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The effect of fragile fracture and bone marker to activity of daily living and death

Research Project

Project/Area Number 17207021
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field 生理人類学
Research InstitutionNagasaki University

Principal Investigator

AOYAGI Kiyoshi  Nagasaki University, 大学院・医歯薬学総合研究科, 教授 (80295071)

Co-Investigator(Kenkyū-buntansha) ABE Yasuyo  長崎大学, 大学院・医歯薬学総合研究科, 助教 (90372771)
TAKAMURA Noboru  長崎大学, 大学院・医歯薬学総合研究科, 教授 (30295068)
SHIBDO Hiroyuki  長崎大学, 大学院・医歯薬学総合研究科, 教授 (30107677)
OSAKI Makoto  長崎大学, 大学院・医歯薬学総合研究科, 講師 (20380959)
MEDA Takahiro  長崎大学, 大学院・医歯薬学総合研究科 (40284674)
中里 未央  長崎大学, 大学院・医歯薬学総合研究科, 助教 (00380973)
Co-Investigator(Renkei-kenkyūsha) YE ZHAOJIA  長崎大学, 大学院・医歯薬学総合研究科, 助教 (80457499)
Project Period (FY) 2005 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2008: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2007: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2006: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2005: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Keywords人類学 / 老化 / 骨粗鬆症 / 骨折 / 骨代謝マーカー / 死亡 / 日常生活動作
Research Abstract

横断調査で、年齢群別尿中NTX/Crについて、男性では各年齢群においてほぼ一定を示したが、女性では40歳代から50歳代にかけて高くなった。また、女性では骨量と骨折者の割合に有意差がみられ、全てのADL項目で骨折なしと答えた対象者に比べ骨折ありと答えた対象者の不自由者割合が高かった。縦断調査では1998-99年にコホート設定された女性を対象とした。死亡に対する年齢調整オッズ比を計算したところ、踵骨骨量(スティッフネス)の減少は死亡と有意な関連を示した。

Report

(5 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (27 results)

All 2008 2007 2006 2005

All Journal Article (21 results) (of which Peer Reviewed: 8 results) Presentation (6 results)

  • [Journal Article] Availability of Cardio-Ankle Vascular Index(CAVI) as a Screening Tool for Atherosclerosis2008

    • Author(s)
      Kadota K, Takamura N, Aoyagi K, et.al.
    • Journal Title

      Circulation Journal 72(2)

      Pages: 304-308

    • NAID

      110006571061

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Availability of Cardio-Ankle Vascular Index (CAVI) as a Screening Tool for Atherosclerosis.2008

    • Author(s)
      Kadota K, Aoyagi K, et al.
    • Journal Title

      Circulation Journal 72

      Pages: 304-308

    • NAID

      110006571061

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 地域在住中高年女性における新規椎体骨折とQOL2007

    • Author(s)
      青柳潔
    • Journal Title

      Osteoporosis Japan 15(3)

      Pages: 182-184

    • Related Report
      2008 Final Research Report
  • [Journal Article] Fear of Falling among Community-dwelling Elderly Women Receiving Visiting Nursing Services in Japan2007

    • Author(s)
      Takai K.
    • Journal Title

      Acta Med Nagasaki 52

      Pages: 7-11

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determinants of Self-Rated Health among Community-Dwelling Women Aged 40 Years and Over in Japan2006

    • Author(s)
      Kanagae M, Abe Y, Honda S, Takamura N, Kusano Y, Takemoto T, Aoyagi K.
    • Journal Title

      Tohoku J Exp Med 210(1)

      Pages: 11-19

    • NAID

      10019283569

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Physique, body composition and maximum oxygen consumption of selected soccer players of kunimi high school, Nagasaki, Japan2006

    • Author(s)
      Tahara Y, Aoyagi K. et.al.
    • Journal Title

      J Physiol Anthropol 25(4)

      Pages: 291-297

    • NAID

      110004751595

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prevalence and involvement patterns of radiographic hand osteoarthritis in Japanese women: the Hizen-Oshima Study2006

    • Author(s)
      Toba N, Sakai A, Aoyagi K, Yoshida S, Honda S, Nakamura T.
    • Journal Title

      J Bone Miner Metab 24(4)

      Pages: 344-348

    • NAID

      10018193715

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ethnic-, gender-, and age-related differences in femorotibial angle, femoral antetorsion, and tibiofibular torsion : cross-sectional study among healthy Japanese and Australian Caucasians2006

    • Author(s)
      Tamari K, Tinley P, Briffa K, Aoyagi K.
    • Journal Title

      Clin Anat 19(1)

      Pages: 59-67

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Obesity and Cardiovascular Risk Factors among Men and Women Aged 40 Years and Older in a Rural Area of Japan2006

    • Author(s)
      Aoyagi K., Kusano Y, Takamura N, Abe Y, Osaki M, Une H
    • Journal Title

      J Physiol Anthropol 25(6)

      Pages: 371-375

    • NAID

      110006200723

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Self-perceived Oral Health of the Elderly in a Rural Area, Japan2006

    • Author(s)
      Ugarte JL, Aoyage K et al.
    • Journal Title

      Acta Med Nagasaki 51(3)

