| Budget Amount *help |
¥70,900,000 (Direct Cost: ¥70,900,000)
Fiscal Year 2009: ¥13,700,000 (Direct Cost: ¥13,700,000)
Fiscal Year 2008: ¥14,300,000 (Direct Cost: ¥14,300,000)
Fiscal Year 2007: ¥15,000,000 (Direct Cost: ¥15,000,000)
Fiscal Year 2006: ¥16,700,000 (Direct Cost: ¥16,700,000)
Fiscal Year 2005: ¥11,200,000 (Direct Cost: ¥11,200,000)
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| Research Abstract |
Reelin is essential for brain layer formation, but its exact function and underlying mechanism are nor well understood. We found that the C-terminal region of Reelin plays important roles in the interaction between this protein and neuronal cell membrane. We identified the protease in charge of specific proteolysis of Reelin. We also investigated when and where Reelin is received in the developing brain and found that Reelin acts on pre/early migratory neurons,
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