino acid transporters in cancer : relevance to its diagnosis and therapeutics2009

    • Author(s)
      金井好克
    • Organizer
      19th International Congress of Nutrition (ICN) Satellite Symposium "Advanced Knowledges of Amino Acid Research in Human Health and Disease"
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2009-10-04
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] トランスポーターと創薬2009

    • Author(s)
      金井好克
    • Organizer
      創薬薬理フォーラム 第17回シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-09-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] Metabolomics approaches to orphan transporters2009

    • Author(s)
      金井好克
    • Organizer
      Biomedical Transporters 2009 : Membrane transporters and impact on drug discover
    • Place of Presentation
      Thun, Switzerland
    • Year and Date
      2009-08-12
    • Related Report
      2009 Final Research Report
  • [Presentation] Metabolomics approaches to orphan transporters2009

    • Author(s)
      金井好克
    • Organizer
      Biomedical Transporters 2009 : Membrane transporters and impact on drug discovery
    • Place of Presentation
      Thun, Switzerland
    • Year and Date
      2009-08-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Novel organic anion transporters and new aspects of organic anion transport in renal proximal tubules2009

    • Author(s)
      金井好克
    • Organizer
      40th NIPS International Symposium-International Joint Symposium "Physiology of Anion Transport and Cell Volume Regulation (PAT- CVR 2009)"
    • Place of Presentation
      岡崎
    • Year and Date
      2009-08-06
    • Related Report
      2009 Final Research Report
  • [Presentation] Novel organic anion transporters and new aspects of organicanion transport in renal proximal tubules2009

    • Author(s)
      金井好克
    • Organizer
      40th NIPS International Symposium-International Joint Symposium "Physiology of Anion Transport and Cell Volume Regulation (PAT- CVR 2009)"
    • Place of Presentation
      岡崎
    • Year and Date
      2009-08-06
    • Related Report
      2009 Annual Research Report
  • [Presentation] Transportsomes in Epithelial Function, XXXVIth International Union of Physiological Sciences.2009

    • Author(s)
      金井好克
    • Organizer
      Satellite Symposium "Ion Channels : function, structure, and physiology"
    • Place of Presentation
      京都
    • Year and Date
      2009-08-04
    • Related Report
      2009 Final Research Report
  • [Presentation] ost-transcriptional regulation of biliary transporter.2009

    • Author(s)
      ItoK, Takada T, Suzuki H.
    • Organizer
      IUPS2009 satellite symposium "Ion channels and membrane transport systems : function, structure and physiology"
    • Place of Presentation
      東京
    • Year and Date
      2009-08-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] TRANSPORTSOME IN RENAL ORGANIC SOLUTE TRANSPORT XXXVIth International Union of Physiological Sciences.2009

    • Author(s)
      金井好克
    • Organizer
      Whole day symposium "Epithelial transport : bridges between molecules and function"
    • Place of Presentation
      京都
    • Year and Date
      2009-07-30
    • Related Report
      2009 Final Research Report
  • [Presentation] Transportsome in Renal Organic Solute Transport Whole day symposium "Epithelial transport : bridges between molecules and function"2009

    • Author(s)
      金井好克
    • Organizer
      XXXVIth International Union of Physiological Sciences
    • Place of Presentation
      京都
    • Year and Date
      2009-07-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Transportsomes in Epithelial Function2009

    • Author(s)
      金井好克
    • Organizer
      XXXVIth International Union of Physiological Sciences Satellite Symposium "Ion Channels : function, structure, and physiology"
    • Place of Presentation
      京都
    • Year and Date
      2009-07-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] Immuno-proteomic approach to E-C coupling : junctophilin and TRIC channel in cardiac Ca2+ release2009

    • Author(s)
      Takeshima H.
    • Organizer
      IUPS Whole-day Symposium.
    • Place of Presentation
      Kyoto.
    • Year and Date
      2009-07-28
    • Related Report
      2009 Final Research Report
  • [Presentation] Vitamin E Transport by a Cholestero Importer NPC1L1.2009

