| Budget Amount *help |
¥148,400,000 (Direct Cost: ¥148,400,000)
Fiscal Year 2009: ¥25,200,000 (Direct Cost: ¥25,200,000)
Fiscal Year 2008: ¥26,100,000 (Direct Cost: ¥26,100,000)
Fiscal Year 2007: ¥26,300,000 (Direct Cost: ¥26,300,000)
Fiscal Year 2006: ¥44,700,000 (Direct Cost: ¥44,700,000)
Fiscal Year 2005: ¥26,100,000 (Direct Cost: ¥26,100,000)
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| Research Abstract |
We have utilized X-ray crystallography and electron microscopy to decipher the structural mechanism underlying recognition of extracellular environmental cues by cellular receptors. We have gained information about reelin signal transduction in brain development and Wnt signal transduction implicated in cancer and bone formation. Also, we have unraveled the structure of neuronal synapse adhesion machinery, and succeeded in visualizing the rice dwarf virus during the infection in situ.
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