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Basement membrane regulation in C.elegans organogenesis

Research Project

Project/Area Number 17082011
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionKwansei Gakuin University (2008-2009)
The Institute of Physical and Chemical Research (2005-2007)

Principal Investigator

NISHIWAKI Kiyoji  Kwansei Gakuin University, 理工学部, 教授 (30342827)

Co-Investigator(Kenkyū-buntansha) KUBOTA Yukihiko  関西学院大学, 理工学部, 研究員 (70333325)
OHKURA Kiyotaka  独立行政法人理化学研究所, 細胞移動研究チーム, 研究員 (30415103)
IHARA Shinji  独立行政法人理化学研究所, 細胞移動研究チーム, 研究員 (70373272)
Project Period (FY) 2005 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥47,000,000 (Direct Cost: ¥47,000,000)
Fiscal Year 2009: ¥9,400,000 (Direct Cost: ¥9,400,000)
Fiscal Year 2008: ¥9,400,000 (Direct Cost: ¥9,400,000)
Fiscal Year 2007: ¥9,400,000 (Direct Cost: ¥9,400,000)
Fiscal Year 2006: ¥9,400,000 (Direct Cost: ¥9,400,000)
Fiscal Year 2005: ¥9,400,000 (Direct Cost: ¥9,400,000)
Keywords線虫 / ADAMTS family / MIG-17 / 抑圧遺伝子 / fibulin / nidogen / type IV collagen / ADAM family / 基底膜
Research Abstract

An ADAMTS family protease MIG-17 is recruited to the gonadal basement membrane in a prodomain-dependent manner, where it is activated to control gonadal leader cell migration in Caenorhabditis elegans. We found that fibulin-1 and type IV collagen act downstream of MIG-17 to recruit nidogen and that type IV collagen also activates a nidogen-independent pathway for directional control of leader cell migration.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (85 results)

All 2010 2009 2008 2007 2006 2005 Other

All Journal Article (29 results) (of which Peer Reviewed: 18 results) Presentation (52 results) Book (2 results) Remarks (2 results)

  • [Journal Article] mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV(C.elegans)2010

    • Author(s)
      Kawano, T.
    • Journal Title

      Development 136

      Pages: 1433-1442

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] C. elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV.2009

    • Author(s)
      Kawano, T., Zheng, H., Merz, D.C., Kohara, Y., Tamai, K.K., Nishiwaki, K., Culotti, J.G.
    • Journal Title

      Development 136

      Pages: 1433-1442

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] MIG-17/ADAMTS controls cell migration by recruiting nidogen to the basement membrane in C.2008

    • Author(s)
      Kubota, Y., Ohkura, K., Tamai, K.K., Nagata, K., Nishiwaki, K.
    • Journal Title

      elegans. Proc. Natl. Acad. Sci. USA 105

      Pages: 20804-20809

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stage-specific activation of MIG-17/ADAMTS controls cell migration in Caenorhabditis elegans2008

    • Author(s)
      Ihara, S., Nishiwaki, K.
    • Journal Title

      FEBS J. 275

      Pages: 4296-4305

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Stage-specific activation of MIG-17/ADAMTS controls cell migration in Caenorhabditis elegans2008

    • Author(s)
      Ihara, S
    • Journal Title

      EBFS J. 275

      Pages: 4296-4305

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MIG-17/ADAMTS controls cell migration by recruiting nidogen to the basement membrane in C. elegans2008

    • Author(s)
      Kubota, Y
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages: 20804-20809

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] bHLH transcription factors regulate organ morphogenesis via activation of an ADAMTS protease in C.2007

    • Author(s)
      Tamai, K.K., Nishiwaki, K.
    • Journal Title

      elegans. Dev. Biol. 308

      Pages: 562-571

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prodomain-dependent tissue targeting of an ADAMTS protease controls cell migration in Caenorhabditis elegans.2007