      Pages: 89-94

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Determinants of Self-Rated Health among Community-Dwelling Women Aged 40 Years and Over in Japan2006

    • Author(s)
      Kanagae M, Aoyagi K et al.
    • Journal Title

      Tohoku J Exp Med 210(1)

      Pages: 11-19

    • NAID

      10019283569

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Prevalence and involvement patterns of radiographic hand osteoarthritis in Japanese women : the Hizen-Oshima Study2006

    • Author(s)
      Toba N, Aoyagi K, Yoshida S, Hond S, Nakamura T et al.
    • Journal Title

      J Bone Miner Metab 24(4)

      Pages: 344-348

    • NAID

      10018193715

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Early prediction of rheumatoid arthritis by serological variable and magnetic resonance imaging of the wrists and finger joints : results from prospective clinical examination2006

    • Author(s)
      Tamai M, Aoyagi K, et al.
    • Journal Title

      Ann Rheum Dis 65(1)

      Pages: 134-135

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Ethnic-, gender-, and age-related differences in femorotibial angle, femoral antetorsion, and tibiofibular torsion : cross-sectional study among healthy Japanese and Australian Caucasians2006

    • Author(s)
      Tamari K, Tinley P, Briffa K, Aoyagi K
    • Journal Title

      Clin Anat 19(1)

      Pages: 59-67

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 骨粗鬆症リスク評価ツール(FOSTA)の前腕骨骨密度による骨粗鬆症識別能2005

    • Author(s)
      富田雅人、青柳潔ら
    • Journal Title

      整形外科と災害外科 54(4)

      Pages: 631-633

    • Related Report
      2008 Final Research Report
  • [Journal Article] Relationship between falls and physical performance measures among community-dwelling elderly women in Japan2005

    • Author(s)
      Morita M, Takamura N, Kusano Y, Abe Y, Moji K, Takemoto T, Aoyagi K.
    • Journal Title

      Aging Clin Exp Res 17(3)

      Pages: 211-216

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 変形性股関節症における臼蓋骨棘形成の程度と橈骨、腰椎骨量値との関連2005

    • Author(s)
      岡野邦彦
    • Journal Title

      Hip Joint 31

      Pages: 179-181

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 関節リウマチの早期診断基準案2005

    • Author(s)
      玉井慎美
    • Journal Title

      臨床リウマチ 17

      Pages: 23-27

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Plasma concentrations of adrenomedullin and ghrelin in hemodialysis patients with sustained and episodic hypotension2005

    • Author(s)
      Iwanaga K
    • Journal Title

      Endocr J 52・1

      Pages: 23-28

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Effects of risedronate on trabecular microstructure and biomechanical properties in ovariectomized rat tibia2005

    • Author(s)
      Ito M
    • Journal Title

      Osteoporos Int 16・9

      Pages: 1042-1048

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Pilot study on the use of tourniquet : a risk factor for pulmonary thromboembolism after total knee arthroplasty?2005

    • Author(s)
      Nishiguchi M
    • Journal Title

      Thromb Res 115・4

      Pages: 271-276

    • Related Report
      2005 Annual Research Report
  • [Presentation] The association of stiffness index and cross-linked N-telopeptides of type 1 collagen with any clinical fractures differs with age and gender.2008

    • Author(s)
      Abe Y, Aoyagi K.
    • Organizer
      ASBMR 30th Annual Meeting
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2008-09-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] The association of stiffness index and cross-linked N-telopeptides of type I collagen with any clinical fractures differs with age and gender2008

    • Author(s)
      Abe Y, Aoyagi K.
    • Organizer
      ASBMR 30th Annual Me
    • Place of Presentation
      Montreal, Canada
    • Related Report
      2008 Final Research Report
  • [Presentation] Height Loss and Decreased Physical Function in Japanese Women:The Hizen-Osima study2007

    • Author(s)
      Aoyagi K.
    • Organizer
      ASBMR 29th Annual Meeting
    • Place of Presentation
      Honolulu,USA
    • Year and Date
      2007-09-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Height Loss and Decreased Physical Function in Japanese Women : The Hizen-Oshima Study2007

    • Author(s)
      Aoyagi K, Abe Y.
    • Organizer
      ASBMR 29th Annual Meeting
    • Place of Presentation
      Honolulu, USA
    • Related Report
      2008 Final Research Report
  • [Presentation] Performance of a Simple Clinical Tool (FOSTA) for Identifying Undiagnosed Osteoporosis Patients in Japanese Women : Multicenter Study2006

    • Author(s)
      Abe Y, Aoyagi K.
    • Organizer
      ASBMR 28th Annual Meeting
    • Place of Presentation
      Philadelphia, USA
    • Related Report
      2008 Final Research Report
  • [Presentation] Prediction of Vertebral Fracture Risk by Radiographic Absorptiometry and Quantitative Ultrasound in Japanese Women2005

    • Author(s)
      Abe Y, Aoyagi K.
    • Organizer
      ASBMR 27h Annual Meeting
    • Place of Presentation
      Nashville, USA
    • Related Report
      2008 Final Research Report

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Published: 2005-04-01   Modified: 2016-04-21  

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