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Effects of aerobic exercise training on brain structure in adults

Research Project

Project/Area Number 17300199
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionTohoku University

Principal Investigator

FUJIMOTO Toshihiko  Tohoku University, Center for the Advancement of Higher Education, Senior Assistant Professor (00229048)

Co-Investigator(Kenkyū-buntansha) TASHIRO Manabu  Tohoiku University・Division of Cyclotron Nuclear Medicine, Cyclotron and Radioisotope Center, Associate Professor (00333477)
伊藤 正敏  東北大学, サイクロトロン・ラジオアイソトープセンター, 教授 (00125501)
Project Period (FY) 2005 – 2007
Project Status Completed (Fiscal Year 2007)
Budget Amount *help
¥17,550,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2007: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2006: ¥4,600,000 (Direct Cost: ¥4,600,000)
Fiscal Year 2005: ¥4,500,000 (Direct Cost: ¥4,500,000)
Keywordsexercise / brain structure / MRI / middle age / 脳 / 有酸素運動 / 精神的健康度 / 海馬 / 灰白質容量 / 心理尺度
Research Abstract

Recent studies suggested that the brain structure plastically changes by learning and environmental demands even in young adults. Since high aerobic fitness capacity suppresses the brain atrophy associated with aging, it may influence the brain structure also in young adults. That may also be associated with psychological benefit of exercise. In this study, we examined the relationship between regional brain gray matter volume, estimated VO_2max and psychological well-being. Right handed university students (80 males and 21 females) who did not smoke were recruited. After the acquisition of high resolution T1 magnetic resonance (MR) images, subjects completed self-reported questionnaires measuring generalized self-efficacy, self-acceptance, subjective happiness and development of identity. Finally, VO_2max was estimated using an incremental submaximal exercise test on a cycle ergometer. Relationship between regional gray matter volume, VO_2max and psychological well-being was analyzed using optimized voxel-based morphometry technique (VBM). The results of VBM correlation analysis between regional gray matter volume and VO_2max showed positive correlation in a cluster of inferior orbital / temporal pole / insula and negative correlation in striate cortex. The gray matter volume of orbital / temporal pole / insula area was positively correlated with subjective happiness, whereas, the gray matter volume of striate cortex was negatively correlated with subjective happiness. These results suggested the possibility that aerobic fitness capacity is associated with brain structure and psychological well-being.

Report

(4 results)
  • 2007 Annual Research Report   Final Research Report Summary
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (20 results)

All 2007 2005

All Journal Article (9 results) (of which Peer Reviewed: 4 results) Presentation (11 results)

  • [Journal Article] 課題達成型のダンス運動が健常者および統合失調症患者の気分に及ぼす効果2007

    • Author(s)
      泉水 宏臣, ら
    • Journal Title

      体力研究 105

      Pages: 11-16

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] Effects of goal oriented dance exerise on mood in healthy young adults and schizophrenic patients2007

    • Author(s)
      Sensui H et. al.
    • Journal Title

      Bulletin of Physical Fitness Research Institute 105

      Pages: 11-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] 課題達成型のダンス運動が健常者および統合失調症患者の気分に及ぼす効果2007

    • Author(s)
      泉水 宏臣, 今村弥生, 藤本敏彦, ら
    • Journal Title

      体力研究 105

      Pages: 11-16

    • NAID

      130005865193

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High intensity exercise decreases global brain glucose uptake in humans.2005

    • Author(s)
      Kemppainen J. , et. al.
    • Journal Title

      J Physiol. 568(Pt.1)

      Pages: 323-332

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] In vivo measurements of glucose uptake in human Achilles tendon during different exercise intensities.2005

    • Author(s)
      Hannukainen J. , et. al.
    • Journal Title

      Int J Sports Med. 26(9)

      Pages: 727-731

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
    • Peer Reviewed
  • [Journal Article] High intensity exercise decreases global brain glucose uptake in humans2005

    • Author(s)
      Kemppainen J. et. al.
    • Journal Title

      J Physiol 568(Pt 1)

      Pages: 323-332

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] Invivo measurements of glucose uptake in human Achilles tendon during different exercise intensities2005

    • Author(s)
      Hannukainen J. et. al.
    • Journal Title

      Int J Sports Med. 26(9)