    • Author(s)
      Ihara, S., Nishiwaki, K.
    • Journal Title

      EMBO J. 26

      Pages: 2607-2620

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in C. elegans.2007

    • Author(s)
      Takasaki, T., Liu, Z., Habara, Y., Nishiwaki, K., Nakayama, J., Inoue, K., Sakamoto, H., Strome, S.
    • Journal Title

      Development 134

      Pages: 757-767

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] プロドメインがADAMTSプロテアーゼの組織局在に必須である2007

    • Author(s)
      伊原伸治、西脇清二
    • Journal Title

      実験医学 25

      Pages: 2891-2894

    • Related Report
      2009 Final Research Report
  • [Journal Article] 分泌型ADAMTSプロテアーゼによる器官形成の制御2007

    • Author(s)
      久保田幸彦、西脇清二
    • Journal Title

      細胞工学 26

      Pages: 1136-1141

    • Related Report
      2009 Final Research Report
  • [Journal Article] 特集「細胞外環境による形態形成の制御-新しい生物学の胎動」2007

    • Author(s)
      西脇清二
    • Journal Title

      細胞工学 26,10月号

      Pages: 1110-1112

    • NAID

      40015639106

    • Related Report
      2009 Final Research Report
  • [Journal Article] bHLH transcription factors regulate organ morphogenesis via activation of an ADAMTS protease in C. elegans.2007

    • Author(s)
      Tamai, K.K.
    • Journal Title

      Dev. Biol. 308

      Pages: 562-571

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prodomain-dependent tissue targeting of an ADAMTS protease controls cell migration in Caenorhabditis elegans.2007

    • Author(s)
      Ihara, S.
    • Journal Title

      EMBO J. 26

      Pages: 2607-2620

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in C. elegans.2007

    • Author(s)
      Takasaki, T.
    • Journal Title

      Development 134

      Pages: 757-767

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] プロドメインがADAMTSプロテアーゼの組織局在に必須である2007

    • Author(s)
      伊原伸治
    • Journal Title

      実験医学 25

      Pages: 2891-2894

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 分泌型ADAMTSプロテアーゼによる器官形成の制御2007

    • Author(s)
      久保田幸彦
    • Journal Title

      細胞工学 26

      Pages: 1136-1141

    • Related Report
      2007 Annual Research Report
  • [Journal Article] 細胞外環境による形態形成の制御-新しい生物学の胎動2007

    • Author(s)
      西脇清二
    • Journal Title

      細胞工学 26

      Pages: 1110-1112

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Chondroitin acts in the guidance of gonadal distal tip cells in C. elegans.2006

    • Author(s)
      Suzuki, N., Toyoda, H., Sano, M., Nishiwaki, K.
    • Journal Title

      Dev. Biol. 300

      Pages: 635-646

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Behavioral genetics of Caenorhabditis elegans unc-103-encoded erg-like K(+) channel.2006

    • Author(s)
      Reiner, D.J., Weinshenker, D., Tian, H., Thomas, J.H., Nishiwaki, K., Miwa, J., Gruninger, T., Leboeuf, B., Garcia, L.R.
    • Journal Title

      J. Neurogenet 20

      Pages: 41-66

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase.2006

    • Author(s)
      Rottiers, V., Motola, D.L., Gerisch, B., Cummins, C.L., Nishiwaki, K., Mangelsdorf, D.J., Antebi A.
    • Journal Title

      Dev. Cell 10

      Pages: 1-10

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans.2006

    • Author(s)
      Kubota, Y., Sano, M., Goda, S., Suzuki, N., Nishiwaki, K.
    • Journal Title

      Development 133

      Pages: 263-273

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] C. elegans as a model system to study the function of the COG complex in animal development.2006

    • Author(s)
      Kubota, Y., Nishiwaki, K.
    • Journal Title

      Biol. Chem. 387

      Pages: 1031-1035

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase.2006

    • Author(s)
      Rottiers, V.
    • Journal Title

      Dev. Cell 10

      Pages: 1-10

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Behavioral genetics of Caenorhabditis elegans unc-103-encoded erg-like K(+) channel.2006

