Skeletal muscle lipid content and their relation to body fat, physical fitness, exercise and lipid metabolizm by ^1H-MRS

• Project/Area Number: 17200040
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied health science
• Research Institution: Otaru University of Commerce
• Principal Investigator: NAKAGAWA Yoshinao Otaru University of Commerce, 商学部, 教授 (80201664)
• Co-Investigator(Kenkyū-buntansha): HATTORI Masaaki 北海道東海大学, 国際文化部, 教授 (70208544) ; OKANO Goro 札幌医科大学, 医学部, 准教授 (50117610) ; HARADA Kuniaki 札幌医科大学, 附属病院, 技師 (50423760)
• Project Period (FY): 2005 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥26,260,000 (Direct Cost: ¥20,200,000、Indirect Cost: ¥6,060,000); Fiscal Year 2008: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2007: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2006: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2005: ¥13,000,000 (Direct Cost: ¥10,000,000、Indirect Cost: ¥3,000,000)
• Keywords: 筋細胞内脂肪 / 加齢 / 体力 / 持久力 / スポーツ / プロトンMRS / クレアチン / 競技特性 / 最大酸素摂取量 / スキー / 体組成 / 水分量 / 筋細胞外脂肪 / エアロビクス / 筋断面積 / 筋水分量 / 加圧トレーニング / 骨格筋 / 脂質代謝 / クレアチニン / タンパク質 / 最大筋力

Research Abstract

筋細胞内脂肪はエアロビクスやクロスカントリースキーのような長時間種目のスポーツ競技をしている選手では脂肪を運動のエネルギーとして有利に活用するため骨格筋細胞内に脂肪を豊富に蓄積している。しかし、短時間の競技の選手では筋細胞内の脂肪量は少ない。本研究により筋細胞内脂肪量は加齢、食事、運動習慣による影響を受けていることが解明され、健康保持やスポーツにおいて適量を維持する必要性が示唆された。

Research Products

• [Journal Article] Intramyocellular lipids in elite femalecross-country skiers and biathletes (2008)
  • Author(s): Y. Nakagawa, M. Hattori, K. Harada, R.Shirase, J. SuzukiI, M. Bando, G. Okano
  • Journal Title: International Symposium on WinterSports Sciences Commemorating the 2008 Nordic Ski WC proceedings Pages: 66-70
• [Journal Article] Intramyocellular lipids in elite female cross-country skiers and biathletes (2008)
  • Author(s): Yoshinao Nakagawa
  • Journal Title: International Symposium on Winter Sports Sci Commemorating the 2007 NordicSki WC in Sapporo Pages: 66-70
• [Journal Article] Age-Related Changes in IntramyocellularLipid in Humans by in vivo ^1H-MRSpectroscopy (2007)
  • Author(s): Y. Nakagawa, M. Hattori, K. Harada, R.Shirase, M. Bando, G. Okano
  • Journal Title: Gerontology 53 Pages: 218-223
• [Journal Article] Age-Related Changes in Intramyocellular Lipid in Humans by in vivo ^1H-MR Spectroscopy. (2007)
  • Author(s): Yoshinao Nakagawa
  • Journal Title: Gerontology 53 Pages: 218-223
  • Peer Reviewed
• [Journal Article] Intramuscular lipid content in femaleendurance-trained elderly by in vivo ^1H-MR spectroscopy (2006)
  • Author(s): Y. Y.Nakagawa, M.Hattori, K. Harada, R. Shirase, M. Bando,G. Okano
  • Journal Title: Jpn J Phys Fitness Sports Med 55,(Suppl)
• [Journal Article] Characteristics of intramyocellularlipid content in skeletal muscles ofoverweight men and endurance-trainedathletes (2006)
  • Author(s): M. Hattori, Y. Nakagawa, K. Harada, M.Bando, G. Okano
  • Journal Title: Jpn J Phys Fitness Sports Med 55,(Suppl)
• [Journal Article] Intramuscular lipid content in female endurance-trained elderly by in vivo ^1H-MR spectroscopy (2006)
  • Author(s): Yoshinao.Nakagawa
  • Journal Title: Jpn J Phys Fitness Sports Med 55,(Suppl)
• [Journal Article] Characteristics of intramyocellular lipid content in skeletal muscles of overweight men and endurance-trained athletes (2006)
  • Author(s): Masaaki.Hattori
  • Journal Title: Jpn J Phys Fitness Sports Med 55,(Suppl)
  • NAID: 110004821442
• [Journal Article] ATP economy of force maintenance in human tibialis anterior muscle. (2005)
  • Author(s): Yoshinao Nakagawa
  • Journal Title: Medicine & Science in Sports & Exercise June(印刷中)
• [Presentation] 筋細胞内脂肪量における持久系とパワー系のスキー競技特性 (2008)
  • Author(s): 中川喜直
  • Organizer: 日本体力医学会
  • Place of Presentation: 別府ビーコンプラザ
  • Year and Date: 2008-09-18
• [Presentation] 筋細胞内脂肪量における持久系とパワー系のスキー競技特性 (2008)
  • Author(s): 中川喜直, 服部正明・相原博之, 岡野五郎
  • Organizer: 日本体力医学会
  • Place of Presentation: 別府
• [Presentation] ^1H-MRS法による骨格筋の細胞内・外脂肪量へ与える加圧歩行の影響 (2007)
  • Author(s): 中川喜直
  • Organizer: 日本体力医学会
  • Place of Presentation: 秋田 ノースアジア大学
  • Year and Date: 2007-09-15
• [Presentation] ^1H-MRS 法による骨格筋の細胞内・外脂肪量へ与える加圧歩行の影響 (2007)
  • Author(s): 中川喜直, 服部正明, 鎌倉一, 岡野五郎
  • Organizer: 日本体力医学会
  • Place of Presentation: 岡山
• [Presentation] Intramuscular lipid content in femaleendurance-trained elderly by in vivo ^1H-MR spectroscopy (2005)
  • Author(s): Y. Nakagawa, M.Hattori, K. Harada, R. Shirase, M.Bando, G. Okano
  • Organizer: Asian Federation ofSports Medicine Congress
  • Place of Presentation: Tokyo
• [Presentation] Characteristics of intramyocellularlipid content in skeletal muscles of overweight men and endurance-trained athletes (2005)
  • Author(s): M. Hattori, Y. Nakagawa, K.Harada, M. Bando, G. Okano
  • Organizer: Asian Federation of Sports MedicineCongress
• [Presentation] ^1H-MRS 法による高齢男性ランナーの骨格筋における細胞内・外の脂肪量 (2005)
  • Author(s): 中川喜直, 服部正明, 原田邦明、白勢竜二、大元秀近、板東道夫、岡野五郎
  • Organizer: 日本体力医学会【日本体力医学会マスカット賞受賞】
  • Place of Presentation: 岡山
• [Presentation] Intramyocellular lipids in elite femalecross-country skiers and biathletes
  • Author(s): Y. Nakagawa, M. HattoriI, K. Harada R.Shirase, J. SuzukiI, M. Bando, G. Okano
  • Organizer: International Symposium on Winter Sports Sciences Commemoratingthe 2007 Nordic Ski WC in Sapporo