Elucidation of the process by which social skills develop using noninvasive functional neuroimaging to quantitate multiple individual interactions and analysze their interaction

• Project/Area Number: 17100003
• Research Category: Grant-in-Aid for Scientific Research (S)
• Allocation Type: Single-year Grants
• Research Field: Cognitive science
• Research Institution: National Institute for Physiological Sciences
• Principal Investigator: SADATO Norihiro National Institute for Physiological Sciences, 大脳皮質機能研究系, 教授 (00273003)
• Co-Investigator(Kenkyū-buntansha): MAYUMI Mitsuhumi 福井大学, 医学部, 教授 (70135581) ; NAKAI Akio 福井大学, 医学部, 助教 (50240784) ; MATSUKI Ken-ichi 福井大学, 教育地域科学部, 教授 (10157282) ; KOEDA Tatsuya 鳥取大学, 地域学部, 教授 (70225390) ; OHNO Kousaku 鳥取大学, 医学部, 教授 (70112109) ; ITAKURA Shoji 京都大学, 文学部, 准教授 (50211735) ; OZAKI Toru 統計数理研究所, 予測制御研究系, 教授 (00000208) ; YONEKURA Yoshiharu 福井大学, 高エネルギー医学研究センター, 教授 (60135572)
• Project Period (FY): 2005 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥105,040,000 (Direct Cost: ¥80,800,000、Indirect Cost: ¥24,240,000); Fiscal Year 2009: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000); Fiscal Year 2008: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000); Fiscal Year 2007: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000); Fiscal Year 2006: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000); Fiscal Year 2005: ¥69,680,000 (Direct Cost: ¥53,600,000、Indirect Cost: ¥16,080,000)
• Keywords: 心の理論 / 対面コミュニケーション / 機能的MRI / 共同注意 / 視線計測 / 脳血流 / 学習 / 言語

Research Abstract

社会能力の正常な獲得過程において順序だてて出現する行動里標に注目し、それらの神経基盤を抽出した。社会的信号に対する選好性である生物感は初期視覚処理を担う領域で表象される事、共感や語用論において心の理論が重要である事、恐れ刺激に対する扁桃体での自動的な神経反応が文化的な同調を受ける事を示した。さらにヒトの向社会行動の誘因の一つである社会報酬が金銭報酬獲得時と同様に報酬系を賦活する事を明らかにした。