    • Author(s)
      Reiner, D. J.
    • Journal Title

      J. Neurogenet. 20

      Pages: 41-66

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Chondroitin acts in the guidance of gonadal distal tip cells in C. elegans.2006

    • Author(s)
      Suzuki, N.
    • Journal Title

      Dev. Biol. 300

      Pages: 635-646

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C.elegans.2006

    • Author(s)
      Yukihiko Kubota
    • Journal Title

      Development 133

      Pages: 263-273

    • Related Report
      2005 Annual Research Report
  • [Journal Article] SRC-1, a non-receptor type of protein tyrosine kinase, controls the direction of cell and growth cone migration in C. elegans.2005

    • Author(s)
      Itoh, B., Hirose, T., Takata, N., Nishiwaki, K., Koga, M., Ohshima, Y., Okada, M.
    • Journal Title

      Development 132

      Pages: 5161-5172

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] SRC-1, a non-receptor type of protein tyrosine kinase, controls the direction of cell and growth cone migration in C.elegans.2005

    • Author(s)
      Bunsho Itoh
    • Journal Title

      Development 132

      Pages: 5161-5172

    • Related Report
      2005 Annual Research Report
  • [Presentation] Mutations Affecting Cessation of Gonadal Leader Cell Migration in C.elegans2010

    • Author(s)
      Kikuchi, T.
    • Organizer
      CDB Symposium 2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-03-23
    • Related Report
      2009 Annual Research Report
  • [Presentation] Genetic suppressors of defective gonadogenesis in gon-1 (ADAMTS Metalloprotease) mutants in C. elegans.2009

    • Author(s)
      Masaki Kakehi, Yukihiko Kubota, Kiyoji Nishiwaki
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Final Research Report
  • [Presentation] Fibulin-1 interacts with type IV collagen to regulate GON-1/ADAMTS activity and DBL-1/BMP signaling in C. elegans.2009

    • Author(s)
      Yukihiko Kubota, Kayo Nagata, Kiyoji Nishiwaki
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Final Research Report
  • [Presentation] C. elegansコンドロイチン重合因子MIG-22の優性変異による. MIG-17/ADAMTS欠損の抑圧に関与する分子の同定2009

    • Author(s)
      佐々壽浩、豊田英尚、大蔵清貴、西脇清二
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2009-12-09
    • Related Report
      2009 Final Research Report
  • [Presentation] C. elegansのMIG-17/ADAMTSはnidogenを基底膜にリクルートすることにって細胞移動を制御する2009

    • Author(s)
      久保田幸彦、大蔵清貴、玉井克幸、長田香代、西脇清二
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2009-12-09
    • Related Report
      2009 Final Research Report
  • [Presentation] Fibulin-1 interacts with type IV collagen to regulate GON-1/ADAMTS activity and DBL-1/BMP signaling in C.elegans2009

    • Author(s)
      Kubota, Y
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] The C.elegans spectraplakin VAB-10 regulates nuclear migration in the gonadal distal tip cells2009

    • Author(s)
      Kim, H
    • Organizer
      第32回日本分子物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] mig-18, a gene involved in gonad morphogenesis in C.elegans2009

    • Author(s)
      Mizutani, K.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Mutations affecting the cessation of gonadal leader cell migration in C.elegans2009

    • Author(s)
      Kikuchi, T.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analysis of tk97, a mutant defective in gonad morphogenesis in C.elegans2009

    • Author(s)
      Mori, M.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Genetic suppressors of defective gonadogenesis in gon-1(ADAMTS Metalloprotease) mutants in C.elegans2009

    • Author(s)
      Kakehi, M.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Analysis of DRAG-1, a novel axon guidance molecule in C.elegans2009

    • Author(s)
      Tsutsui, K.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fibulin-1 interacts with type IV collagen to regulate GON-1/ADAMTS activity and DBL-1/BMP signaling in C. elegans.2009