      Pages: 727-731

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Journal Article] High intensity exercise decreases global brain glucose uptake in humans.2005

    • Author(s)
      Kemppainen J, Aalto S, Fujimoto T. et al.
    • Journal Title

      J Physiol. 568(Pt.1)

      Pages: 323-332

    • Related Report
      2005 Annual Research Report
  • [Journal Article] In vivo measurements of glucose uptake in human Achilles tendon during different exercise intensities.2005

    • Author(s)
      Hannukainen J, Kalliokoski KK, Nuutila P, Fujimoto T. et al.
    • Journal Title

      Int J Sports Med. 26(9)

      Pages: 727-731

    • Related Report
      2005 Annual Research Report
  • [Presentation] 中等度強度のダンス運動トレーニングが感情刺激時の脳活動に及ぼす影響.2007

    • Author(s)
      泉水弘臣, ら
    • Organizer
      第62回日本体力医学会大会
    • Place of Presentation
      ノースアジア大学・秋田市
    • Year and Date
      2007-09-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] 中等度強度のダンス運動トレーニングが精神的健康度に及ぼす影響.2007

    • Author(s)
      永松俊哉, ら
    • Organizer
      第62回日本体力医学会大会
    • Place of Presentation
      ノースアジア大学・秋田市
    • Year and Date
      2007-09-16
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effect of dance exercise at middle intensity on brain activity during mood stimulation2007

    • Author(s)
      Sensui H. ed. al.
    • Organizer
      62th Japanese Society of Physical Fitness and Sports Medicine
    • Place of Presentation
      North Asia University, Akita, Japan
    • Year and Date
      2007-09-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] Effect of dance exercise at middle intensity on mood2007

    • Author(s)
      Nagamatsu T. ed. al.
    • Organizer
      62th Japanese Society of Physical Fitness and Sports Medicine
    • Place of Presentation
      North Asia University, Akita, Japan
    • Year and Date
      2007-09-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 中等度強度のダンス運動トレーニングが精神的健康度に及ぼす影響2007

    • Author(s)
      永松俊哉, 泉水弘臣, 菊地吉晃, ら
    • Organizer
      第62回日本体力医学会大会
    • Place of Presentation
      ノースアジア大学・秋田市
    • Year and Date
      2007-09-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] 有酸素トレーニングによる脳構造と精神的健康度への影響.2007

    • Author(s)
      権藤雄一, ら
    • Organizer
      第62回日本体力医学会大会
    • Place of Presentation
      ノースアジア大学・秋田市
    • Year and Date
      2007-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Effects of aerobic exercise training on brain structure and psychological well-being in young adults2007

    • Author(s)
      Gondoh Y. ed. al.
    • Organizer
      62th Japanese Society of Physical Fitness and Sports Medicine
    • Place of Presentation
      North Asia University, Akita, Japan
    • Year and Date
      2007-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] 一過性の中等度運動が精神疾患患者の気分に及ぼす効果.2007

    • Author(s)
      泉水宏臣, ら
    • Organizer
      日本体育学会第58回大会.
    • Place of Presentation
      神戸大学・神戸市
    • Year and Date
      2007-09-05
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] Effects of temporal exerxise on mood in schizophrenic patients2007

    • Author(s)
      Sensui H. ed. al.
    • Organizer
      58th Conference of Japan Society of Physical Education, Health and Sport Sciences
    • Place of Presentation
      Kobe University, Kobe, Hyogo, Japan
    • Year and Date
      2007-09-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary
  • [Presentation] The effect of exercise training on gray matter structure of adults human brain.2007

    • Author(s)
      Sensui H. , et. al.
    • Organizer
      12th Annual Congress of the European College of Sport Science.
    • Place of Presentation
      Paviljonki・Jyvaskyla・Finland
    • Year and Date
      2007-07-14
    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2007 Annual Research Report 2007 Final Research Report Summary
  • [Presentation] The effect of exercise training on gray matter structure of adults human brain2007

    • Author(s)
      Sensui H. ed. al.
    • Organizer
      12th Annual Congress of the European College of Sport Science
    • Place of Presentation
      Paviljonki・Jyvaskyla・Finland
    • Year and Date
      2007-07-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2007 Final Research Report Summary

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Published: 2005-04-01   Modified: 2016-04-21  

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