    • Author(s)
      Takada T, Narushima K, Yamanashi Y, Suzuki H.
    • Organizer
      International Union of Physiological Sciences (IUPS2009)
    • Place of Presentation
      東京
    • Year and Date
      2009-07-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification of USP14 as a regulatory factor of bile salt export pump.2009

    • Author(s)
      Ito K, Yamaji H, Takada T, Anzai N, Suzuki H., et al.
    • Organizer
      International Union of Physiological Sciences (IUPS2009)
    • Place of Presentation
      東京
    • Year and Date
      2009-07-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] アミノ酸トランスポーター:悪性腫瘍の診断と治療の分子標的としての可能性2009

    • Author(s)
      金井好克
    • Organizer
      第2回日Bimonthly symposiumトランスポーターシンポジウム「トランスポーター研究の新たな展開-トランスポーターを標的とした創薬への動向-」
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional analysis of NPC1L1, acholesterol transporter. The2009

    • Author(s)
      鈴木洋史
    • Organizer
      The 5th Takeda Scicence Foundation Symposium on Pharm Sciences.
    • Place of Presentation
      東京
    • Year and Date
      2009-05-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] アミノ酸トランスポーターと細胞機能2009

    • Author(s)
      金井好克
    • Organizer
      第63回日本栄養・食糧学会大会、シンポジウム「アミノ酸の新しい機能とこれからの展開」
    • Place of Presentation
      長崎
    • Year and Date
      2009-05-22
    • Related Report
      2009 Final Research Report
  • [Presentation] アミノ酸トランスポーターと細胞機能 シンポジウム「アミノ酸の新しい機能とこれからの展開」2009

    • Author(s)
      金井好克
    • Organizer
      第63回日本栄養・食糧学会大会
    • Place of Presentation
      長崎
    • Year and Date
      2009-05-22
    • Related Report
      2009 Annual Research Report
  • [Presentation] RACK1による抗癌剤排出輸送体BCRP/ABCG2の発現制御2009

    • Author(s)
      池淵祐樹, 伊藤晃成, 鈴木洋史, 外
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 臨床で観察される薬物誘発性肝障害の解析(3):胆汁形成阻害を介したイトラコナゾール誘発性肝障害2009

    • Author(s)
      吉門崇, 高田龍平, 山本武人, 鈴木洋史, 外
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] Ca2+チャネルシグナルソームの分子構成と生理機能2008

    • Author(s)
      森泰生
    • Organizer
      特定領域研究「生体超分子構造」第5回公開シンポジウム
    • Place of Presentation
      つくば市
    • Year and Date
      2008-12-19
    • Related Report
      2009 Final Research Report
  • [Presentation] Functional analysis of ABCB4 and its mutants in vitro2008

    • Author(s)
      Suzuki H, Yoshikado T, Ito K, Takada T.
    • Organizer
      2nd FEBS Special Meeting ABC2008
    • Place of Presentation
      Innsbruck, Austria.
    • Related Report
      2009 Final Research Report
  • [Presentation] 特定領域トランスポートソーム2006

    • Author(s)
      金井好克
    • Organizer
      第1回トランスポーター研究会
    • Place of Presentation
      東京 特別講演
    • Year and Date
      2006-12-16
    • Related Report
      2009 Final Research Report
  • [Presentation] Ryanodine receptor-mediated Ca2+ release from muscle sarcoplasmic reticulum2006

    • Author(s)
      Takeshima H.
    • Organizer
      Gordon Research Conference ; Muscle Excitation-Contraction Coupling.
    • Place of Presentation
      New London, USA.
    • Year and Date
      2006-06-09
    • Related Report
      2009 Final Research Report
  • [Book] Transient Receptor Potential Channels, Receptor Signaling Integration by TRP Channelsomes2011

    • Author(s)
      Mori Y, Kajimoto T, Nakao A, Takahashi N, Kiyonaka S.
    • Publisher
      Springer
    • Related Report
      2009 Final Research Report
  • [Book] 遺伝子医学MOOK 最新トランスポーター研究(編集、分担執筆)12号2009

    • Author(s)
      金井好克
    • Related Report
      2009 Final Research Report
  • [Book] 薬物トランスポーター 活用ライブラリー(分担執筆、乾賢一編)2009

