| Project/Area Number |
17207019
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
生理人類学
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| Research Institution | Kanazawa University |
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Principal Investigator |
FUJIWARA Katsuo Kanazawa University, Graduate School of Medical Science, Professor (60190089)
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| Co-Investigator(Kenkyū-buntansha) |
MORI Akio Nihon Univerdty, College of Humanities and Sciences, Professor (30060148)
MURAKAMI Shinji Sapporo Medical University, School of flealth Sdenco, Professor (30142756)
KUNITA Kenji Osaka City University, Research Center for Urban Health and Sports, Associate Professor (20316003)
TOYAMA Hiroshi Kanazawa University, Graduate School of Medical Sdence, Associate Professor (10172206)
WATANABE Hitoshi Osaka City University, Research Center for Urban Health and Sports, Professor (50167160)
小澤 治夫 東海大学, 体育学部, 教授 (60360963)
室 増男 東邦大学, 医学部, 教授 (80112887)
福岡 義之 熊本県立大学, 環境共生学部, 教授 (20265028)
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| Project Period (FY) |
2005 – 2007
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| Project Status |
Completed (Fiscal Year 2007)
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| Budget Amount *help |
¥49,400,000 (Direct Cost: ¥38,000,000、Indirect Cost: ¥11,400,000)
Fiscal Year 2007: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Fiscal Year 2006: ¥10,400,000 (Direct Cost: ¥8,000,000、Indirect Cost: ¥2,400,000)
Fiscal Year 2005: ¥30,680,000 (Direct Cost: ¥23,600,000、Indirect Cost: ¥7,080,000)
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| Keywords | Neck flexion position / Periodic movement / Brain activation / Attention / Voluntary movement / Reaction time of eve movement / Prefrontal cortex / Cerebral blood flow / 大脳皮質局所血流量 / 脳周波数分析 / 頚部前屈 / 感覚刺激誘発電位 / 磁気刺激運動誘発電位 / 脳波周波数分析 / 筋血流量 |
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| Research Abstract |
Firstly, we investigated the brain activation caused by neck flexion and observed following findings: Facilitation of various sensory brain evoked potentials and increment of cerebral blood flows in the relevant brain regions; Increments of amplitude in contingent negative variation and preceding action time of postural muscles during bilateral arm movement; Shortening of P300 latency and increase of P300 amplitude at Pz site during the arm movement; Decrease in negative peak amplitude at Cz cite associated with the anti-saccade; Increase in motor evoked potentials recorded from the upper limb muscles, elector spinae and rectus femoris by transcranial magnetic stimulation to the motor cortex. Furthermore, vibration stimulation effects to the trapezius were found for shortening of reaction times in visually-guided, memory-guided and anti saccades. The shortening of reaction times in the latter two saccades was noticeable.
Next, we investigated the brain activation during saccade caused b
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y periodic movements (respiration, mastication, gait, floor oscillation, and repetitive neck flexion). Duration of the movement tasks was 2 or 3 minutes. The former 3 movements were performed in two ways: one was more automatic and another was more voluntary Floor oscillation was adopted as an automatic periodic movement, while repetitive neck flexion as a voluntary movement. Apparent brain activation was observed only for one minute after voluntary periodic movement. Particularly, high brain activation was found during antisaccade after repetitive neck flexion.
Finally, we investigated training effects of brain activation caused by neck flexion and periodic movement, subjected healthy elderly adults and dementia patients. Antisaccade task or touch panel task was adopted as training for 3 weeks or one month. In the elderly, significant training effects were found in antisaccade task, especially with neck flexion, and in touch panel training. In the patients with frontal lobe atrophy, effects by touch panel training were found in antisaccade task. Less
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