    • Author(s)
      Yukihiko Kubota, Kiyoji Nishiwaki
    • Organizer
      Gordon Research Conference on Matrixmetalloproteinases
    • Place of Presentation
      Les Diablerets, Switzerland
    • Year and Date
      2009-09-03
    • Related Report
      2009 Final Research Report
  • [Presentation] Fibulin-1 interacts with type IV collagen to regulate GON-1/ADAMTS activity and DBL-1/BMB signaling in C.elegans2009

    • Author(s)
      Kubota, Y.
    • Organizer
      Gordon Research Conference on Matrixmetalloproteinases
    • Place of Presentation
      Les Diablerets, Switzerland
    • Year and Date
      2009-09-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] mig-18 encodes a novel protein required for directed migration of distal tip cells2009

    • Author(s)
      Kitano, Y.
    • Organizer
      17^<th> International C.elegans Meeting
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      2009-06-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] The C.elegans spectraplakin mig-31 regulates nuclear migration in distal tip cells2009

    • Author(s)
      Kim.H
    • Organizer
      17^<th> International C.elegans Meeting
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      2009-06-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] C. elegansコンドロイチン重合因子MIG-22の優性変異によるMIG-17/ADAMTS欠損の抑圧に関与する分子の同定2008

    • Author(s)
      佐々壽浩
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] The C. elegans spectraplakin mig-31 plays a novel role in regulation of distal tip cell migration2008

    • Author(s)
      金憲誠
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] C. elegansのMIG-17/ADAMTSはnidogenを基底膜にリクルートすることによって細胞移動を制御する2008

    • Author(s)
      久保田幸彦
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] C. elegansのMIG-34は細胞移動を制御する2008

    • Author(s)
      仲矢圭吾
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] 線虫C. elegansの細胞移動変異体mig-18の解析2008

    • Author(s)
      北野優子
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] 線虫C. elegansの生殖巣形態形成を制御するmig-35遺伝子の解析2008

    • Author(s)
      水谷賀江
    • Organizer
      BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] MIG-17/ADAMTS controls cell migration by recruiting nidogen to the basement membrane in C. elegans.2008

    • Author(s)
      Kubota, Y., Ohkura, K., Nagata, K., Tamai, K.K., Nishiwaki, K.
    • Organizer
      American Society for Matrix Biology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-12-07
    • Related Report
      2009 Final Research Report
  • [Presentation] MIG-17/ADAMTS controls cell migration by recruiting nidogen to the basement membrane in C. elegans2008

    • Author(s)
      Kubota, Y
    • Organizer
      American Society for Matrix Biology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-12-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] Suppression of mig-17 DTC migration defects by a dominant mutation in mig-22.2008

    • Author(s)
      Toshihiro Sassa, Hidenao Toyoda, Kiyotaka Ohkura, Kiyoji Nishiwaki.
    • Organizer
      East Asia C. elegans Meeting
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2008-04-18
    • Related Report
      2009 Final Research Report
  • [Presentation] 発生段階に依存したC. elegans ADAMTSプロテアーゼMIG活性化2007

    • Author(s)
      伊原伸治西脇清二
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Related Report
      2009 Final Research Report
  • [Presentation] Molecular cascade downstream of MIG-17/ADAMTS controlling organ morphogenesis in C. elegans.2007

    • Author(s)
      Yukihiko Kubota, Kiyotaka Ohkura, Kayo Nagata, Kiyoji Nishiwaki
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-11
    • Related Report
      2009 Final Research Report
  • [Presentation] A dominant mutation of mig-22 suppresses DTC migration defects of mig-17.2007

    • Author(s)
      Sassa, T., Nishiwaki, K.
    • Organizer
      16th International C. elegans Meeting
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2007-06-27
    • Related Report
      2009 Final Research Report
  • [Presentation] Molecular cascade downstream of MIG-17/ADAMTS controlling cell migration in C. elegans.2007