    • Author(s)
      金井好克
    • Total Pages
      245
    • Publisher
      羊土社
    • Related Report
      2009 Annual Research Report
  • [Book] Annual Review腎臓 2009「腎尿細管におけるMg^<2+>輸送」2009

    • Author(s)
      金井好克
    • Total Pages
      288
    • Publisher
      中外医学社
    • Related Report
      2008 Annual Research Report
  • [Book] トランスポーター科学最前線(アミノ酸トランスポーター:過去、現在、そして未来へ)(分担執筆)2008

    • Author(s)
      金井好克
    • Publisher
      京都廣川書店
    • Related Report
      2009 Final Research Report
  • [Book] Annual Review 2007 腎臓、中外医学社、2007, p.42-492007

    • Author(s)
      平田 拓
    • Total Pages
      8
    • Publisher
      腎におけるプロスタグランジンシグナリングの新展開
    • Related Report
      2006 Annual Research Report
  • [Book] イオンチャネル最前線(医学のあゆみ別冊)2005

    • Author(s)
      竹島 浩
    • Publisher
      共立出版
    • Related Report
      2005 Annual Research Report
  • [Book] トランスポートソームの世界-総論 トランスポートソームの世界-膜輸送研究の源流から未来まで-

    • Author(s)
      金井好克
    • Publisher
      京都廣川書店(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Book] 栄養と代謝物のトランスポーター-総論 トランスポートソームの世界-膜輸送研究の源流から未来まで-

    • Author(s)
      金井好克
    • Publisher
      京都廣川書店(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Book] 序論 トランスポーターとトランスポートソーム、遺伝子医学MOOK19号トランスポートソーム:生体膜輸送機構の全体像に迫る-基礎、臨床・創薬応用研究の最新成果

    • Author(s)
      金井好克
    • Publisher
      メディカル ドゥ(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Book] メタボローム解析によるオルファントランスポーターの機能解析、遺伝子医学MOOK19号トランスポートソーム:生体膜輸送機構の全体像に迫る-基礎、臨床・創薬応用研究の最新成果

    • Author(s)
      金井好克
    • Publisher
      メディカル ドゥ(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Book] トランスポートソームの実体とその機能的意義、遺伝子医学MOOK19号トランスポートソーム:生体膜輸送機構の全体像に迫る-基礎、臨床・創薬応用研究の最新成果

    • Author(s)
      金井好克
    • Publisher
      メディカル ドゥ(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Book] TRP Channels-Methods in Signal Transduction Series, Activation of TRP channels in mammalian systems

    • Author(s)
      Numata T, Kiyonaka S, Kato K, Takahashi N, Mori Y.
    • Publisher
      CRC press(in press)
    • Related Report
      2010 Annual Research Report
  • [Book] Handbook of Experimental Pharmacology : TRP channels in health and disease

    • Author(s)
      Numata T, Kiyonaka S, et al.
    • Publisher
      Physiology Review(In press)
    • Related Report
      2009 Annual Research Report
  • [Book] Bile Acid Biology and Therapeutic Actions

    • Author(s)
      Takada T, Suzuki H.
    • Publisher
      Springer(In press)
    • Related Report
      2009 Annual Research Report
  • [Book] Molecular mechanisms of membrane transport of vitamin E.

    • Author(s)
      Takada T, Suzuki H.
    • Publisher
      Mol Nutr Food Res(In press)
    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.osaka-u.ac.jp/pub/pharmal/transportsome/index.html

    • Related Report
      2010 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.med.osaka-u.ac.jp/pub/pharma1/transportsome/top.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.med.osaka-u.ac.jp/pub/pharmal/transportsome/top.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.osaka-u.ac.jp/pub/pharmal/transportsome/top.html

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.osaka-u.ac.jp/pub/pharma1/transportsome/top.html

    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 尿酸トランスポーター、並びに、尿酸輸送関連疾患素因及び炎症関連疾患素因の評価方法及び評価キット、検査体及び薬2009

    • Inventor(s)
      高田龍平, 鈴木洋史, 池淵祐樹, 伊藤晃成, 市田公美, 外
    • Industrial Property Number
      2009-148106
    • Acquisition Date
      2009-06-22
    • Related Report
      2009 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2018-08-07  

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