Research Products

• [Journal Article] Listening to rhythms activates motor and premotor cortices. (2009)
  • Author(s): Bengtsson SL, Ullen F, Ehrsson HH, Hashimoto T, Kito T, Naito E, Forssberg H, Sadato N
  • Journal Title: Cortex 45 Pages: 62-71
  • Peer Reviewed
• [Journal Article] Dynamic Cultural Influences on Neural Representations of the Self. (2009)
  • Author(s): Chiao JY, Harada T, Komeda H, Li Z, Mano Y, Saito D, Parrish TB, Sadato N, Iidaka T
  • Journal Title: J Cogn Neurosci (in press)
  • Peer Reviewed
• [Journal Article] Visuokinesthetic perception of hand movement is mediated by cerebro-cerebellar interaction between the left cerebellum and right parietal cortex. (2009)
  • Author(s): Hagura N, Oouchida Y, Aramaki Y, Okada T, Matsumura M, Sadato N, Naito E
  • Journal Title: Cereb Cortex 19 Pages: 176-186
  • Peer Reviewed
• [Journal Article] Neural correlates of the judgment of lying: A functional magnetic resonance imaging study. (2009)
  • Author(s): Harada T, Itakura S, Xu F, Lee K, Nakashita S, Saito DN, Sadato N
  • Journal Title: Neurosci Res 63 Pages: 24-34
  • NAID: 10027499140
  • Peer Reviewed
• [Journal Article] Processing of the Incentive for Social Approval in the Ventral Striatum during Charitable Donation. (2009)
  • Author(s): Izuma K, Saito DN, Sadato N
  • Journal Title: J Cogn Neurosci (in press)
  • Peer Reviewed
• [Journal Article] Perspective-taking as part of narrative comprehension: a functional MRI study. (2009)
  • Author(s): Mano Y, Harada T, Sugiura M, Saito DN, Sadato N
  • Journal Title: Neuropsychologia 47 Pages: 813-824
  • Peer Reviewed
• [Journal Article] Ventrolateral prefrontal cortex activity associated with individual differences in arbitrary delayed paired-association learning performance: A functional magnetic resonance imaging study. (2009)
  • Author(s): Tanabe HC, Sadato N
  • Journal Title: Neuroscience 160 Pages: 688-697
  • Peer Reviewed
• [Journal Article] Neural codes for somatosensory two-point discrimination in inferior parietal lobule: an fMRI study. (2008)
  • Author(s): Akatsuka K, Noguchi Y, Harada T, Sadato N, Kakigi R
  • Journal Title: Neuroimage 40 Pages: 852-858
  • Peer Reviewed
• [Journal Article] Cultural specificity in amygdala response to fear faces. (2008)
  • Author(s): Chiao JY, Iidaka T, Gordon HL, Nogawa J, Bar M, Aminoff E, Sadato N, Ambady N
  • Journal Title: J Cogn Neurosci 20 Pages: 2167-2174
  • Peer Reviewed
• [Journal Article] Neural basis of individualistic and collectivistic views of self. (2008)
  • Author(s): Chiao JY, Harada T, Komeda H, Li Z, Mano Y, Saito D, Parrish TB, Sadato N, Iidaka T
  • Journal Title: Hum Brain Mapp (in press)
  • Peer Reviewed
• [Journal Article] Hemispheric asymmetry of frequency-dependent suppression in the ipsilateral primary motor cortex during finger movement: a functional magnetic resonance imaging study. (2008)
  • Author(s): Hayashi MJ, Saito DN, Aramaki Y, Asai T, Fujibayashi Y, Sadato N
  • Journal Title: Cereb Cortex 18 Pages: 2932-2940
  • Peer Reviewed
• [Journal Article] Processing of social and monetary rewards in the human striatum. (2008)
  • Author(s): Izuma K, Saito DN, Sadato N
  • Journal Title: Neuron 58 Pages: 284-294
  • Peer Reviewed
• [Journal Article] Asymmetric control mechanisms of bimanual coordination: an application of directed connectivity analysis to kinematic and functional MRI data. (2008)
  • Author(s): Maki Y, Wong KF, Sugiura M, Ozaki T, Sadato N
  • Journal Title: Neuroimage 42 Pages: 1295-1304
  • Peer Reviewed
• [Journal Article] Visual image reconstruction from human brain activity using a combination of multiscale local image decoders. (2008)
  • Author(s): Miyawaki Y, Uchida H, Yamashita O, Sato MA, Morito Y, Tanabe HC, Sadato N, Kamitani Y
  • Journal Title: Neuron 60 Pages: 915-929
  • Peer Reviewed
• [Journal Article] The neural basis of academic achievement motivation. (2008)
  • Author(s): Mizuno K, Tanaka M, Ishii A, Tanabe HC, Onoe H, Sadato N, Watanabe Y
  • Journal Title: Neuroimage 42 Pages: 369-378
  • Peer Reviewed
• [Journal Article] The role of the right prefrontal cortex in self-evaluation of the face: a functional magnetic resonance imaging study. (2008)
  • Author(s): Morita T, Itakura S, Saito DN, Nakashita S, Harada T, Kochiyama T, Sadato N
  • Journal Title: J Cogn Neurosci 20 Pages: 342-355
  • NAID: 130007039521
  • Peer Reviewed
• [Journal Article] Cross-modal integration during vowel identification in audiovisual speech: a functional magnetic resonance imaging study. (2008)
  • Author(s): Murase M, Saito DN, Kochiyama T, Tanabe HC, Tanaka S, Harada T, Aramaki Y, Honda M, Sadato N
  • Journal Title: Neurosci Lett 434 Pages: 71-76
  • Peer Reviewed
• [Journal Article] Tactile-visual integration in the posterior parietal cortex: a functional magnetic resonance imaging study. (2008)
  • Author(s): Nakashita S, Saito DN, Kochiyama T, Honda M, Tanabe HC, Sadato N
  • Journal Title: Brain Res Bull 75 Pages: 513-525
  • Peer Reviewed