    • Author(s)
      Kubota, Y., Ohkura, K., Nagata, K., Nishiwaki K.
    • Organizer
      16th International C. elegans Meeting
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2007-06-27
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] Molecular cascade downstream of MIG-17/ADAMTS controlling cell migration in C. elegans.2007

    • Author(s)
      Nishiwaki, K.
    • Organizer
      Gordon Research Conference on Matrix Metalloproteinases
    • Place of Presentation
      Il Ciocco, Italy
    • Year and Date
      2007-06-03
    • Related Report
      2009 Final Research Report
  • [Presentation] Prodomain-dependent tissue targeting and activation of MIG-17, an ADAMTS protease controlling cell migration in Caenorhabditis elegans.2007

    • Author(s)
      Ihara, S., Nishiwaki, K.
    • Organizer
      Gordon Research Conference on Matrix Metalloproteinases
    • Place of Presentation
      Il Ciocco, Italy
    • Year and Date
      2007-06-03
    • Related Report
      2009 Final Research Report
  • [Presentation] C. elegansのADAMTSプロテアーゼMIG-17による器官形成の制御2007

    • Author(s)
      西脇清二
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会 合同大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] C. elegansのADAMTSプロテアーゼMIG-17による器官形成の制御2007

    • Author(s)
      久保田幸彦、大蔵清貴、長田香代、西脇清二
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡
    • Year and Date
      2007-05-27
    • Related Report
      2009 Final Research Report
  • [Presentation] C. elegansの器官形成における細胞移動を制御するMIG-17/ADAMTSの下流カスケード2007

    • Author(s)
      久保田幸彦
    • Organizer
      第54回マトリックス研究会大会
    • Place of Presentation
      東京
    • Year and Date
      2007-05-09
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular cascade downstream of MIG-17/ADAMTS controling cell migration in C. elegans2007

    • Author(s)
      Nishiwaki, K.
    • Organizer
      Gordon Research Conference on Matrix Metalloproteinases
    • Place of Presentation
      I1 Ciocco, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] Prodomain-dependent tissue targeting and activation of MIG-17, an ADAMTS protease controlling cell migration in Caenorhabditis elegans.2007

    • Author(s)
      Ihara, S.
    • Organizer
      Gordon Research Conference on Matrix Metalloproteinases
    • Place of Presentation
      I1 Ciocco, Italy
    • Related Report
      2007 Annual Research Report
  • [Presentation] A dominant mutation of mig-22 suppresses DTC migration defects of mig-172007

    • Author(s)
      Sassa, T.
    • Organizer
      16th International C. elegans Meeting
    • Place of Presentation
      Los Angels, USA
    • Related Report
      2007 Annual Research Report
  • [Presentation] Molecular cascade downstream of MIG-17/ADAMTS controlling cell migration in C. elegans.2007

    • Author(s)
      久保田幸彦
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] 発生段階に依存したC. elegans ADAMTSプロテアーゼMIG-17の活性化2007

    • Author(s)
      伊原伸治
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] mig-22遺伝子の優性変異はmig-17変異体のDTC移動異常を抑圧する2007

    • Author(s)
      佐々壽浩
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] C. elegansのmig-31遺伝子はスペクトラプラキンをコードする2007

    • Author(s)
      金 憲誠
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      横浜
    • Related Report
      2007 Annual Research Report
  • [Presentation] C. elegansの器官形成における基底膜ADAMTSプロテアーゼMIG-17の役割2006

    • Author(s)
      西脇清二
    • Organizer
      分子生物学会2006 forum
    • Place of Presentation
      名古屋
    • Year and Date
      2006-12-06
    • Related Report
      2009 Final Research Report
  • [Presentation] Molecular dissection of MIG-17, an ADAMTS family protease that controls cell migration in C. elegans.2006