• [Journal Article] Source of nonlinearity of the BOLD response revealed by simultaneous fMRI and NIRS. (2008)
  • Author(s): Toyoda H, Kashikura K, Okada T, Nakashita S, Honda M, Yonekura Y, Kawaguchi H, Maki A, Sadato N
  • Journal Title: Neuroimage 39 Pages: 997-1013
  • Peer Reviewed
• [Journal Article] Functional segregation of the inferior frontal gyrus for syntactic processes: a functional magnetic-resonance imaging study. (2008)
  • Author(s): Uchiyama Y, Toyoda H, Honda M, Yoshida H, Kochiyama T, Ebe K, Sadato N
  • Journal Title: Neurosci Res 61 Pages: 309-318
  • Peer Reviewed
• [Journal Article] Processing of social and monetary rewards in the human striatum (2008)
  • Author(s): Izuma K, Saito DN, Sadato N
  • Journal Title: Neuron 58 Pages: 284-294
  • Peer Reviewed
• [Journal Article] The role of the right prefrontal cortex in self-evaluation of the face : a functional magnetic resonance imaging study (2008)
  • Author(s): Morita T, Itakura S, Saito DN, Nakashita S, Harada T, Kochiyama T, Sadato N
  • Journal Title: Journal of Cognitive Neuroscience 20 Pages: 342-355
  • NAID: 130007039521
  • Peer Reviewed
• [Journal Article] The neural basis of academic achievement motivation (2008)
  • Author(s): Mizuno K, Tanaka M, Ishii A, Tanabe HC, Onoe H, Sadato N, Watanabe Y
  • Journal Title: Neuroimage 42 Pages: 369-378
  • Peer Reviewed
• [Journal Article] Source of nonlinearity of the BOLD response revealed by simultaneous fMRI and NIRS (2008)
  • Author(s): Toyoda H, Kashikura K, Okada T, Nakashita S, Honda M, Yonekura Y, Kawaguchi H, Maki A, Sadato N
  • Journal Title: Neuroimage 39 Pages: 997-1013
  • Peer Reviewed
• [Journal Article] The Role of the Right Prefrontal Cortex in Self-Evaluation of the Face:A Functional Magnetic Resonance Imaging Study (2008)
  • Author(s): Morita T, Itaktua S, Saito DN, Nakashita S, Harada T, Kochiyama T, Sadato N
  • Journal Title: Journal of Cognitive Neuroscience 20 Pages: 1-4
  • Peer Reviewed
• [Journal Article] Neural substrates of intermanual transfer of a newly acquired motor skill (2007)
  • Author(s): Perez MA, Tanaka S, Wise SP, Sadato N, Tanabe HC, Willingham DT, Cohen LG
  • Journal Title: Current Biology 17 Pages: 1896-1902
  • Peer Reviewed
• [Journal Article] Suppression of the non-dominant motor cortex during bimanual symmetric finger movement : a functional magnetic resonance imaging study (2006)
  • Author(s): Aramaki Y, Honda M, Sadato N
  • Journal Title: Neuroscience 141 Pages: 2147-2153
• [Journal Article] Frontoparietal network involved in successful retrieval from episodic memory. Spatial and temporal analysis using fMRI and ERP. (2006)
  • Author(s): Iidaka T, Matsumoto A, Nogawa J, Yamamoto Y, Sadato N
  • Journal Title: Cereb Cortex 16 Pages: 1349-1360
• [Journal Article] Hemodynamic and electrophysiological relationship involved in human face processing : evidence from a combined fMRI-ERP study. (2006)
  • Author(s): Iidaka T, Matsumoto A, Haneda K, Okada T, Sadato N
  • Journal Title: Brain Cogn 60 Pages: 176-186
• [Journal Article] Multisensory activation of the intraparietal area when classifying grating orientation : a functional magnetic resonance imaging study. (2006)
  • Author(s): Kitada R, Kito T, Saito DN, Kochiyama T, Matsumura M, Sadato N, Lederman SJ
  • Journal Title: J Neurosci 26 Pages: 7491-7501
• [Journal Article] Practice makes perfect : the neural substrates of tactile discrimination by Mah-Jong experts include the primary visual cortex. (2006)
  • Author(s): Saito DN, Okada T, Honda M, Yonekura Y, Sadato N
  • Journal Title: BMC Neurosci 7 Pages: 79-79
• [Journal Article] Neural substrates of sarcasm : a functional magnetic-resonance imaging study. (2006)
  • Author(s): Uchiyama H, Seki A, Kageyama H, Saito DN, Koeda T, Ohno K, Sadato N
  • Journal Title: Brain Res 1124 Pages: 100-110
• [Journal Article] Functionally segregated neural substrates for arbitrary audiovisual paired-association learning (2005)
  • Author(s): Tanabe HC, Honda M, Sadato N
  • Journal Title: The Journal of Neuroscience 25 Pages: 6409-6418
• [Journal Article] How the blind "see" Braille : lessons from functional magnetic resonance imaging (2005)
  • Author(s): Sadato N
  • Journal Title: Neuroscientist 11 Pages: 577-582
• [Journal Article] Neural Correlates of the Spontaneous Phase Transition during Bimanual Coordination
  • Author(s): Aramaki Y, Honda M, Okada T, Sadato N
  • Journal Title: Cerebral Cortex (In press)
• [Journal Article] The Representation of the Human Oral Area in the Somatosensory Cortex : a Functional MRI Study
  • Author(s): Miyamoto JJ, Honda M, Saito DN, Okada, T, Ono T, Ohyama K, Sadato N
  • Journal Title: Cerebral Cortex (In press)
• [Presentation] The Neural Basis of Social Reward and Decision-Making. (2009)
  • Author(s): Sadato N
  • Organizer: ESF-JSPS Frontier Science Conference Series for Young Researchers Social Cognitive Neuroscience
  • Place of Presentation: Maratea, Italy
  • Year and Date: 2009-03-02
• [Remarks]
  • URL: http://www.nips.ac.jp/fmritms/