    • Author(s)
      Shinji Ihara, Kiyoji Nishiwaki
    • Organizer
      East Asia C. elegans Meeting
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2006-11-15
    • Related Report
      2009 Final Research Report
  • [Presentation] fibulin-1 dominant mutations suppress cell migration defects of mig-17 mutants in a nidogen-1-dependent manner in C. elegans.2006

    • Author(s)
      Yukihiko Kubota, Kayo Nagata, Kiyoji Nishiwaki
    • Organizer
      East Asia C. elegans Meeting
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2006-11-15
    • Related Report
      2009 Final Research Report
  • [Presentation] C. elegans fibulin-1の優性変異はnidogen-1に依存してmig-17変異体の細胞移動異常を抑圧する2005

    • Author(s)
      久保田幸彦, 黒木理恵, 西脇清二
    • Organizer
      第28回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2005-12-07
    • Related Report
      2009 Final Research Report
  • [Presentation] Role of MIG-17 ADAM protease that controls organ morphogenesis in C. elegans.2005

    • Author(s)
      Nishiwaki, K.
    • Organizer
      第78回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2005-10-19
    • Related Report
      2009 Final Research Report
  • [Presentation] THE COG COMPLEX ACTS IN ORGAN MORPHOGENESIS VIA GLYCOSYLATION OF AN ADAM PROTEASE IN C. ELEGANS.2005

    • Author(s)
      Nishiwaki, K.
    • Organizer
      4th General Meeting of International Proteolysis Society
    • Place of Presentation
      Quebec City, Canada
    • Year and Date
      2005-10-15
    • Related Report
      2009 Final Research Report
  • [Presentation] ADAMs in migration of distal tip cells in C. elegans.2005

    • Author(s)
      Nishiwaki, K.
    • Organizer
      The Gordon Research Conference on Matrix Metalloproteinases
    • Place of Presentation
      Montana, USA
    • Year and Date
      2005-08-28
    • Related Report
      2009 Final Research Report
  • [Presentation] FBL-1 interacts with ADAM proteases and NID-1 to control cell migration in C. elegans.2005

    • Author(s)
      Yukihiko Kubota, Rie Kuroki, Kiyoji Nishiwaki.
    • Organizer
      15th International C. elegans Meeting
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2005-06-26
    • Related Report
      2009 Final Research Report
  • [Presentation] Specific mutations in type IV collagen suppress the cell migration defects in mig-17 mutants.2005

    • Author(s)
      Kiyotaka Ohkura, Kiyoji Nishiwaki
    • Organizer
      15th International C. elegans Meeting
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2005-06-26
    • Related Report
      2009 Final Research Report
  • [Presentation] Glycosylation of MIG-17 ADAM proteaseessential for controlling cell migration in C. elegans.2005

    • Author(s)
      Ihara, S., Nishiwaki, K.
    • Organizer
      15th International C. elegans Meeting
    • Place of Presentation
      Los Angels, USA
    • Year and Date
      2005-06-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 線虫C. elegansの器官形成における分泌型ADAMプロテアーゼMIG-17の役割2005

    • Author(s)
      西脇清二
    • Organizer
      第37回日本結合組織学会学術大会
    • Place of Presentation
      富山
    • Year and Date
      2005-05-26
    • Related Report
      2009 Final Research Report
  • [Book] Principles of Developmental Genetics(Sally A. Moody, ed. )2007

    • Author(s)
      Nishiwaki, K., Kubota, Y
    • Publisher
      Academic Press
    • Related Report
      2009 Final Research Report
  • [Book] Principles of DEVELOPMENTAL GENETYCS2007

    • Author(s)
      Sally A. Moody (Editor)
    • Total Pages
      1104
    • Publisher
      ACADEMIC PRESS
    • Related Report
      2007 Annual Research Report
  • [Remarks]

    • URL

      http://sci-tech.ksc.kwansei.ac.jp/~nishiwaki/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://sci-tech.ksc.kwansei.ac.jp/~nishiwaki/

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2018-03-28  

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